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Academic Journal

WNT5B promotes the malignant phenotype of non-small cell lung cancer via the FZD3-DVL3-RAC1-PCP-JNK pathway.

  • Authors : Zhao H; Department of Pathology, The First Hospital and College of Basic Medical Sciences, China Medical University, Shenyang, China. Electronic address: .; Wu G

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/metabolism ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/pathology ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics

  • Source: Cellular signalling [Cell Signal] 2024 Oct; Vol. 122, pp. 111330. Date of Electronic Publication: 2024 Jul 31.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8904683 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

RAC1 inhibition ameliorates IBSP-induced bone metastasis in lung adenocarcinoma.

  • Authors : Zhang X; School of Medicine, Tongji University, Shanghai 200433, China; Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China.

Subjects: rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/rac1 GTP-Binding Protein*/metabolism ; Bone Neoplasms*/Bone Neoplasms*/Bone Neoplasms*/secondary ; Bone Neoplasms*/Bone Neoplasms*/Bone Neoplasms*/metabolism

  • Source: Cell reports [Cell Rep] 2024 Aug 27; Vol. 43 (8), pp. 114528. Date of Electronic Publication: 2024 Jul 24.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma.

  • Authors : Cooke M; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Medicine, Einstein Medical Center Philadelphia, Philadelphia, PA 19141, USA.

Subjects: Adenocarcinoma of Lung/Adenocarcinoma of Lung/Adenocarcinoma of Lung/*enzymology ; Guanine Nucleotide Exchange Factors/Guanine Nucleotide Exchange Factors/Guanine Nucleotide Exchange Factors/*metabolism ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*enzymology

  • Source: Cell reports [Cell Rep] 2021 Nov 02; Vol. 37 (5), pp. 109905.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247

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Academic Journal

Tumour-derived exosomal lncRNA-SOX2OT promotes bone metastasis of non-small cell lung cancer by targeting the miRNA-194-5p/RAC1 signalling axis in osteoclasts.

  • Authors : Ni J; Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.

Subjects: Cell Movement*; Bone Neoplasms/Bone Neoplasms/Bone Neoplasms/*metabolism ; Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*metabolism

  • Source: Cell death & disease [Cell Death Dis] 2021 Jul 02; Vol. 12 (7), pp. 662. Date of Electronic Publication: 2021 Jul 02.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Development of an Improved Guanidine-Based Rac1 Inhibitor with in vivo Activity against Non-Small Cell Lung Cancer.

  • Authors : Ciarlantini MS; Departamento de Ingredientes Activos y Biorrefinerías, Instituto Nacional de Tecnología Industrial, Av. General Paz 5445, B1650WAB, San Martin Buenos Aires, Argentina.; Barquero A

Subjects: Drug Development*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*drug therapy

  • Source: ChemMedChem [ChemMedChem] 2021 Mar 18; Vol. 16 (6), pp. 1011-1021. Date of Electronic Publication: 2021 Jan 25.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187

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Academic Journal

Different signaling and functionality of Rac1 and Rac1b in the progression of lung adenocarcinoma.

  • Authors : Seiz JR; Molecular Oncology of Solid Tumors, Internal Medicine, Science Unit for Basic and Clinical Medicine, Justus Liebig University Giessen, Aulweg 128, D-35392 Giessen, Germany.; Klinke J

Subjects: Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*metabolism ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*metabolism ; rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/rac1 GTP-Binding Protein/*metabolism

  • Source: Biological chemistry [Biol Chem] 2020 Mar 26; Vol. 401 (4), pp. 517-531.Publisher: Walter De Gruyter Country of Publication: Germany NLM ID: 9700112 Publication Model: Print Cited Medium: Internet ISSN: 1437-4315

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Academic Journal

High Expression of UBB , RAC1 , and ITGB1 Predicts Worse Prognosis among Nonsmoking Patients with Lung Adenocarcinoma through Bioinformatics Analysis.

  • Authors : Deng H; Department of Radiation Oncology, Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou 310022, China.; Institute of Cancer Research and Basic Medical (IBMC), Chinese Academy of Sciences, Hangzhou 310022, China.

Subjects: Adenocarcinoma of Lung/Adenocarcinoma of Lung/Adenocarcinoma of Lung/*genetics ; Carcinogenesis/Carcinogenesis/Carcinogenesis/*genetics ; Integrin beta1/Integrin beta1/Integrin beta1/*genetics

  • Source: BioMed research international [Biomed Res Int] 2020 Oct 20; Vol. 2020, pp. 2071593. Date of Electronic Publication: 2020 Oct 20 (Print Publication: 2020).Publisher: Hindawi Pub. Co Country of Publication: United States NLM ID: 101600173 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Smoking-associated upregulation of CBX3 suppresses ARHGAP24 expression to activate Rac1 signaling and promote tumor progression in lung adenocarcinoma.

  • Authors : Jin X; Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.; Uro-Oncology Institute of Central South University, Changsha, Hunan, 410011, China.

Subjects: Adenocarcinoma of Lung/Adenocarcinoma of Lung/Adenocarcinoma of Lung/*etiology ; Chromosomal Proteins, Non-Histone/Chromosomal Proteins, Non-Histone/Chromosomal Proteins, Non-Histone/*metabolism ; GTPase-Activating Proteins/GTPase-Activating Proteins/GTPase-Activating Proteins/*metabolism

  • Source: Oncogene [Oncogene] 2022 Jan; Vol. 41 (4), pp. 538-549. Date of Electronic Publication: 2021 Nov 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Long noncoding RNA LCAT1 functions as a ceRNA to regulate RAC1 function by sponging miR-4715-5p in lung cancer.

  • Authors : Yang J; Department of Respiratory Medicine, Sir Run Run Shaw Hospital and Institute of Translational Medicine, Zhejiang University School of Medicine, Zhejiang, 310016, Hangzhou, China.; Qiu Q

Subjects: Gene Expression Regulation, Neoplastic* ; RNA Interference* ; RNA, Long Noncoding*

  • Source: Molecular cancer [Mol Cancer] 2019 Nov 29; Vol. 18 (1), pp. 171. Date of Electronic Publication: 2019 Nov 29.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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Academic Journal

Rac1-mediated sustained β4 integrin level develops reattachment ability of breast cancer cells after anchorage loss.

  • Authors : Mori K; Division of Cancer Cell Biology, Department of Pharmaceutical Sciences, Showa University School of Pharmacy, Tokyo, Japan.; Higurashi M

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Integrin beta4/Integrin beta4/Integrin beta4/*metabolism ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*metabolism

  • Source: Cancer science [Cancer Sci] 2021 Aug; Vol. 112 (8), pp. 3205-3217. Date of Electronic Publication: 2021 Jun 16.Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic

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  • 1-10 of  92 results for ""rac1 GTP-Binding Protein""