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Academic Journal

Cancer-associated fibroblasts promote the progression and chemoresistance of HCC by inducing IGF-1.

  • Authors : Lv KJ; Phase I clinical trial research ward, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, PR China.; Yu SZ

Subjects: Cancer-Associated Fibroblasts*/Cancer-Associated Fibroblasts*/Cancer-Associated Fibroblasts*/metabolism ; Cancer-Associated Fibroblasts*/Cancer-Associated Fibroblasts*/Cancer-Associated Fibroblasts*/pathology ; Insulin-Like Growth Factor I*/Insulin-Like Growth Factor I*/Insulin-Like Growth Factor I*/metabolism

  • Source: Cellular signalling [Cell Signal] 2024 Dec; Vol. 124, pp. 111378. Date of Electronic Publication: 2024 Sep 04.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8904683 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Preclinical and phase I studies of an antisense oligonucleotide drug targeting IGF-1R in liver cancer.

  • Authors : Li Y; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China.; Xu Z

Subjects: Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/drug therapy ; Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/genetics ; Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/pathology

  • Source: Future oncology (London, England) [Future Oncol] 2024; Vol. 20 (34), pp. 2671-2684. Date of Electronic Publication: 2024 Apr 04.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101256629 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Immunohistochemical Expression of Insulin-Like Growth Factor-1 Receptor and Its Association with Clinicopathological Parameters in Hepatocellular Carcinoma.

  • Authors : Peloso Maia ML; Department of Anatomic Pathology, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.; Albuquerque RM

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/pathology ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/metabolism ; Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/pathology

  • Source: Oncology [Oncology] 2024; Vol. 102 (6), pp. 494-502. Date of Electronic Publication: 2023 Nov 21.Publisher: Karger Country of Publication: Switzerland NLM ID: 0135054 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1423-0232

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Academic Journal

IGF-1R down regulates the sensitivity of hepatocellular carcinoma to sorafenib through the PI3K / akt and RAS / raf / ERK signaling pathways.

  • Authors : Cai W; Medical school, Anhui University of Science and Technology, 232001, Huainan, China.; Medical School, Anhui University of Science & Technology, Class 8, Grade 18, Clinical Major, 232001, Huainan, China.

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/drug therapy ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/genetics ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/metabolism

  • Source: BMC cancer [BMC Cancer] 2023 Jan 25; Vol. 23 (1), pp. 87. Date of Electronic Publication: 2023 Jan 25.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

The regulation of proliferation and apoptosis in hepatocellular carcinoma via insulin-like growth factor 1 receptor.

  • Authors : Xu G; Department of Oncology, The Third People's Hospital of Jiujiang, Jiujiang 332000, China. Electronic address: .; Chu J

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/genetics ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/metabolism ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/pathology

  • Source: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Publisher: Elsevier Country of Publication: Scotland NLM ID: 9814320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2238

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Academic Journal

Circular RNA circ_0001459 accelerates hepatocellular carcinoma progression via the miR-6165/IGF1R axis.

  • Authors : Shen D; Medical School, Southeast University, Nanjing, China.; Zhao H

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/genetics ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/pathology ; Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/genetics

  • Source: Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2022 Jun; Vol. 1512 (1), pp. 46-60. Date of Electronic Publication: 2022 Feb 23.Publisher: New York Academy of Sciences Country of Publication: United States NLM ID: 7506858 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Differential expression of insulin-like growth factor type 1 receptor identifies heterogeneous intrahepatic regulatory T subsets in mouse hepatocellular carcinoma.

  • Authors : Huang Y; Department of Pathology, Renmin Hospital of Wuhan University, Wuhan 430060, PR China.; Huang L

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/metabolism ; Liver Neoplasms*/Liver Neoplasms*/Liver Neoplasms*/metabolism ; Receptor, IGF Type 1*/Receptor, IGF Type 1*/Receptor, IGF Type 1*/genetics

  • Source: Clinical and experimental immunology [Clin Exp Immunol] 2022 May 13; Vol. 208 (1), pp. 47-59.Publisher: Oxford University Press Country of Publication: England NLM ID: 0057202 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Overexpression of BACH1 mediated by IGF2 facilitates hepatocellular carcinoma growth and metastasis via IGF1R and PTK2.

  • Authors : Xie M; Department of Gastroenterology, Institute of Liver and Gastrointestinal Diseases, Hubei Key Laboratory of Hepato-Pancreato-Biliary Diseases, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China.; Hubei Key Laboratory of Hepato-Pancreato-Biliary Diseases

Subjects: Basic-Leucine Zipper Transcription Factors*/Basic-Leucine Zipper Transcription Factors*/Basic-Leucine Zipper Transcription Factors*/biosynthesis ; Basic-Leucine Zipper Transcription Factors*/Basic-Leucine Zipper Transcription Factors*/Basic-Leucine Zipper Transcription Factors*/genetics ; Basic-Leucine Zipper Transcription Factors*/Basic-Leucine Zipper Transcription Factors*/Basic-Leucine Zipper Transcription Factors*/metabolism

  • Source: Theranostics [Theranostics] 2022 Jan 01; Vol. 12 (3), pp. 1097-1116. Date of Electronic Publication: 2022 Jan 01 (Print Publication: 2022).Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101552395 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Insulin-Like Growth Factor 1 Receptor Drives Hepatocellular Carcinoma Growth and Invasion by Activating Stat3-Midkine-Stat3 Loop.

  • Authors : Bie C; Department of Gastroenterology, The Affiliated Shenzhen Shajing Hospital, Guangzhou Medical University, Shenzhen, 518104, Guangdong, People's Republic of China.; Chen Y

Subjects: Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*genetics ; Janus Kinase 1/Janus Kinase 1/Janus Kinase 1/*genetics ; Liver Neoplasms/Liver Neoplasms/Liver Neoplasms/*genetics

  • Source: Digestive diseases and sciences [Dig Dis Sci] 2022 Feb; Vol. 67 (2), pp. 569-584. Date of Electronic Publication: 2021 Feb 09.Publisher: Springer Science + Business Media Country of Publication: United States NLM ID: 7902782 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

The Role of IGF/IGF-1R Signaling in Hepatocellular Carcinomas: Stemness-Related Properties and Drug Resistance.

  • Authors : Ngo MT; International PhD Program for Cell Therapy and Regeneration Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.; Department of Biochemistry and Molecular Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.

Subjects: Signal Transduction*; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*metabolism ; Liver Neoplasms/Liver Neoplasms/Liver Neoplasms/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Feb 16; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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  • 1-10 of  128 results for ""Receptor, IGF Type 1""