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Academic Journal

Secreted acid sphingomyelinase as a potential gene therapy for limb girdle muscular dystrophy 2B.

  • Authors : Bittel DC; Center for Genetic Medicine Research, Children's National Hospital, Washington, DC, USA.; Sreetama SC

Subjects: Dependovirus* ; Genetic Therapy* ; Genetic Vectors*

  • Source: The Journal of clinical investigation [J Clin Invest] 2022 Jan 04; Vol. 132 (1).Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium:

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Academic Journal

Acid and Neutral Sphingomyelinase Behavior in Radiation-Induced Liver Pyroptosis and in the Protective/Preventive Role of rMnSOD.

  • Authors : Cataldi S; Department of Pharmaceutical Sciences, University of Perugia, 06126 Perugia, Italy.; Borrelli A

Subjects: Pyroptosis*; Liver/Liver/Liver/*metabolism ; Radiation Injuries/Radiation Injuries/Radiation Injuries/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2020 May 06; Vol. 21 (9). Date of Electronic Publication: 2020 May 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Acid Sphingomyelinase Inhibition Prevents Development of Sepsis Sequelae in the Murine Liver.

  • Authors : Chung HY; Center for Sepsis Control and Care, Jena University Hospital, Jena, 07747, Germany.; Department of Anesthesiology and Intensive Care, Jena University Hospital, Am Klinikum 1, Jena, 07747, Germany.

Subjects: Desipramine/Desipramine/Desipramine/*pharmacology ; Liver/Liver/Liver/*drug effects ; Liver Cirrhosis/Liver Cirrhosis/Liver Cirrhosis/*prevention & control

  • Source: Scientific reports [Sci Rep] 2017 Sep 27; Vol. 7 (1), pp. 12348. Date of Electronic Publication: 2017 Sep 27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Inhibition of neutral sphingomyelinase decreases elevated levels of nitrative and oxidative stress markers in liver ischemia-reperfusion injury.

  • Authors : Unal B; a Department of Pathology, Faculty of Medicine , Akdeniz University , Antalya 07070 , Turkey.; Ozcan F

Subjects: Liver/Liver/Liver/*enzymology ; Liver/Liver/Liver/*pathology ; Reperfusion Injury/Reperfusion Injury/Reperfusion Injury/*enzymology

  • Source: Redox report : communications in free radical research [Redox Rep] 2017 Jul; Vol. 22 (4), pp. 147-159. Date of Electronic Publication: 2016 Mar 24.Publisher: Taylor & Francis Country of Publication: England NLM ID: 9511366 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Neutral sphingomyelinase inhibition alleviates apoptosis, but not ER stress, in liver ischemia-reperfusion injury.

  • Authors : Tuzcu H; a Department of Medical Biochemistry , Akdeniz University Faculty of Medicine , Antalya , Turkey.; Unal B

Subjects: Apoptosis/Apoptosis/Apoptosis/*drug effects ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*administration & dosage ; Liver/Liver/Liver/*drug effects

  • Source: Free radical research [Free Radic Res] 2017 Mar; Vol. 51 (3), pp. 253-268. Date of Electronic Publication: 2017 Mar 13.Publisher: Informa Healthcare Country of Publication: England NLM ID: 9423872 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Acid Sphingomyelinase Inhibition Stabilizes Hepatic Ceramide Content and Improves Hepatic Biotransformation Capacity in a Murine Model of Polymicrobial Sepsis.

  • Authors : Chung HY; Center for Sepsis Control and Care, Jena University Hospital, 07747 Jena, Germany. .; Hans-Berger Department of Neurology, Jena University Hospital, 07747 Jena, Germany. .

Subjects: Biotransformation/Biotransformation/Biotransformation/*drug effects ; Ceramides/Ceramides/Ceramides/*metabolism ; Liver/Liver/Liver/*drug effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2018 Oct 15; Vol. 19 (10). Date of Electronic Publication: 2018 Oct 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Peripheral Acid Sphingomyelinase Activity Is Associated with Biomarkers and Phenotypes of Alcohol Use and Dependence in Patients and Healthy Controls.

  • Authors : Mühle C; Department of Psychiatry and Psychotherapy, Friedrich-Alexander University Erlangen-Nürnberg (FAU), D-91054 Erlangen, Germany. .; Weinland C

Subjects: Alcoholism/Alcoholism/Alcoholism/*diagnosis ; Biomarkers/Biomarkers/Biomarkers/*blood ; Liver/Liver/Liver/*enzymology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2018 Dec 13; Vol. 19 (12). Date of Electronic Publication: 2018 Dec 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Serum acid sphingomyelinase is upregulated in chronic hepatitis C infection and non alcoholic fatty liver disease.

  • Authors : Grammatikos G; Pharmazentrum Frankfurt, Institut für Allgemeine Pharmakologie und Toxikologie, Frankfurt am Main, Germany; Goethe University Hospital, Medizinische Klinik 1, Frankfurt am Main, Germany. Electronic address: .

Subjects: Fatty Liver/Fatty Liver/Fatty Liver/*blood ; Hepatitis C, Chronic/Hepatitis C, Chronic/Hepatitis C, Chronic/*blood ; Liver/Liver/Liver/*metabolism

  • Source: Biochimica et biophysica acta [Biochim Biophys Acta] 2014 Jul; Vol. 1841 (7), pp. 1012-20. Date of Electronic Publication: 2014 Apr 25.Publisher: Elsevier Pub. Co Country of Publication: Netherlands NLM ID: 0217513 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Liver acid sphingomyelinase inhibits growth of metastatic colon cancer.

  • Authors : Osawa Y; Department of Pharmacology, Gifu University Graduate School of Medicine, 1-1 Yanagido Gifu 501-1194, Japan. ; Suetsugu A

Subjects: Colonic Neoplasms*; Liver/Liver/Liver/*enzymology ; Liver Neoplasms, Experimental/Liver Neoplasms, Experimental/Liver Neoplasms, Experimental/*enzymology

  • Source: The Journal of clinical investigation [J Clin Invest] 2013 Feb; Vol. 123 (2), pp. 834-43. Date of Electronic Publication: 2013 Jan 09.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited

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Academic Journal

Liver and skin histopathology in adults with acid sphingomyelinase deficiency (Niemann-Pick disease type B).

Subjects: Liver/Liver/Liver/*pathology ; Niemann-Pick Disease, Type B/Niemann-Pick Disease, Type B/Niemann-Pick Disease, Type B/*drug therapy ; Niemann-Pick Disease, Type B/Niemann-Pick Disease, Type B/Niemann-Pick Disease, Type B/*pathology

  • Source: The American journal of surgical pathology [Am J Surg Pathol] 2012 Aug; Vol. 36 (8), pp. 1234-46.Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 7707904 Publication Model: Print Cited Medium: Internet ISSN:

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  • 1-10 of  104 results for ""Sphingomyelin Phosphodiesterase""