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Academic Journal

PNPLA3 is a triglyceride lipase that mobilizes polyunsaturated fatty acids to facilitate hepatic secretion of large-sized very low-density lipoprotein.

  • Authors : Johnson SM; Department of Biochemistry and Molecular Biology; Mayo Clinic College of Medicine & Science, Rochester, MN, 55905, USA.

Subjects: Lipase*/Lipase*/Lipase*/metabolism ; Lipase*/Lipase*/Lipase*/genetics ; Liver*/Liver*/Liver*/metabolism

  • Source: Nature communications [Nat Commun] 2024 Jun 06; Vol. 15 (1), pp. 4847. Date of Electronic Publication: 2024 Jun 06.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Statin-associated regulation of hepatic PNPLA3 in patients without known liver disease.

  • Authors : Ahmed O; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.; Cardiovascular Research Theme, Bioclinicum J8, Karolinska University Hospital, Solna, Sweden.

Subjects: Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use ; Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/pharmacology ; Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/genetics

  • Source: Journal of internal medicine [J Intern Med] 2025 Jan; Vol. 297 (1), pp. 47-59. Date of Electronic Publication: 2024 Nov 19.Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 8904841 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Associations of dietary sugars with liver stiffness in Latino adolescents with obesity differ on PNPLA3 and liver disease severity.

  • Authors : Schenker RB; Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Children's Hospital Los Angeles, Los Angeles, California, USA.; Machle CJ

Subjects: Dietary Sugars*/Dietary Sugars*/Dietary Sugars*/adverse effects ; Lipase*/Lipase*/Lipase*/genetics ; Liver*/Liver*/Liver*/pathology

  • Source: Liver international : official journal of the International Association for the Study of the Liver [Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101160857 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Lipase family member N is a novel target gene for CCAAT/enhancer-binding protein α in type 2 diabetic model mouse liver.

  • Authors : Aibara D; Faculty of Pharmaceutical Science, Fukuoka University, Fukuoka 814-0180, Japan.; Matsuo K

Subjects: Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/genetics ; Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/Diabetes Mellitus, Type 2*/metabolism; CCAAT-Enhancer-Binding Protein-alpha/CCAAT-Enhancer-Binding Protein-alpha/CCAAT-Enhancer-Binding Protein-alpha/*metabolism

  • Source: Endocrine journal [Endocr J] 2022 May 30; Vol. 69 (5), pp. 567-575. Date of Electronic Publication: 2022 Jan 27.Publisher: Japan Endocrine Society Country of Publication: Japan NLM ID: 9313485 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Hepatocyte-specific deletion of adipose triglyceride lipase (adipose triglyceride lipase/patatin-like phospholipase domain containing 2) ameliorates dietary induced steatohepatitis in mice.

  • Authors : Fuchs CD; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.; Radun R

Subjects: Lipase/Lipase/Lipase/*metabolism ; Lipolysis/Lipolysis/Lipolysis/*immunology ; Liver/Liver/Liver/*pathology

  • Source: Hepatology (Baltimore, Md.) [Hepatology] 2022 Jan; Vol. 75 (1), pp. 125-139. Date of Electronic Publication: 2021 Dec 04.Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Integrated Action of Autophagy and Adipose Tissue Triglyceride Lipase Ameliorates Diet-Induced Hepatic Steatosis in Liver-Specific PLIN2 Knockout Mice.

  • Authors : Griffin JD; Obesity and Metabolism Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA.; Bejarano E

Subjects: Autophagy*; Adipose Tissue/Adipose Tissue/Adipose Tissue/*enzymology ; Diet/Diet/Diet/*adverse effects

  • Source: Cells [Cells] 2021 Apr 25; Vol. 10 (5). Date of Electronic Publication: 2021 Apr 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Signatures of positive selection on the hepatic lipase gene in human populations.

  • Authors : Flores SV; Laboratorio de Genética y Bioantropología, Departamento de Antropología, Facultad de Ciencias Sociales, Universidad de Chile, Avenida Ignacio Carrera Pinto 1045, Ñuñoa 7750000, Santiago, Chile. .; Olivari CF

Subjects: Lipase/Lipase/Lipase/*genetics ; Liver/Liver/Liver/*enzymology; Gene Frequency

  • Source: Journal of genetics [J Genet] 2020 Mar; Vol. 99.Publisher: Springer India in co-pulbication with Indian Academy of Sciences Country of Publication: India NLM ID: 2985113R Publication Model: Print Cited

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Academic Journal

Bile acids induced hepatic lipid accumulation in mice by inhibiting mRNA expression of patatin-like phospholipase domain containing 3 and microsomal triglyceride transfer protein.

  • Authors : Hashimoto N; Department of Life and Food Sciences, Obihiro University of Agriculture and Veterinary Medicine, Nishi 2-11, Inada, Obihiro, Hokkaido 080-8555, Japan; Division of Food Function Research, Food Research Institute, National Agriculture and Food Research Organization, 2-1-12, Kannondai, Tsukuba, Ibaraki 305-8642, Japan

Subjects: Bile Acids and Salts/Bile Acids and Salts/Bile Acids and Salts/*adverse effects ; Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism ; Lipase/Lipase/Lipase/*metabolism

  • Source: Nutrition research (New York, N.Y.) [Nutr Res] 2021 Aug; Vol. 92, pp. 12-20. Date of Electronic Publication: 2021 May 26.Publisher: Elsevier Science Country of Publication: United States NLM ID: 8303331 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

An automated method for measuring lipoprotein lipase and hepatic triglyceride lipase activities in post-heparin plasma.

  • Authors : Nakajima K; Department of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan.; Machida T

Subjects: Automation*; Lipase/Lipase/Lipase/*blood ; Lipoproteins/Lipoproteins/Lipoproteins/*metabolism

  • Source: Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2018 Dec; Vol. 487, pp. 54-59. Date of Electronic Publication: 2018 Sep 12.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 1302422 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The role of plasma lipoprotein lipase, hepatic lipase and GPIHBP1 in the metabolism of remnant lipoproteins and small dense LDL in patients with coronary artery disease.

  • Authors : Muraba Y; Department of Clinical Laboratory Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan; Hidaka Hospital, Takasaki, Gunma, Japan. Electronic address: .

Subjects: Cholesterol, LDL/Cholesterol, LDL/Cholesterol, LDL/*metabolism ; Coronary Artery Disease/Coronary Artery Disease/Coronary Artery Disease/*metabolism ; Lipase/Lipase/Lipase/*metabolism

  • Source: Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2018 Jan; Vol. 476, pp. 146-153. Date of Electronic Publication: 2017 Nov 22.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 1302422 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  5,808 results for ""Lipase""