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Academic Journal

Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis.

  • Authors : Matz-Soja M; Institute of Biochemistry, Faculty of Medicine, Leipzig University, Leipzig, Germany.; Rennert C

Subjects: Lipid Metabolism* ; Signal Transduction*; Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/*metabolism

  • Source: ELife [Elife] 2016 May 17; Vol. 5. Date of Electronic Publication: 2016 May 17.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Cell Cycle-Related Kinase (CCRK) regulates ciliogenesis and Hedgehog signaling in mice.

  • Authors : Snouffer A; Department of Genetics, University of Georgia, Athens, GA, United States of America.; Brown D

Subjects: Cilia/Cilia/Cilia/*genetics ; Cyclin-Dependent Kinases/Cyclin-Dependent Kinases/Cyclin-Dependent Kinases/*genetics ; Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/*genetics

  • Source: PLoS genetics [PLoS Genet] 2017 Aug 17; Vol. 13 (8), pp. e1006912. Date of Electronic Publication: 2017 Aug 17 (Print Publication: 2017).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

GLI3 repressor determines Hedgehog pathway activation and is required for response to SMO antagonist glasdegib in AML.

  • Authors : Chaudhry P; Division of Hematology, Department of Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA; and.

Subjects: Hedgehog Proteins/Hedgehog Proteins/Hedgehog Proteins/*metabolism ; Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/*physiology ; Leukemia, Myeloid, Acute/Leukemia, Myeloid, Acute/Leukemia, Myeloid, Acute/*metabolism

  • Source: Blood [Blood] 2017 Jun 29; Vol. 129 (26), pp. 3465-3475. Date of Electronic Publication: 2017 May 09.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Kruppel-Like Factor 4 represses osteoblast differentiation via ciliary Hedgehog signaling.

  • Authors : Takeuchi Y; Department of Oral Anatomy and Developmental Biology, Osaka University Graduate School of Dentistry, Osaka, Japan; Department of Orthodontics and Dentofacial Orthopedics, Osaka University Graduate School of Dentistry, Osaka, Japan.

Subjects: Calcification, Physiologic/Calcification, Physiologic/Calcification, Physiologic/*genetics ; Cilia/Cilia/Cilia/*metabolism ; Hedgehog Proteins/Hedgehog Proteins/Hedgehog Proteins/*genetics

  • Source: Experimental cell research [Exp Cell Res] 2018 Oct 15; Vol. 371 (2), pp. 417-425. Date of Electronic Publication: 2018 Sep 05.Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc.

  • Authors : Liang R; Department of Internal Medicine III and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany.; Šumová B

Subjects: Hedgehog Proteins/Hedgehog Proteins/Hedgehog Proteins/*metabolism ; Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/*metabolism ; Pulmonary Fibrosis/Pulmonary Fibrosis/Pulmonary Fibrosis/*metabolism

  • Source: Annals of the rheumatic diseases [Ann Rheum Dis] 2017 Apr; Vol. 76 (4), pp. 756-764. Date of Electronic Publication: 2016 Oct 28.Publisher: BMJ Country of Publication: England NLM ID: 0372355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2060

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Academic Journal

Up-regulation of 11β-Hydroxysteroid Dehydrogenase Type 2 Expression by Hedgehog Ligand Contributes to the Conversion of Cortisol Into Cortisone.

  • Authors : Zhu H; Department of Obstetrics and Gynaecology (H.Z.), The First Affiliated Hospital, and Department of Endocrinology (C.Z., W.X., L.T.), The Children's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, People's Republic of China; and Department of Pharmacology (X.F., X.W., C.T.), School of Medicine, Zhejiang University, Hangzhou 310058, People's Republic of China.

Subjects: 11-beta-Hydroxysteroid Dehydrogenase Type 2/11-beta-Hydroxysteroid Dehydrogenase Type 2/11-beta-Hydroxysteroid Dehydrogenase Type 2/*metabolism ; Hedgehog Proteins/Hedgehog Proteins/Hedgehog Proteins/*metabolism ; Hydrocortisone/Hydrocortisone/Hydrocortisone/*metabolism

  • Source: Endocrinology [Endocrinology] 2016 Sep; Vol. 157 (9), pp. 3529-39. Date of Electronic Publication: 2016 Jul 05.Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375040 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression.

  • Authors : Hyun J; Department of Integrated Biological Science, College of Natural Science, Pusan National University, Pusan 46241, Korea.; Wang S

Subjects: Hepatic Stellate Cells/Hepatic Stellate Cells/Hepatic Stellate Cells/*metabolism ; Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/*metabolism ; Liver Cirrhosis/Liver Cirrhosis/Liver Cirrhosis/*genetics

  • Source: Nature communications [Nat Commun] 2016 Mar 22; Vol. 7, pp. 10993. Date of Electronic Publication: 2016 Mar 22.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Non-canonical GLI1/2 activation by PI3K/AKT signaling in renal cell carcinoma: A novel potential therapeutic target.

  • Authors : Zhou J; Department of Urology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.; Zhu G

Subjects: Carcinoma, Renal Cell/Carcinoma, Renal Cell/Carcinoma, Renal Cell/*etiology ; Kidney Neoplasms/Kidney Neoplasms/Kidney Neoplasms/*etiology ; Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/*physiology

  • Source: Cancer letters [Cancer Lett] 2016 Jan 28; Vol. 370 (2), pp. 313-23. Date of Electronic Publication: 2015 Nov 11.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The Orphan G Protein-coupled Receptor Gpr175 (Tpra40) Enhances Hedgehog Signaling by Modulating cAMP Levels.

  • Authors : Singh J; From the Department of Molecular Biology, Genentech, South San Francisco, California 94080.; Wen X

Subjects: Cyclic AMP/Cyclic AMP/Cyclic AMP/*metabolism ; Hedgehog Proteins/Hedgehog Proteins/Hedgehog Proteins/*metabolism ; Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/Kruppel-Like Transcription Factors/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2015 Dec 04; Vol. 290 (49), pp. 29663-75. Date of Electronic Publication: 2015 Oct 08.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

FOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast Cancer.

  • Authors : Han B; Department of Surgery, Samuel Oschin Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Qu Y

Subjects: Gene Expression Regulation, Neoplastic*; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Forkhead Transcription Factors/Forkhead Transcription Factors/Forkhead Transcription Factors/*metabolism

  • Source: Cell reports [Cell Rep] 2015 Nov 03; Vol. 13 (5), pp. 1046-58.Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247

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  • 1-10 of  45 results for ""Smoothened Receptor""