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Academic Journal

Design, synthesis, and evaluation of (2S,4R)-Ketoconazole sulfonamide analogs as potential treatments for Metabolic Syndrome.

  • Authors : Blass BE; Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, 3307 N Broad Street, Philadelphia, PA 19140, USA. Electronic address: .; Iyer P

Subjects: Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/*chemistry ; Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/*pharmacology ; Ketoconazole/Ketoconazole/Ketoconazole/*analogs & derivatives

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2016 Dec 01; Vol. 26 (23), pp. 5825-5829. Date of Electronic Publication: 2016 Oct 10.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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A simple construction of electrochemical liver microsomal bioreactor for rapid drug metabolism and inhibition assays.

  • Authors : Walgama C; †Department of Chemistry, Oklahoma State University, Stillwater, Oklahoma 74078, United States.; Nerimetla R

Subjects: Bioreactors* ; Electrochemical Techniques*; Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/*pharmacology

  • Source: Analytical chemistry [Anal Chem] 2015; Vol. 87 (9), pp. 4712-8. Date of Electronic Publication: 2015 Apr 22.Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Effects of cytochrome P450 inhibitors and inducers on the metabolism and pharmacokinetics of ospemifene.

  • Authors : Lehtinen T; Clinical Research Services Turku, University of Turku and Turku University Hospital, Turku, Finland.; Tolonen A

Subjects: Cytochrome P-450 Enzyme Inhibitors*; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*administration & dosage ; Estrogen Receptor Modulators/Estrogen Receptor Modulators/Estrogen Receptor Modulators/*pharmacokinetics

  • Source: Biopharmaceutics & drug disposition [Biopharm Drug Dispos] 2013 Oct; Vol. 34 (7), pp. 387-95. Date of Electronic Publication: 2013 Aug 15.Publisher: Wiley Country of Publication: England NLM ID: 7911226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-081X

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Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1.

  • Authors : Chenge JT; From the Manchester Institute of Biotechnology, School of Chemistry, University of Manchester, 131 Princess Street, Manchester M1 7DN, United Kingdom.; Duyet LV

Subjects: Antifungal Agents/Antifungal Agents/Antifungal Agents/*chemistry ; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*antagonists & inhibitors ; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*chemistry

  • Source: The Journal of biological chemistry [J Biol Chem] 2017 Jan 27; Vol. 292 (4), pp. 1310-1329. Date of Electronic Publication: 2016 Dec 08.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

A novel nonsense mutation in androgen receptor confers resistance to CYP17 inhibitor treatment in prostate cancer.

  • Authors : Han D; Center for Personalized Cancer Therapy, University of Massachusetts Boston, Boston, Massachusetts 02125, USA.; Gao S

Subjects: Codon, Nonsense*; Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/*therapeutic use ; Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/*therapeutic use

  • Source: Oncotarget [Oncotarget] 2017 Jan 24; Vol. 8 (4), pp. 6796-6808.Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain.

  • Authors : Ruparel S; Department of Endodontics, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.; Green D

Subjects: Cytochrome P-450 Enzyme Inhibitors*; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology ; Inflammation/Inflammation/Inflammation/*drug therapy

  • Source: Molecular pain [Mol Pain] 2012 Sep 24; Vol. 8, pp. 73. Date of Electronic Publication: 2012 Sep 24.Publisher: Sage Publications Inc Country of Publication: United States NLM ID: 101242662 Publication Model: Electronic Cited Medium: Internet ISSN:

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Inhibition of triclabendazole metabolism in vitro by ketoconazole increases disruption to the tegument of a triclabendazole-resistant isolate of Fasciola hepatica.

  • Authors : Devine C; Parasite Therapeutics Group, School of Biological Sciences, Medical Biology Centre, The Queen's University of Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK.; Brennan GP

Subjects: Cytochrome P-450 Enzyme Inhibitors* ; Fasciola hepatica*/Fasciola hepatica*/Fasciola hepatica*/drug effects ; Fasciola hepatica*/Fasciola hepatica*/Fasciola hepatica*/enzymology

  • Source: Parasitology research [Parasitol Res] 2011 Oct; Vol. 109 (4), pp. 981-95. Date of Electronic Publication: 2011 Mar 26.Publisher: Springer International Country of Publication: Germany NLM ID: 8703571 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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The effects of concurrent administration of cytochrome P-450 inhibitors on the pharmacokinetics of oral methadone in healthy dogs.

  • Authors : Kukanich B; Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA. ; Kukanich KS

Subjects: Cytochrome P-450 Enzyme Inhibitors*; Analgesics, Opioid/Analgesics, Opioid/Analgesics, Opioid/*pharmacokinetics ; Chloramphenicol/Chloramphenicol/Chloramphenicol/*pharmacology

  • Source: Veterinary anaesthesia and analgesia [Vet Anaesth Analg] 2011 May; Vol. 38 (3), pp. 224-30.Publisher: Elsevier Country of Publication: United States NLM ID: 100956422 Publication Model: Print Cited Medium: Internet ISSN: 1467-2995

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Academic Journal

Structural basis of human CYP51 inhibition by antifungal azoles.

  • Authors : Strushkevich N; Structural Genomics Consortium, University of Toronto, 101 College Street, Toronto, Ontario, Canada. ; Usanov SA

Subjects: Cytochrome P-450 Enzyme Inhibitors*; Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*chemistry ; Econazole/Econazole/Econazole/*pharmacology

  • Source: Journal of molecular biology [J Mol Biol] 2010 Apr 09; Vol. 397 (4), pp. 1067-78. Date of Electronic Publication: 2010 Feb 10.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Ketoconazole increases fingolimod blood levels in a drug interaction via CYP4F2 inhibition.

  • Authors : Kovarik JM; Novartis Pharma, Building WSJ 210.427, 4002 Basel, Switzerland.; Dole K

Subjects: Cytochrome P-450 Enzyme Inhibitors*; Immunosuppressive Agents/Immunosuppressive Agents/Immunosuppressive Agents/*pharmacokinetics ; Ketoconazole/Ketoconazole/Ketoconazole/*pharmacology

  • Source: Journal of clinical pharmacology [J Clin Pharmacol] 2009 Feb; Vol. 49 (2), pp. 212-8. Date of Electronic Publication: 2008 Dec 31.Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0091-2700 (Print)

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  • 1-10 of  136 results for ""Cytochrome P-450 Enzyme Inhibitors""