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Academic Journal

Utilization of Sodium Nitroprusside as an Intestinal Permeation Enhancer for Lipophilic Drug Absorption Improvement in the Rat Proximal Intestine.

  • Authors : Kishimoto H; Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan.; Miyazaki K

Subjects: Cell Membrane Permeability/Cell Membrane Permeability/Cell Membrane Permeability/*drug effects ; Intestinal Absorption/Intestinal Absorption/Intestinal Absorption/*drug effects ; Intestinal Mucosa/Intestinal Mucosa/Intestinal Mucosa/*drug effects

  • Source: Molecules (Basel, Switzerland) [Molecules] 2021 Oct 22; Vol. 26 (21). Date of Electronic Publication: 2021 Oct 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

A focus on critical aspects of uptake and transport of milk-derived extracellular vesicles across the Caco-2 intestinal barrier model.

  • Authors : Roerig J; Pharmaceutical Technology, Institute of Pharmacy, Medical Faculty, Leipzig University, Germany. Electronic address: .; Schiller L

Subjects: Milk* ; Permeability*; Drug Delivery Systems/Drug Delivery Systems/Drug Delivery Systems/*methods

  • Source: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 9109778 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Absorption-Enhancing Mechanisms of Capryol 90, a Novel Absorption Enhancer, for Improving the Intestinal Absorption of Poorly Absorbed Drugs: Contributions to Trans- or Para-Cellular Pathways.

  • Authors : Ukai H; Department of Biopharmaceutics, Kyoto Pharmaceutical University, 5 Nakauchi-cho, Misasagi, Yamashina-Ku, Kyoto, 607-8414, Japan.; Imanishi A

Subjects: Alendronate/Alendronate/Alendronate/*metabolism ; Intestinal Absorption/Intestinal Absorption/Intestinal Absorption/*drug effects ; Intestinal Mucosa/Intestinal Mucosa/Intestinal Mucosa/*drug effects

  • Source: Pharmaceutical research [Pharm Res] 2020 Nov 23; Vol. 37 (12), pp. 248. Date of Electronic Publication: 2020 Nov 23.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Metabolite profiling of natural substances in human: in vitro study from fecal bacteria to colon carcinoma cells (Caco-2).

  • Authors : Racova Z; Department of Pharmacology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Czech Republic. Electronic address: .; Anzenbacherova E

Subjects: Metabolome*; Bacteria/Bacteria/Bacteria/*metabolism ; Feces/Feces/Feces/*microbiology

  • Source: The Journal of nutritional biochemistry [J Nutr Biochem] 2020 Nov; Vol. 85, pp. 108482. Date of Electronic Publication: 2020 Aug 12.Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The Impact of Breast Cancer Resistance Protein (BCRP/ABCG2) on Drug Transport Across Caco-2 Cell Monolayers.

  • Authors : Kawahara I; Department of Biopharmaceutics, Kyoto Pharmaceutical University, Kyoto, Japan (I.K., S.N., A.Y.) and Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Ritsumeikan University, Shiga, Japan (Y.K., T.F.).; Nishikawa S

Subjects: ATP Binding Cassette Transporter, Subfamily G, Member 2/ATP Binding Cassette Transporter, Subfamily G, Member 2/ATP Binding Cassette Transporter, Subfamily G, Member 2/*metabolism ; Intestinal Mucosa/Intestinal Mucosa/Intestinal Mucosa/*metabolism ; Neoplasm Proteins/Neoplasm Proteins/Neoplasm Proteins/*metabolism

  • Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2020 Jun; Vol. 48 (6), pp. 491-498. Date of Electronic Publication: 2020 Mar 19.Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: United States NLM ID: 9421550 Publication Model:

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Academic Journal

A Lipid-Based Nanocarrier Containing Active Vitamin D 3 Ameliorates NASH in Mice via Direct and Intestine-Mediated Effects on Liver Inflammation.

  • Authors : Mu Y; Graduate School of Systems Life Sciences, Kyushu University.; Li J

Subjects: Calcitriol/Calcitriol/Calcitriol/*administration & dosage ; Drug Carriers/Drug Carriers/Drug Carriers/*chemistry ; Hepatitis/Hepatitis/Hepatitis/*drug therapy

  • Source: Biological & pharmaceutical bulletin [Biol Pharm Bull] 2020; Vol. 43 (9), pp. 1413-1420.Publisher: Pharmaceutical Society of Japan Country of Publication: Japan NLM ID: 9311984 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Influence of Pharmaceutical Formulation on the Mucosal Concentration of 5-Aminosalicylic Acid and N-Acetylmesalamine in Japanese Patients with Ulcerative Colitis.

  • Authors : Yamamoto Y; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital.; Department of Clinical Pharmacology and Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kyushu University.

Subjects: Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/*chemistry ; Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/*therapeutic use ; Colitis, Ulcerative/Colitis, Ulcerative/Colitis, Ulcerative/*drug therapy

  • Source: Biological & pharmaceutical bulletin [Biol Pharm Bull] 2019 Jan 01; Vol. 42 (1), pp. 81-86. Date of Electronic Publication: 2018 Oct 24.Publisher: Pharmaceutical Society of Japan Country of Publication: Japan NLM ID: 9311984 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Integrating theoretical and experimental permeability estimations for provisional biopharmaceutical classification: Application to the WHO essential medicines.

  • Authors : Cabrera-Pérez MÁ; Unit of Modeling and Experimental Biopharmaceutics, Centre of Chemical Bioactive, Central University of Las Villas, Santa Clara, 54830, Villa Clara, Cuba.; Department of Pharmacy and Pharmaceutical Technology, University of Valencia, Burjassot, 46100, Valencia, Spain.

Subjects: Models, Biological*; Drugs, Essential/Drugs, Essential/Drugs, Essential/*classification ; Drugs, Essential/Drugs, Essential/Drugs, Essential/*metabolism

  • Source: Biopharmaceutics & drug disposition [Biopharm Drug Dispos] 2018 Jul; Vol. 39 (7), pp. 354-368. Date of Electronic Publication: 2018 Aug 19.Publisher: Wiley Country of Publication: England NLM ID: 7911226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-081X

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Academic Journal

Development of a Caco-2 Cell Line Carrying the Human Intestine-Type CES Expression Profile as a Promising Tool for Ester-Containing Drug Permeability Studies.

  • Authors : Ishizaki Y; Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University.; Furihata T

Subjects: Caco-2 Cells*; Carboxylesterase/Carboxylesterase/Carboxylesterase/*genetics ; Intestinal Mucosa/Intestinal Mucosa/Intestinal Mucosa/*metabolism

  • Source: Biological & pharmaceutical bulletin [Biol Pharm Bull] 2018; Vol. 41 (5), pp. 697-706.Publisher: Pharmaceutical Society of Japan Country of Publication: Japan NLM ID: 9311984 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Inhibiting Cholesterol Absorption During Lactation Programs Future Intestinal Absorption of Cholesterol in Adult Mice.

  • Authors : Dimova LG; Department of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; de Boer JF

Subjects: Adaptation, Physiological*; Cholesterol/Cholesterol/Cholesterol/*metabolism ; Cholesterol, Dietary/Cholesterol, Dietary/Cholesterol, Dietary/*metabolism

  • Source: Gastroenterology [Gastroenterology] 2017 Aug; Vol. 153 (2), pp. 382-385.e3. Date of Electronic Publication: 2017 Apr 22.Publisher: W.B. Saunders Country of Publication: United States NLM ID: 0374630 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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