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Academic Journal

SP1‑mediated ADAMTS5 transcription promotes IL‑1β‑induced chondrocyte injury via Wnt/β‑catenin pathway in osteoarthritis.

  • Authors : Hao X; Department of Teaching Administration, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Xiangyang, Hubei 441000, P.R. China.; Wu X

Subjects: Chondrocytes*/Chondrocytes*/Chondrocytes*/metabolism ; Chondrocytes*/Chondrocytes*/Chondrocytes*/pathology ; Sp1 Transcription Factor*/Sp1 Transcription Factor*/Sp1 Transcription Factor*/metabolism

  • Source: Molecular medicine reports [Mol Med Rep] 2024 Aug; Vol. 30 (2). Date of Electronic Publication: 2024 Jun 28.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

LncRNA MALAT1/MiR-145 Adjusts IL-1β-Induced Chondrocytes Viability and Cartilage Matrix Degradation by Regulating ADAMTS5 in Human Osteoarthritis.

  • Authors : Liu C; Department of Bone and Joint Surgery, The Sixth People's Hospital of Ji'nan City (Zhangqiu People's Hospital affiliated to Jining Medical University), Shandong, China.; Ren S

Subjects: ADAMTS5 Protein/ADAMTS5 Protein/ADAMTS5 Protein/*genetics ; Cartilage, Articular/Cartilage, Articular/Cartilage, Articular/*pathology ; Chondrocytes/Chondrocytes/Chondrocytes/*pathology

  • Source: Yonsei medical journal [Yonsei Med J] 2019 Nov; Vol. 60 (11), pp. 1081-1092.Publisher: Yonsei University Country of Publication: Korea (South) NLM ID: 0414003 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Circ-SPG11 knockdown hampers IL-1β-induced osteoarthritis progression via targeting miR-337-3p/ADAMTS5.

  • Authors : Liu Y; Department of Orthopedics, Shijiazhuang People's Hospital, No. 365 Jianhua South Road, Shijiazhang, Hebei, 050000, People's Republic of China.; Li Q

Subjects: Gene Knockdown Techniques*; ADAMTS5 Protein/ADAMTS5 Protein/ADAMTS5 Protein/*genetics ; ADAMTS5 Protein/ADAMTS5 Protein/ADAMTS5 Protein/*metabolism

  • Source: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2021 Jun 17; Vol. 16 (1), pp. 392. Date of Electronic Publication: 2021 Jun 17.Publisher: BioMed Central Country of Publication: England NLM ID: 101265112 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-799X

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Academic Journal

MicroRNA-92a-3p Regulates Aggrecanase-1 and Aggrecanase-2 Expression in Chondrogenesis and IL-1β-Induced Catabolism in Human Articular Chondrocytes.

  • Authors : Mao G; Department of Joint Surgery, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; Wu P

Subjects: ADAMTS4 Protein/ADAMTS4 Protein/ADAMTS4 Protein/*metabolism ; ADAMTS5 Protein/ADAMTS5 Protein/ADAMTS5 Protein/*metabolism ; Chondrogenesis/Chondrogenesis/Chondrogenesis/*drug effects

  • Source: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology [Cell Physiol Biochem] 2017; Vol. 44 (1), pp. 38-52. Publisher: Cell Physiol Biochem Press GmbH & Co KG Country of Publication: Germany NLM ID: 9113221 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

The IL-1β/AP-1/miR-30a/ADAMTS-5 axis regulates cartilage matrix degradation in human osteoarthritis.

  • Authors : Ji Q; Department of Orthopaedics, General Hospital of Chinese People's Liberation Army, Beijing, 100853, China.; Xu X

Subjects: ADAMTS5 Protein/ADAMTS5 Protein/ADAMTS5 Protein/*genetics ; Cartilage, Articular/Cartilage, Articular/Cartilage, Articular/*metabolism ; Interleukin-1beta/Interleukin-1beta/Interleukin-1beta/*genetics

  • Source: Journal of molecular medicine (Berlin, Germany) [J Mol Med (Berl)] 2016 Jul; Vol. 94 (7), pp. 771-85. Date of Electronic Publication: 2016 Apr 11.Publisher: Springer International Country of Publication: Germany NLM ID: 9504370 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Myrislignan ameliorates the progression of osteoarthritis: An in vitro and in vivo study.

  • Authors : Wang L; Department of Orthopaedics, The Fourth Affiliated Hospital of Soochow University, Suzhou 215028, Jiangsu, China.; Fu X

Subjects: Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/drug therapy ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/pathology ; Chondrocytes*/Chondrocytes*/Chondrocytes*/drug effects

  • Source: International immunopharmacology [Int Immunopharmacol] 2024 Oct 25; Vol. 140, pp. 112887. Date of Electronic Publication: 2024 Aug 07.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mume Fructus reduces interleukin-1 beta-induced cartilage degradation via MAPK downregulation in rat articular chondrocytes.

  • Authors : Park DR; Jaseng Spine and Joint Research Institute, Jaseng Medical Foundation, Gangnam-gu, Seoul, Republic of Korea.; Choi BR

Subjects: Cartilage, Articular*/Cartilage, Articular*/Cartilage, Articular*/drug effects ; Cartilage, Articular*/Cartilage, Articular*/Cartilage, Articular*/metabolism ; Chondrocytes*/Chondrocytes*/Chondrocytes*/drug effects

  • Source: PloS one [PLoS One] 2024 May 08; Vol. 19 (5), pp. e0302906. Date of Electronic Publication: 2024 May 08 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

SNHG5 protects chondrocytes in interleukin-1β-stimulated osteoarthritis via regulating miR-181a-5p/TGFBR3 axis.

  • Authors : Yue Y; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.; Zhibo S

Subjects: Chondrocytes/Chondrocytes/Chondrocytes/*metabolism ; Interleukin-1beta/Interleukin-1beta/Interleukin-1beta/*adverse effects ; MicroRNAs/MicroRNAs/MicroRNAs/*metabolism

  • Source: Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2021 Oct; Vol. 35 (10), pp. e22866. Date of Electronic Publication: 2021 Aug 08.Publisher: Wiley Country of Publication: United States NLM ID: 9717231 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-0461

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Academic Journal

A chondroprotective effect of moracin on IL-1β-induced primary rat chondrocytes and an osteoarthritis rat model through Nrf2/HO-1 and NF-κB axes.

  • Authors : Zhou S; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan, 430060, China. .; Shi J

Subjects: Chondrocytes/Chondrocytes/Chondrocytes/*drug effects ; Heme Oxygenase (Decyclizing)/Heme Oxygenase (Decyclizing)/Heme Oxygenase (Decyclizing)/*metabolism ; Interleukin-1beta/Interleukin-1beta/Interleukin-1beta/*metabolism

  • Source: Food & function [Food Funct] 2020 Sep 23; Vol. 11 (9), pp. 7935-7945.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101549033 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Knockdown of SGK1 alleviates the IL-1β-induced chondrocyte anabolic and catabolic imbalance by activating FoxO1-mediated autophagy in human chondrocytes.

  • Authors : Huang W; Department of Orthopaedics, The First Affiliated Hospital of Anhui Medical University, Hefei, China.; Department of Orthopaedics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.

Subjects: Autophagy*; Chondrocytes/Chondrocytes/Chondrocytes/*pathology ; Forkhead Box Protein O1/Forkhead Box Protein O1/Forkhead Box Protein O1/*metabolism

  • Source: The FEBS journal [FEBS J] 2020 Jan; Vol. 287 (1), pp. 94-107. Date of Electronic Publication: 2019 Jul 31.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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  • 1-10 of  30 results for ""ADAMTS5 Protein""