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Insulin protects acinar cells during pancreatitis by preserving glycolytic ATP supply to calcium pumps.

• Authors : Bruce JIE; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK. .; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA. .

Subjects: Acinar Cells/Acinar Cells/Acinar Cells/*metabolism ; Adenosine Triphosphate/Adenosine Triphosphate/Adenosine Triphosphate/*metabolism ; Calcium/Calcium/Calcium/*metabolism

• Source: Nature communications [Nat Commun] 2021 Jul 19; Vol. 12 (1), pp. 4386. Date of Electronic Publication: 2021 Jul 19.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Endocrine and exocrine pancreas pathologies crosstalk: Insulin regulates the unfolded protein response in pancreatic exocrine acinar cells.

• Authors : Yatchenko Y; Department of Nutrition, Faculty of Health Sciences, Ariel University, 40700, Israel.; Horwitz A

Subjects: Unfolded Protein Response*; Acinar Cells/Acinar Cells/Acinar Cells/*metabolism ; Insulin/Insulin/Insulin/*metabolism

• Source: Experimental cell research [Exp Cell Res] 2019 Feb 15; Vol. 375 (2), pp. 28-35. Date of Electronic Publication: 2019 Jan 06.Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Identification of miRNAs Involved in Reprogramming Acinar Cells into Insulin Producing Cells.

• Authors : Teichenne J; Center of Animal Biotechnology and Gene Therapy, Universitat Autònoma de Barcelona, Bellaterra, Spain.; Department of Biochemistry and Molecular Biology, School of Veterinary Medicine. Universitat Autònoma de Barcelona, Bellaterra, Spain.

Subjects: Adenoviridae* ; Cellular Reprogramming Techniques* ; Transcription Factors*/Transcription Factors*/Transcription Factors*/biosynthesis

• Source: PloS one [PLoS One] 2015 Dec 21; Vol. 10 (12), pp. e0145116. Date of Electronic Publication: 2015 Dec 21 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Lacrimal gland primary acinar cell culture: the role of insulin.

• Authors : Malki LT; Department of Ophthalmology, Otorhinolaryngology and Head & Neck Surgery, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.; Dias AC

Subjects: Acinar Cells/Acinar Cells/Acinar Cells/*cytology ; Insulin/Insulin/Insulin/*pharmacology ; Lacrimal Apparatus/Lacrimal Apparatus/Lacrimal Apparatus/*cytology

• Source: Arquivos brasileiros de oftalmologia [Arq Bras Oftalmol] 2016 Apr; Vol. 79 (2), pp. 105-10.Publisher: Conselho Brasileiro de Oftalmologia Country of Publication: Brazil NLM ID: 0400645 Publication Model: Print Cited Medium: Internet ISSN:

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Insulin degradation by acinar cell proteases creates a dysfunctional environment for human islets before/after transplantation: benefits of α-1 antitrypsin treatment.

• Authors : Loganathan G; Department of Surgery, Schulze Diabetes Institute, University of Minnesota, Minneapolis, MN 55455, USA.; Dawra RK

Subjects: Acinar Cells/Acinar Cells/Acinar Cells/*enzymology ; Insulin/Insulin/Insulin/*metabolism ; Islets of Langerhans/Islets of Langerhans/Islets of Langerhans/*drug effects

• Source: Transplantation [Transplantation] 2011 Dec 15; Vol. 92 (11), pp. 1222-30.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0132144 Publication Model: Print Cited Medium: Internet ISSN:

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Agricola

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Do nonglycaemic effects such as weight loss account for HbA1c lowering with efpeglenatide?: Insights from the AMPLITUDE‐O trial.

• Authors : Gerstein, Hertzel C.; Yang, Mu; Lee, Shun Fu

Subjects: PANCREATIC acinar cells; MAJOR adverse cardiovascular events; REDUCING diets

• Source: Diabetes, Obesity & Metabolism; Dec2024, Vol. 26 Issue 12, p6080-6084, 5p

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Repurposed cancer drug could treat diabetes by nudging pancreatic acinar cells to produce insulin.

Subjects: PANCREATIC acinar cells; ANTINEOPLASTIC agents; INSULINUNIVERSITY of Pittsburgh

• Source: Cancer Weekly; 5/21/2024, p286-286, 1p

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Transgenic Expression of a Single Transcription Factor Pdx1 Induces Transdifferentiation of Pancreatic Acinar Cells to Endocrine Cells in Adult Mice.

• Authors : Miyazaki, Satsuki; Tashiro, Fumi; Miyazaki, Jun-ichi

Subjects: TRANSGENE expression; TRANSCRIPTION factors; PANCREATIC acinar cells

• Source: PLoS ONE; 8/15/2016, Vol. 11 Issue 8, p1-21, 21p

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Generation of insulin-secreting cells from pancreatic acinar cells of animal models of type 1 diabetes.

• Authors : Okuno, Masaaki; Minami, Kohtaro; Okumachi, Akinori

Subjects: PANCREATIC acinar cells; DIABETES; PANCREATIC cytology

• Source: American Journal of Physiology: Endocrinology & Metabolism; Jan2007, Vol. 292, pE158-E165, 8p, 1 Chart, 6 Graphs

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