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Subject : insulin

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Academic Journal

Dipeptidyl peptidase IV inhibition reduces the degradation and clearance of GIP and potentiates its insulinotropic and antihyperglycemic effects in anesthetized pigs.

Authors : Deacon CF; Department of Medical Physiology, The Panum Institute, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark. ; Danielsen P

Subjects: Blood Glucose/Blood Glucose/Blood Glucose/*metabolism ; Dipeptidyl Peptidase 4/Dipeptidyl Peptidase 4/Dipeptidyl Peptidase 4/*metabolism ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology

Source: Diabetes [Diabetes] 2001 Jul; Vol. 50 (7), pp. 1588-97.Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Paracrine regulation of somatostatin secretion by insulin and glucagon in mouse pancreatic islets.

Authors : Svendsen B; NovoNordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. .; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. .

Subjects: Glucagon/Glucagon/Glucagon/*physiology ; Insulin/Insulin/Insulin/*physiology ; Somatostatin/Somatostatin/Somatostatin/*metabolism

Source: Diabetologia [Diabetologia] 2021 Jan; Vol. 64 (1), pp. 142-151. Date of Electronic Publication: 2020 Oct 12.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Enhancing endogenous levels of GLP1 dampens acute olanzapine induced perturbations in lipid and glucose metabolism.

Authors : Medak, Kyle D.; Weber, Alyssa J.; Shamshoum, Hesham

Subjects: HYPERGLYCEMIA; LIPID metabolism; GLUCOSE metabolism

Source: Frontiers in Pharmacology; 3/1/2023, Vol. 14, p01-10, 10p

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Academic Journal

Acute effects on glucose tolerance by neprilysin inhibition in patients with type 2 diabetes.

Authors : Wewer Albrechtsen, Nicolai J.; Møller, Andreas; Martinussen, Christoffer

Subjects: TYPE 2 diabetes; INSULIN; NEPRILYSIN

Source: Diabetes, Obesity & Metabolism; Oct2022, Vol. 24 Issue 10, p2017-2026, 10p

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Academic Journal

13C15N: glucagon-based novel isotope dilution mass spectrometry method for measurement of glucagon metabolism in humans.

Authors : Renuse, Santosh; Benson, Linda M.; Vanderboom, Patrick M.

Subjects: GLUCAGON; MASS spectrometry; ISOTOPE dilution analysis

Source: Clinical Proteomics; 5/19/2022, Vol. 19 Issue 1, p1-11, 11p

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Academic Journal

Neprilysin inhibition improves intravenous but not oral glucose-mediated insulin secretion via GLP-1R signaling in mice with β-cell dysfunction.

Authors : Esser, Nathalie; Mongovin, Stephen M.; Parilla, Jacqueline

Subjects: NEPRILYSIN; INSULIN receptors; ANGIOTENSIN-receptor blockers

Source: American Journal of Physiology: Endocrinology & Metabolism; Mar2022, Vol. 322 Issue 3, p307-318, 12p

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Academic Journal

A role of PLC/PKC-dependent pathway in GLP-1-stimulated insulin secretion.

Authors : Shigeto, Makoto; Cha, Chae; Rorsman, Patrik

Subjects: GLUCAGON-like peptide 1; INSULIN; PROTEIN kinase C

Source: Journal of Molecular Medicine; Apr2017, Vol. 95 Issue 4, p361-368, 8p

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Academic Journal

The insulinotropic effect of exogenous glucagon-like peptide-1 is not affected by acute vagotomy in anaesthetized pigs.

Authors : Veedfald, Simon; Hansen, Marie; Christensen, Louise Wulff

Subjects: INSULIN; GLUCAGON-like peptide 1; VAGOTOMY

Source: Experimental Physiology; Jul2016, Vol. 101 Issue 7, p895-912, 18p

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Academic Journal

Establishment of a Refined Oral Glucose Tolerance Test in Pigs, and Assessment of Insulin, Glucagon and Glucagon-Like Peptide-1 Responses.

Authors : Manell, Elin; Hedenqvist, Patricia; Svensson, Anna

Subjects: GLUCOSE tolerance tests; GLUCAGON-like peptide 1; DIABETES

Source: PLoS ONE; 2/9/2016, Vol. 11 Issue 2, p1-14, 14p

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Academic Journal

The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1.

Authors : Plamboeck, Astrid; Veedfald, Simon; Deacon, Carolyn F.

Subjects: CHOLINERGIC mechanisms; NEURAL transmission; GLUCAGON-like peptide 1

Source: American Journal of Physiology: Regulatory, Integrative & Comparative Physiology; Sep2015, Vol. 309 Issue 5, pR544-R554, 8p

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