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Targeting NF-κB Signaling: Selected Small Molecules Downregulate Pro-Inflammatory Cytokines in Both Food Allergen and LPS-Induced Inflammation.

• Authors : Zlatanova M; Department of Biochemistry, Faculty of Chemistry, University of Belgrade, 11000 Belgrade, Serbia.; Nešić A

Subjects: Lipopolysaccharides* ; Cytokines*/Cytokines*/Cytokines*/metabolism ; NF-kappa B*/NF-kappa B*/NF-kappa B*/metabolism

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 26; Vol. 25 (11). Date of Electronic Publication: 2024 May 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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The progress of small molecules against cannabinoid 2 receptor (CB 2 R).

• Authors : Zhang Q; Hangzhou Medical College, Hangzhou, Zhejiang, China.; Zhao Y

Subjects: Inflammation* ; Cannabinoids*; Humans

• Source: Bioorganic chemistry [Bioorg Chem] 2024 Mar; Vol. 144, pp. 107075. Date of Electronic Publication: 2024 Jan 08.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Agricola

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TNF-α: The shape of small molecules to come?

• Authors : Dömling A; Drug Design Department, University of Groningen, the Netherlands. Electronic address: .; Li X

Subjects: Inflammation*/Inflammation*/Inflammation*/drug therapy ; Inflammation*/Inflammation*/Inflammation*/immunology ; Tumor Necrosis Factor Inhibitors*/Tumor Necrosis Factor Inhibitors*/Tumor Necrosis Factor Inhibitors*/chemistry

• Source: Drug discovery today [Drug Discov Today] 2022 Jan; Vol. 27 (1), pp. 3-7. Date of Electronic Publication: 2021 Jul 03.Publisher: Elsevier Science Ltd. Country of Publication: England NLM ID: 9604391 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Small molecules targeting ubiquitination to control inflammatory diseases.

• Authors : Li ZQ; Institute of Chinese Medical Sciences and State Key Laboratory of Quality Research in Chinese Medicine and, University of Macau, Avenida da Universidade, Taipa, Macao.; Chen X

Subjects: Inflammation/Inflammation/Inflammation/*drug therapy ; Proteins/Proteins/Proteins/*metabolism ; Ubiquitination/Ubiquitination/Ubiquitination/*drug effects

• Source: Drug discovery today [Drug Discov Today] 2021 Oct; Vol. 26 (10), pp. 2414-2422. Date of Electronic Publication: 2021 May 14.Publisher: Elsevier Science Ltd. Country of Publication: England NLM ID: 9604391 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Regulation of the NLRP3 Inflammasome by Post-Translational Modifications and Small Molecules.

• Authors : Seok JK; BK21 PLUS Team, College of Pharmacy, The Catholic University of Korea, Bucheon, South Korea.; Kang HC

Subjects: Inflammasomes/Inflammasomes/Inflammasomes/*immunology ; Inflammation/Inflammation/Inflammation/*immunology ; NLR Family, Pyrin Domain-Containing 3 Protein/NLR Family, Pyrin Domain-Containing 3 Protein/NLR Family, Pyrin Domain-Containing 3 Protein/*immunology

• Source: Frontiers in immunology [Front Immunol] 2021 Feb 02; Vol. 11, pp. 618231. Date of Electronic Publication: 2021 Feb 02 (Print Publication: 2020).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet

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Directed self-assembly of herbal small molecules into sustained release hydrogels for treating neural inflammation.

• Authors : Zheng J; Key Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, College of Chemistry and Chemical Engineering, Central South University, 410083, Changsha, China.; Fan R

Subjects: Anthraquinones/Anthraquinones/Anthraquinones/*administration & dosage ; Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*administration & dosage ; Drug Carriers/Drug Carriers/Drug Carriers/*chemistry

• Source: Nature communications [Nat Commun] 2019 Apr 08; Vol. 10 (1), pp. 1604. Date of Electronic Publication: 2019 Apr 08.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Discovery of an effective anti-inflammatory agent for inhibiting the activation of NF-κB.

• Authors : Yan, Yaoyao¹ (AUTHOR); Lv, Qi¹ (AUTHOR); Zhou, Feilong¹ (AUTHOR)

Subjects: *ANTI-inflammatory agents; *SMALL molecules; *CELLULAR signal transduction

• Source: Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2023, Vol. 38 Issue 1, p1-9. 9p.

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Dl-3-n-Butylphthalide improves lipopolysaccharide-induced depressive-like behavior in rats: involvement of Nrf2 and NF-κB pathways.

• Authors : Yang, Mengqi; Dang, Ruili; Xu, Pengfei

Subjects: SMALL molecules; CELERY; SEEDS

• Source: Psychopharmacology. Sep2018, Vol. 235 Issue 9, p2573-2585. 13p. 1 Diagram, 1 Chart, 5 Graphs.

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Histone acetylation, BET proteins, and periodontal inflammation.

• Authors : Clayton, Nicholas¹ (AUTHOR); Pellei, David¹ (AUTHOR); Lin, Zhao¹ (AUTHOR)

Subjects: *HISTONE acetylation; *SMALL molecules; *TRANSCRIPTION factors

• Source: Molecular Oral Microbiology. Aug2024, Vol. 39 Issue 4, p180-189. 10p.

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