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Academic Journal

Dexamethasone relieves the inflammatory response caused by inguinal hernia meshes through miR-155.

  • Authors : Li Y; Department of General Surgery, The First People's Hospital of Yunnan Province, Xishan District, No. 157, Jinbi Road, Kunming, 650032, Yunnan, China.; Lv Y

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; Dexamethasone*/Dexamethasone*/Dexamethasone*/therapeutic use ; Dexamethasone*/Dexamethasone*/Dexamethasone*/pharmacology

  • Source: Hernia : the journal of hernias and abdominal wall surgery [Hernia] 2024 Aug; Vol. 28 (4), pp. 1113-1119. Date of Electronic Publication: 2024 Mar 16.Publisher: Springer Country of Publication: France NLM ID: 9715168 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1248-9204

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Academic Journal

Schistosoma egg antigens suppress LPS-induced inflammation in human IMR-90 cells by modulation of JAK/STAT1 signaling.

  • Authors : Lee KY; Division of Pulmonary Medicine, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan; Division of Thoracic Medicine, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.

Subjects: Signal Transduction*; Antigens, Helminth/Antigens, Helminth/Antigens, Helminth/*pharmacology ; Fibroblasts/Fibroblasts/Fibroblasts/*drug effects

  • Source: Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi [J Microbiol Immunol Infect] 2021 Jun; Vol. 54 (3), pp. 501-513. Date of Electronic Publication: Publisher: published by Elsevier for the Taiwan Society of Microbiology Country of Publication: England NLM ID: 100956211 Publication Model: Print-Electronic

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Academic Journal

Systemic Jak1 activation provokes hepatic inflammation and imbalanced FGF23 production and cleavage.

  • Authors : Daryadel A; Institute of Physiology, University of Zurich (UZH), and National Center of Competence in Research NCCR Kidney.CH, Zurich, Switzerland.; Ruiz PA

Subjects: Fibroblast Growth Factors/Fibroblast Growth Factors/Fibroblast Growth Factors/*metabolism ; Inflammation/Inflammation/Inflammation/*metabolism ; Janus Kinase 1/Janus Kinase 1/Janus Kinase 1/*metabolism

  • Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Feb; Vol. 35 (2), pp. e21302.Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited

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Academic Journal

Pharmacokinetics, Pharmacodynamics, and Proposed Dosing of the Oral JAK1 and JAK2 Inhibitor Baricitinib in Pediatric and Young Adult CANDLE and SAVI Patients.

  • Authors : Kim H; Lawrence Shulman Scholar, Office of the Clinical Director, and Pediatric Translational Research Branch, NIAMS, NIH, Bethesda, Maryland, USA.; Brooks KM

Subjects: Drug Dosage Calculations* ; Models, Biological*; Autoimmune Diseases/Autoimmune Diseases/Autoimmune Diseases/*drug therapy

  • Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2018 Aug; Vol. 104 (2), pp. 364-373. Date of Electronic Publication: 2017 Dec 08.Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535

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Academic Journal

FOXM1 activates JAK1/STAT3 pathway in human osteoarthritis cartilage cell inflammatory reaction.

  • Authors : Zeng R; Department of Orthopedic Surgery, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China.; Lu X

Subjects: Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects; Cartilage, Articular/Cartilage, Articular/Cartilage, Articular/*pathology ; Forkhead Box Protein M1/Forkhead Box Protein M1/Forkhead Box Protein M1/*metabolism

  • Source: Experimental biology and medicine (Maywood, N.J.) [Exp Biol Med (Maywood)] 2021 Mar; Vol. 246 (6), pp. 644-653. Date of Electronic Publication: 2020 Dec 09.Publisher: Sage Country of Publication: England NLM ID: 100973463 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3699

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Academic Journal

Preclinical characterization of itacitinib (INCB039110), a novel selective inhibitor of JAK1, for the treatment of inflammatory diseases.

Subjects: Azetidines/Azetidines/Azetidines/*pharmacology ; Inflammation/Inflammation/Inflammation/*drug therapy ; Isonicotinic Acids/Isonicotinic Acids/Isonicotinic Acids/*pharmacology

  • Source: European journal of pharmacology [Eur J Pharmacol] 2020 Oct 15; Vol. 885, pp. 173505. Date of Electronic Publication: 2020 Aug 28.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Recent progress and perspective in JAK inhibitors for rheumatoid arthritis: from bench to bedside.

  • Authors : Tanaka Y; The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health Japan, Kitakyushu 807-8555, Japan .

Subjects: Arthritis, Rheumatoid/Arthritis, Rheumatoid/Arthritis, Rheumatoid/*drug therapy ; Inflammation/Inflammation/Inflammation/*drug therapy ; Janus Kinase 1/Janus Kinase 1/Janus Kinase 1/*genetics

  • Source: Journal of biochemistry [J Biochem] 2015 Sep; Vol. 158 (3), pp. 173-9. Date of Electronic Publication: 2015 Jul 07.Publisher: Oxford University Press Country of Publication: England NLM ID: 0376600 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies.

  • Authors : Sanchez GAM; Translational Autoinflammatory Disease Section, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA.; Reinhardt A

Subjects: Azetidines/Azetidines/Azetidines/*therapeutic use ; Hereditary Autoinflammatory Diseases/Hereditary Autoinflammatory Diseases/Hereditary Autoinflammatory Diseases/*drug therapy ; Hereditary Autoinflammatory Diseases/Hereditary Autoinflammatory Diseases/Hereditary Autoinflammatory Diseases/*immunology

  • Source: The Journal of clinical investigation [J Clin Invest] 2018 Jul 02; Vol. 128 (7), pp. 3041-3052. Date of Electronic Publication: 2018 Jun 11.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited

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Academic Journal

A Dual Inhibition, a Better Solution: Development of a JAK1/TYK2 inhibitor.

  • Authors : Menet CJ; Drug Discovery , Confo Therapeutics , Technologiepark 4 , Ghent (Zwijnaarde) 9052 , Belgium.

Subjects: Inflammation/Inflammation/Inflammation/*drug therapy ; Janus Kinase 1/Janus Kinase 1/Janus Kinase 1/*antagonists & inhibitors ; Protein Kinase Inhibitors/Protein Kinase Inhibitors/Protein Kinase Inhibitors/*pharmacology

  • Source: Journal of medicinal chemistry [J Med Chem] 2018 Oct 11; Vol. 61 (19), pp. 8594-8596. Date of Electronic Publication: 2018 Sep 25.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Phytosphingosine derivatives ameliorate skin inflammation by inhibiting NF-κB and JAK/STAT signaling in keratinocytes and mice.

  • Authors : Kim BH; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.; Lee JM

Subjects: Inflammation/Inflammation/Inflammation/*drug therapy ; Janus Kinase 1/Janus Kinase 1/Janus Kinase 1/*metabolism ; Keratinocytes/Keratinocytes/Keratinocytes/*cytology

  • Source: The Journal of investigative dermatology [J Invest Dermatol] 2014 Apr; Vol. 134 (4), pp. 1023-1032. Date of Electronic Publication: 2013 Oct 31.Publisher: Elsevier Country of Publication: United States NLM ID: 0426720 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  151 results for ""Janus Kinase 1""