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CD36 inhibition corrects lipid-FetuinA mediated insulin secretory defects by preventing intracellular lipid accumulation and inflammation in the pancreatic beta cells.

• Authors : Mandal S; Cell Signaling Laboratory, Department of Zoology, Siksha Bhavana (Institute of Science), Visva-Bharati University, Santiniketan 731235, India.; Nag S

Subjects: Insulin-Secreting Cells*/Insulin-Secreting Cells*/Insulin-Secreting Cells*/metabolism ; Insulin-Secreting Cells*/Insulin-Secreting Cells*/Insulin-Secreting Cells*/drug effects ; Insulin-Secreting Cells*/Insulin-Secreting Cells*/Insulin-Secreting Cells*/pathology

• Source: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2025 Feb; Vol. 1871 (2), pp. 167580. Date of Electronic Publication: 2024 Nov 18.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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A novel GPR120-selective agonist promotes insulin secretion and improves chronic inflammation.

• Authors : Yang L; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China.

Subjects: Insulin Secretion*/Insulin Secretion*/Insulin Secretion*/drug effects; Inflammation/Inflammation/Inflammation/*pathology ; Receptors, G-Protein-Coupled/Receptors, G-Protein-Coupled/Receptors, G-Protein-Coupled/*agonists

• Source: Life sciences [Life Sci] 2021 Mar 15; Vol. 269, pp. 119029. Date of Electronic Publication: 2021 Jan 12.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Silencing cyclophilin A improves insulin secretion, reduces cell apoptosis, and alleviates inflammation as well as oxidant stress in high glucose-induced pancreatic β-cells via MAPK/NF-kb signaling pathway.

• Authors : Li T; Department of Health Care Centre, Hainan General Hospital , Haikou, Hainan, China.; Quan H

Subjects: Apoptosis/Apoptosis/Apoptosis/*physiology ; Cyclophilin A/Cyclophilin A/Cyclophilin A/*metabolism ; Glucose/Glucose/Glucose/*pharmacology

• Source: Bioengineered [Bioengineered] 2020 Dec; Vol. 11 (1), pp. 1047-1057.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101581063 Publication Model: Print Cited Medium: Internet ISSN:

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Agricola

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NUPR1 preserves insulin secretion of pancreatic β-cells during inflammatory stress by multiple low-dose streptozotocin and high-fat diet.

• Authors : Päth G; Division of Endocrinology and Diabetology, Department of Medicine II, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Mehana AE

Subjects: DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*physiology ; Diet, High-Fat/Diet, High-Fat/Diet, High-Fat/*adverse effects ; Inflammation/Inflammation/Inflammation/*physiopathology

• Source: American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2020 Aug 01; Vol. 319 (2), pp. E338-E344. Date of Electronic Publication: 2020 Jun 23.Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901226 Publication Model: Print-Electronic Cited Medium:

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Asprosin impairs insulin secretion in response to glucose and viability through TLR4/JNK-mediated inflammation.

• Authors : Lee T; Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea; Department of Surgery, Seoul National University College of Medicine, Seoul, South Korea.

Subjects: Insulin Secretion*; Glucose/Glucose/Glucose/*toxicity ; Inflammation/Inflammation/Inflammation/*metabolism

• Source: Molecular and cellular endocrinology [Mol Cell Endocrinol] 2019 Apr 15; Vol. 486, pp. 96-104. Date of Electronic Publication: 2019 Mar 07.Publisher: North Holland Publishing Country of Publication: Ireland NLM ID: 7500844 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Agricola

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Agricola

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In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice.

• Authors : Sandström J; Department of Physiology, Faculty of Biology and Medicine, University of Lausanne, Rue du Bugnon 7, 1005, Lausanne, Switzerland.; Swiss Centre for Applied Human Toxicology, Basel, Switzerland.

Subjects: Glucocorticoids/Glucocorticoids/Glucocorticoids/*metabolism ; Inflammation/Inflammation/Inflammation/*metabolism ; Insulin Secretion/Insulin Secretion/Insulin Secretion/*drug effects

• Source: Archives of toxicology [Arch Toxicol] 2019 Jun; Vol. 93 (6), pp. 1649-1664. Date of Electronic Publication: 2019 Apr 16.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Agricola

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