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Academic Journal

Identification of poly(rC) binding protein 2 (PCBP2) as a target protein of immunosuppressive agent 15-deoxyspergualin.

  • Authors : Murahashi M; Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.; Simizu S

Subjects: Guanidines/Guanidines/Guanidines/*pharmacology ; Immunosuppressive Agents/Immunosuppressive Agents/Immunosuppressive Agents/*pharmacology ; RNA-Binding Proteins/RNA-Binding Proteins/RNA-Binding Proteins/*antagonists & inhibitors

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2016 Aug 05; Vol. 476 (4), pp. 445-449. Date of Electronic Publication: 2016 May 31.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Gusperimus: immunological mechanism and clinical applications.

  • Authors : Perenyei M; Medical Sciences Division, University of Oxford, Oxford, Lupus and Vasculitis Clinic, Addenbrookes Hospital, Cambridge and Department of Nephrology, Royal Berkshire Hospital, Reading, UK.; Jayne DR

Subjects: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/*drug therapy ; Graft Rejection/Graft Rejection/Graft Rejection/*drug therapy ; Guanidines/Guanidines/Guanidines/*therapeutic use

  • Source: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2014 Oct; Vol. 53 (10), pp. 1732-41. Date of Electronic Publication: 2014 Feb 05.Publisher: Oxford University Press Country of Publication: England NLM ID: 100883501 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Long-term treatment of relapsing Wegener's granulomatosis with 15-deoxyspergualin.

  • Authors : Flossmann O; Department of Nephrology, Royal Berkshire Hospital, Reading, Berkshire RG1 5AN, UK. ; Jayne DR

Subjects: Granulomatosis with Polyangiitis/Granulomatosis with Polyangiitis/Granulomatosis with Polyangiitis/*drug therapy ; Guanidines/Guanidines/Guanidines/*administration & dosage ; Immunosuppressive Agents/Immunosuppressive Agents/Immunosuppressive Agents/*administration & dosage

  • Source: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2010 Mar; Vol. 49 (3), pp. 556-62. Date of Electronic Publication: 2009 Dec 23.Publisher: Oxford University Press Country of Publication: England NLM ID: 100883501 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Treatment of active lupus nephritis with the novel immunosuppressant 15-deoxyspergualin: an open-label dose escalation study.

  • Authors : Lorenz HM; Division of Rheumatology, University Hospital Heidelberg, INF410, 69120 Heidelberg, Germany. ; Schmitt WH

Subjects: Guanidines/Guanidines/Guanidines/*administration & dosage ; Immunosuppressive Agents/Immunosuppressive Agents/Immunosuppressive Agents/*administration & dosage ; Lupus Nephritis/Lupus Nephritis/Lupus Nephritis/*drug therapy

  • Source: Arthritis research & therapy [Arthritis Res Ther] 2011 Mar 01; Vol. 13 (2), pp. R36. Date of Electronic Publication: 2011 Mar 01.Publisher: BioMed Central Country of Publication: England NLM ID: 101154438 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-6362

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Academic Journal

Chemical conjugation of DeltaF508-CFTR corrector deoxyspergualin to transporter human serum albumin enhances its ability to rescue Cl- channel functions.

  • Authors : Norez C; Laboratory of Molecular Pathology, Laboratory of Clinical Chemistry and Hematology, University Hospital of Verona, Verona, Italy.; Pasetto M

Subjects: Point Mutation*; Cystic Fibrosis/Cystic Fibrosis/Cystic Fibrosis/*drug therapy ; Cystic Fibrosis Transmembrane Conductance Regulator/Cystic Fibrosis Transmembrane Conductance Regulator/Cystic Fibrosis Transmembrane Conductance Regulator/*metabolism

  • Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2008 Aug; Vol. 295 (2), pp. L336-47. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Prolonged treatment of refractory Wegener's granulomatosis with 15-deoxyspergualin: an open study in seven patients.

  • Authors : Schmitt WH; Fifth Medical Clinic, University Hospital Mannheim, Heidelberg University,Theodor-Kutzer-Ufer 1-3, D-68135 Mannheim, Germany. ; Birck R

Subjects: Granulomatosis with Polyangiitis/Granulomatosis with Polyangiitis/Granulomatosis with Polyangiitis/*drug therapy ; Guanidines/Guanidines/Guanidines/*administration & dosage ; Immunosuppressive Agents/Immunosuppressive Agents/Immunosuppressive Agents/*administration & dosage

  • Source: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2005 Jun; Vol. 20 Publisher: Oxford University Press Country of Publication: England NLM ID: 8706402 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Control of cyclosporine A-induced tumor progression using 15-deoxyspergualin for rat cardiac transplantation.

  • Authors : Ohsawa I; Division of Organ Replacement Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan.; Uemoto S

Subjects: Cyclosporine/Cyclosporine/Cyclosporine/*adverse effects ; Guanidines/Guanidines/Guanidines/*therapeutic use ; Heart Transplantation/Heart Transplantation/Heart Transplantation/*adverse effects

  • Source: Transplantation [Transplantation] 2007 Aug 15; Vol. 84 (3), pp. 424-8.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0132144 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Effect of certain immunosuppressants on non-specific immunity cells in murine corneal grafts: study on early phases after transplantation.

  • Authors : Bysterská P; Institute of Pharmacology, First Faculty of Medicine, Charles University, Prague, Czech Republic.; Svozílková P

Subjects: Corneal Transplantation*; Cornea/Cornea/Cornea/*drug effects ; Graft Rejection/Graft Rejection/Graft Rejection/*prevention & control

  • Source: Physiological research [Physiol Res] 2007; Vol. 56 (5), pp. 603-610. Date of Electronic Publication: 2006 Dec 19.Publisher: Published for the Institute of Physiology of the Czechoslovak Academy of Sciences by Academia, Pub. House of the Academy Country of Publication: Czech Republic

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Academic Journal

In vivo effects of cyclic administration of 15-deoxyspergualin on leucocyte function in patients with Wegener's granulomatosis.

  • Authors : Kälsch AI; Department of Clinical Chemistry, University Hospital Mannheim, University of Heidelberg, Germany. ; Schmitt WH

Subjects: CD4-Positive T-Lymphocytes/CD4-Positive T-Lymphocytes/CD4-Positive T-Lymphocytes/*drug effects ; Granulomatosis with Polyangiitis/Granulomatosis with Polyangiitis/Granulomatosis with Polyangiitis/*immunology ; Guanidines/Guanidines/Guanidines/*pharmacology

  • Source: Clinical and experimental immunology [Clin Exp Immunol] 2006 Dec; Vol. 146 (3), pp. 455-62.Publisher: Oxford University Press Country of Publication: England NLM ID: 0057202 Publication Model: Print Cited Medium: Print ISSN: 0009-9104

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Academic Journal

Monotherapy with LF 15-0195, an analogue of 15-deoxyspergualin, significantly prolongs renal allograft survival in monkeys.

  • Authors : Yang H; Department of Surgery, The University of Western Ontario, London, Ontario, Canada.; Chen G

Subjects: Kidney Transplantation*; Graft Survival/Graft Survival/Graft Survival/*drug effects ; Guanidines/Guanidines/Guanidines/*pharmacology

  • Source: Transplantation [Transplantation] 2003 Apr 27; Vol. 75 (8), pp. 1166-71.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0132144 Publication Model: Print Cited Medium: Print ISSN:

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