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Academic Journal

Physicochemical characteristics of human IgG Fc fragments that expose regulatory rheumatoid factor neoepitopes and may show promise as antirheumatic agents.

  • Authors : Sidorov A; Udmurt Federal Research Center UB RAS, Izhevsk, Russian Federation.; Department of Immunology and Cell Biology, Udmurt State University, Izhevsk, Russian Federation.

Subjects: Antirheumatic Agents/Antirheumatic Agents/Antirheumatic Agents/*immunology ; Epitopes/Epitopes/Epitopes/*immunology ; Immunoglobulin Fc Fragments/Immunoglobulin Fc Fragments/Immunoglobulin Fc Fragments/*immunology

  • Source: Biotechnology and applied biochemistry [Biotechnol Appl Biochem] 2020 Mar; Vol. 67 (2), pp. 287-293. Date of Electronic Publication: 2020 Feb 19.Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8609465 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Long-term efficacy, safety and immunogenicity in patients with rheumatoid arthritis continuing on an etanercept biosimilar (LBEC0101) or switching from reference etanercept to LBEC0101: an open-label extension of a phase III multicentre, randomised, double-blind, parallel-group study.

  • Authors : Park MC; Division of Rheumatology, Yonsei University College of Medicine, Seoul, South Korea.; Matsuno H

Subjects: Antirheumatic Agents/Antirheumatic Agents/Antirheumatic Agents/*therapeutic use ; Arthritis, Rheumatoid/Arthritis, Rheumatoid/Arthritis, Rheumatoid/*drug therapy ; Biosimilar Pharmaceuticals/Biosimilar Pharmaceuticals/Biosimilar Pharmaceuticals/*therapeutic use

  • Source: Arthritis research & therapy [Arthritis Res Ther] 2019 May 21; Vol. 21 (1), pp. 122. Date of Electronic Publication: 2019 May 21.Publisher: BioMed Central Country of Publication: England NLM ID: 101154438 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-6362

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Academic Journal

Phase III, multicentre, double-blind, randomised, parallel-group study to evaluate the similarities between LBEC0101 and etanercept reference product in terms of efficacy and safety in patients with active rheumatoid arthritis inadequately responding to methotrexate.

  • Authors : Matsuno H; Matsuno Clinic for Rheumatic Diseases, Toyama, Japan.; Institute of Medical Science, Tokyo Medical University, Tokyo, Japan.

Subjects: Antirheumatic Agents/Antirheumatic Agents/Antirheumatic Agents/*therapeutic use ; Arthritis, Rheumatoid/Arthritis, Rheumatoid/Arthritis, Rheumatoid/*drug therapy ; Biosimilar Pharmaceuticals/Biosimilar Pharmaceuticals/Biosimilar Pharmaceuticals/*therapeutic use

  • Source: Annals of the rheumatic diseases [Ann Rheum Dis] 2018 Apr; Vol. 77 (4), pp. 488-494. Date of Electronic Publication: 2017 Dec 19.Publisher: BMJ Country of Publication: England NLM ID: 0372355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2060

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Academic Journal

Efficacy and safety of tregalizumab in patients with rheumatoid arthritis and an inadequate response to methotrexate: results of a phase IIb, randomised, placebo-controlled trial.

Subjects: Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/*administration & dosage ; Antirheumatic Agents/Antirheumatic Agents/Antirheumatic Agents/*administration & dosage ; Arthritis, Rheumatoid/Arthritis, Rheumatoid/Arthritis, Rheumatoid/*drug therapy

  • Source: Annals of the rheumatic diseases [Ann Rheum Dis] 2018 Apr; Vol. 77 (4), pp. 495-499. Date of Electronic Publication: 2018 Jan 17.Publisher: BMJ Country of Publication: England NLM ID: 0372355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2060

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Academic Journal

Targeting IgG in Arthritis: Disease Pathways and Therapeutic Avenues.

  • Authors : Nandakumar KS; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510000, China. .; Department of Medical Biochemistry and Biophysics, Karolinska Institute, 17177 Stockholm, Sweden. .

Subjects: Antirheumatic Agents/Antirheumatic Agents/Antirheumatic Agents/*pharmacology ; Arthritis/Arthritis/Arthritis/*etiology ; Arthritis/Arthritis/Arthritis/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2018 Feb 28; Vol. 19 (3). Date of Electronic Publication: 2018 Feb 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Antigenic burden and serum IgG concentrations influence rituximab pharmacokinetics in rheumatoid arthritis patients.

  • Authors : Lioger B; CNRS, GICC UMR 7292, Université François-Rabelais de Tours, Tours, France.; Service de Médecine Interne, CHRU de Tours, Tours, France.

Subjects: Antigens, CD20/Antigens, CD20/Antigens, CD20/*blood ; Antirheumatic Agents/Antirheumatic Agents/Antirheumatic Agents/*pharmacokinetics ; Arthritis, Rheumatoid/Arthritis, Rheumatoid/Arthritis, Rheumatoid/*drug therapy

  • Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2017 Aug; Vol. 83 (8), pp. 1773-1781. Date of Electronic Publication: 2017 Apr 12.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of ASP2408, a Potent Selective T-Cell Costimulation Modulator After Single and Multiple Ascending Doses in Healthy Volunteers and RA Patients.

  • Authors : Zhu T; Astellas Pharma Global Development, Northbrook, IL, USA. .; Keirns J

Subjects: Antirheumatic Agents/Antirheumatic Agents/Antirheumatic Agents/*administration & dosage ; Arthritis, Rheumatoid/Arthritis, Rheumatoid/Arthritis, Rheumatoid/*drug therapy ; CTLA-4 Antigen/CTLA-4 Antigen/CTLA-4 Antigen/*administration & dosage

  • Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2016 Sep; Vol. 5 (5), pp. 408-25. Date of Electronic Publication: 2016 Mar 28.Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Clinical utility of random anti-tumor necrosis factor drug-level testing and measurement of antidrug antibodies on the long-term treatment response in rheumatoid arthritis.

Subjects: Antibodies/Antibodies/Antibodies/*immunology ; Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/*therapeutic use ; Antirheumatic Agents/Antirheumatic Agents/Antirheumatic Agents/*therapeutic use

  • Source: Arthritis & rheumatology (Hoboken, N.J.) [Arthritis Rheumatol] 2015 May; Vol. 67 (8), pp. 2011-9.Publisher: Wiley Country of Publication: United States NLM ID: 101623795 Publication Model: Print Cited Medium: Internet ISSN: 2326-5205

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Academic Journal

Discontinuation of disease-modifying anti-rheumatic drugs and clinical outcomes in the Rheumatoid Arthritis DMARD Intervention and Utilisation Study 2 (RADIUS 2).

Subjects: Antirheumatic Agents/Antirheumatic Agents/Antirheumatic Agents/*administration & dosage ; Arthritis, Rheumatoid/Arthritis, Rheumatoid/Arthritis, Rheumatoid/*drug therapy ; Immunoglobulin G/Immunoglobulin G/Immunoglobulin G/*administration & dosage

  • Source: Clinical and experimental rheumatology [Clin Exp Rheumatol] 2015 May-Jun; Vol. 33 (3), pp. 297-301. Date of Electronic Publication: 2015 Feb 18.Publisher: Clinical And Experimental Rheumatology S.A.S Country of Publication: Italy NLM ID: 8308521 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Significant associations of antidrug antibody levels with serum drug trough levels and therapeutic response of adalimumab and etanercept treatment in rheumatoid arthritis.

  • Authors : Chen DY; Division of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital and Faculty of Medicine, National Yang Ming University, Taichung, Taiwan Institute of Microbiology and Immunology, Chung Shan Medical University, Taichung, Taiwan Institute of Biomedical Science, National Chung Hsing University, Taichung, Taiwan.; Chen YM

Subjects: Antibodies/Antibodies/Antibodies/*blood ; Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/Antibodies, Monoclonal, Humanized/*therapeutic use ; Antirheumatic Agents/Antirheumatic Agents/Antirheumatic Agents/*blood

  • Source: Annals of the rheumatic diseases [Ann Rheum Dis] 2015 Mar; Vol. 74 (3), pp. e16. Date of Electronic Publication: 2014 Jan 17.Publisher: BMJ Country of Publication: England NLM ID: 0372355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2060

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  • 1-10 of  1,369 results for ""Antirheumatic Agents""