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Academic Journal

Antitrypanosomal Activity of Sterol 14α-Demethylase (CYP51) Inhibitors VNI and VFV in the Swiss Mouse Models of Chagas Disease Induced by the Trypanosoma cruzi Y Strain.

  • Authors : Guedes-da-Silva FH; Laboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.; Batista DG

Subjects: 14-alpha Demethylase Inhibitors/14-alpha Demethylase Inhibitors/14-alpha Demethylase Inhibitors/*pharmacology ; Chagas Disease/Chagas Disease/Chagas Disease/*drug therapy ; Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*chemistry

  • Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2017 Mar 24; Vol. 61 (4). Date of Electronic Publication: 2017 Mar 24 (Print Publication: 2017).Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Electronic-Print Cited Medium:

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Academic Journal

Molecular Docking Evaluation of Imidazole Analogues as Potent Candida albicans 14α-Demethylase Inhibitors.

  • Authors : Rani N; Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, India. .; Kumar P

Subjects: 14-alpha Demethylase Inhibitors/14-alpha Demethylase Inhibitors/14-alpha Demethylase Inhibitors/*pharmacology ; Antifungal Agents/Antifungal Agents/Antifungal Agents/*pharmacology ; Candida albicans/Candida albicans/Candida albicans/*drug effects

  • Source: Current computer-aided drug design [Curr Comput Aided Drug Des] 2015; Vol. 11 (1), pp. 8-20.Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101265750 Publication Model: Print Cited Medium: Internet

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Academic Journal

Structural basis for rational design of inhibitors targeting Trypanosoma cruzi sterol 14α-demethylase: two regions of the enzyme molecule potentiate its inhibition.

  • Authors : Friggeri L; Department of Biochemistry, School of Medicine, Vanderbilt University , Nashville, Tennessee 37232, United States.; Hargrove TY

Subjects: 14-alpha Demethylase Inhibitors/14-alpha Demethylase Inhibitors/14-alpha Demethylase Inhibitors/*chemistry ; Carbamates/Carbamates/Carbamates/*chemistry ; Imidazoles/Imidazoles/Imidazoles/*chemistry

  • Source: Journal of medicinal chemistry [J Med Chem] 2014 Aug 14; Vol. 57 (15), pp. 6704-17. Date of Electronic Publication: 2014 Jul 29.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Dialkylimidazole inhibitors of Trypanosoma cruzi sterol 14α-demethylase as anti-Chagas disease agents.

Subjects: 14-alpha Demethylase Inhibitors/14-alpha Demethylase Inhibitors/14-alpha Demethylase Inhibitors/*therapeutic use ; Chagas Disease/Chagas Disease/Chagas Disease/*drug therapy ; Imidazoles/Imidazoles/Imidazoles/*pharmacology

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2013 Dec 01; Vol. 23 (23), pp. 6492-9. Date of Electronic Publication: 2013 Aug 12.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

In vitro and in vivo studies of the antiparasitic activity of sterol 14α-demethylase (CYP51) inhibitor VNI against drug-resistant strains of Trypanosoma cruzi.

  • Authors : Soeiro Mde N; Laboratório de Biologia Celular do IOC, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil. ; de Souza EM

Subjects: 14-alpha Demethylase Inhibitors/14-alpha Demethylase Inhibitors/14-alpha Demethylase Inhibitors/*pharmacology ; Chagas Disease/Chagas Disease/Chagas Disease/*drug therapy ; Imidazoles/Imidazoles/Imidazoles/*pharmacology

  • Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2013 Sep; Vol. 57 (9), pp. 4151-63. Date of Electronic Publication: 2013 Jun 17.Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Design, synthesis and antifungal activity of some new imidazole and triazole derivatives.

  • Authors : Rezaei Z; Department of Medicinal Chemistry, Shiraz University of Medical Sciences, Iran. ; Khabnadideh S

Subjects: Drug Design*; 14-alpha Demethylase Inhibitors/14-alpha Demethylase Inhibitors/14-alpha Demethylase Inhibitors/*chemical synthesis ; Antifungal Agents/Antifungal Agents/Antifungal Agents/*chemical synthesis

  • Source: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2011 Oct; Vol. 344 (10), pp. 658-65. Date of Electronic Publication: 2011 Aug 25.Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Different Therapeutic Outcomes of Benznidazole and VNI Treatments in Different Genders in Mouse Experimental Models of Trypanosoma cruzi Infection.

  • Authors : Guedes-da-Silva FH; Laboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.; Batista DG

Subjects: 14-alpha Demethylase Inhibitors/14-alpha Demethylase Inhibitors/14-alpha Demethylase Inhibitors/*pharmacology ; Chagas Disease/Chagas Disease/Chagas Disease/*drug therapy ; Imidazoles/Imidazoles/Imidazoles/*pharmacology

  • Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2015 Dec; Vol. 59 (12), pp. 7564-70. Date of Electronic Publication: 2015 Sep 28.Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

[Treatment of trichomoniasis vaginalis with imidazole derivatives. Comparative study of other trichomonicides].

Subjects: 14-alpha Demethylase Inhibitors* ; Antifungal Agents* ; Antiparasitic Agents*

  • Source: Hellenike iatrike [Hell Iatr] 1963 May; Vol. 32, pp. 523-8.Publisher: Helliniki Iatriki Country of Publication: Greece NLM ID: 0373002 Publication Model: Print Cited Medium: Print ISSN: 0258-2694 (Print)

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Academic Journal

[EFFECT OF IMIDAZOLE DERIVATIVES ON PYRUVATE DEHYDROGENASE IN MUSCLE TISSUE].

Subjects: 14-alpha Demethylase Inhibitors* ; Birds* ; Imidazoles*

  • Source: Biokhimiia (Moscow, Russia) [Biokhimiia] 1964 Nov-Dec; Vol. 29, pp. 1170-6.Publisher: Izdatelstvo Nauka Country of Publication: Russia (Federation) NLM ID: 0372667 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

[Studies on anti-neoplastic preparations from benzyl imidazole derivatives].

Subjects: 14-alpha Demethylase Inhibitors* ; Antifungal Agents* ; Antineoplastic Agents*

  • Source: Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1957 Aug; Vol. 44 (8), pp. 93-5.Publisher: Administrativnoia Zdaniia Minzdrava Sssr Country of Publication: Russia (Federation) NLM ID: 0370627 Publication Model: Print Cited Medium:

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  • 1-10 of  20 results for ""14-alpha Demethylase Inhibitors""