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  • 1-10 of  26 results for ""Liver-Specific Organic Anion Transporter 1""

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Academic Journal

Atorvastatin induces bile acid-synthetic enzyme Cyp7a1 by suppressing FXR signaling in both liver and intestine in mice.

  • Authors : Fu ZD; Departments of Pharmacology, Toxicology, and Therapeutics University of Kansas Medical Center, Kansas City, KS 66160 Department of Pharmacology, Harbin Medical University (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China), Harbin, Heilongjiang Province, People's Republic of China 150081.; Cui JY

Subjects: Cholesterol 7-alpha-Hydroxylase/Cholesterol 7-alpha-Hydroxylase/Cholesterol 7-alpha-Hydroxylase/*metabolism ; Cytochrome P-450 Enzyme Inducers/Cytochrome P-450 Enzyme Inducers/Cytochrome P-450 Enzyme Inducers/*pharmacology ; Heptanoic Acids/Heptanoic Acids/Heptanoic Acids/*pharmacology

  • Source: Journal of lipid research [J Lipid Res] 2014 Dec; Vol. 55 (12), pp. 2576-86. Date of Electronic Publication: 2014 Oct 02.Publisher: Elsevier Country of Publication: United States NLM ID: 0376606 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Chemically induced mouse liver tumors are resistant to treatment with atorvastatin.

  • Authors : Braeuning A; Institute of Experimental and Clinical Pharmacology and Toxicology, Department of Toxicology, University of Tuebingen, Wilhelmstr, 56, Tuebingen 72074, Germany. .; Bucher P

Subjects: Drug Resistance, Neoplasm*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Heptanoic Acids/Heptanoic Acids/Heptanoic Acids/*pharmacology

  • Source: BMC cancer [BMC Cancer] 2014 Oct 15; Vol. 14, pp. 766. Date of Electronic Publication: 2014 Oct 15.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

No impact of SLCO1B1 521T>C, 388A>G and 411G>A polymorphisms on response to statin therapy in the Greek population.

  • Authors : Giannakopoulou E; Laboratory of Pharmacology, Medical School, Democritus University of Thrace, Dragana Campus, 68100, Alexandroupolis, Greece.; Ragia G

Subjects: Polymorphism, Single Nucleotide*; Heptanoic Acids/Heptanoic Acids/Heptanoic Acids/*therapeutic use ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/Hydroxymethylglutaryl-CoA Reductase Inhibitors/Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use

  • Source: Molecular biology reports [Mol Biol Rep] 2014 Jul; Vol. 41 (7), pp. 4631-8. Date of Electronic Publication: 2014 Mar 26.Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4978

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Academic Journal

The SLCO1B1 c.521T>C polymorphism is associated with dose decrease or switching during statin therapy in the Rotterdam Study.

  • Authors : de Keyser CE; Departments of aEpidemiology bInternal Medicine, Erasmus Medical Center, Rotterdam cDrug Safety Unit, The Health Care Inspectorate dDepartment of Hospital Pharmacy, Pharmacy Foundation of The Hague Hospitals - HAGA eNetherlands Consortium of Healthy Aging, The Hague fDepartment of Pharmacoepidemiology & Clinical Pharmacotherapy, Utrecht University, Utrecht gDepartment of Clinical Pharmacy, St Antonius Hospital Nieuwegein, Nieuwegein hDepartment of Hospital Pharmacy, Pharmacy Foundation of Haarlem Hospitals, Haarlem, The Netherlands iDepartment of Molecular Genetics, Pharmacogenetics and Hormone Research, Bicêtre Hospital, Paris, France.; Peters BJ

Subjects: Anticholesteremic Agents/Anticholesteremic Agents/Anticholesteremic Agents/*therapeutic use ; Heptanoic Acids/Heptanoic Acids/Heptanoic Acids/*therapeutic use ; Hypercholesterolemia/Hypercholesterolemia/Hypercholesterolemia/*drug therapy

  • Source: Pharmacogenetics and genomics [Pharmacogenet Genomics] 2014 Jan; Vol. 24 (1), pp. 43-51.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101231005 Publication Model: Print Cited Medium: Internet

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Academic Journal

Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein.

  • Authors : Higgins JW; Drug Disposition (J.W.H., J.Q.B., A.B.K., M.J.Z.-G.) and Global Statistical Sciences (J.R.M.), Lilly Research Laboratories, Indianapolis, Indiana; and Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina (J.K.F., P.C.S., M.J.Z.-G.).

Subjects: Heptanoic Acids/Heptanoic Acids/Heptanoic Acids/*pharmacokinetics ; Organic Anion Transporters/Organic Anion Transporters/Organic Anion Transporters/*metabolism ; Organic Anion Transporters, Sodium-Independent/Organic Anion Transporters, Sodium-Independent/Organic Anion Transporters, Sodium-Independent/*metabolism

  • Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2014 Jan; Vol. 42 (1), pp. 182-92. Date of Electronic Publication: Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: United States NLM ID: 9421550 Publication Model:

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Academic Journal

Do MDR1 and SLCO1B1 polymorphisms influence the therapeutic response to atorvastatin? A study on a cohort of Egyptian patients with hypercholesterolemia.

  • Authors : Shabana MF; Department of Pharmacology, Faculty of Medicine, Fayoum University, Fayoum, Egypt.; Mishriki AA

Subjects: ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/*genetics ; Anticholesteremic Agents/Anticholesteremic Agents/Anticholesteremic Agents/*therapeutic use ; Heptanoic Acids/Heptanoic Acids/Heptanoic Acids/*therapeutic use

  • Source: Molecular diagnosis & therapy [Mol Diagn Ther] 2013 Oct; Vol. 17 (5), pp. 299-309.Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 101264260 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Clinical and pharmacogenetic predictors of circulating atorvastatin and rosuvastatin concentrations in routine clinical care.

  • Authors : DeGorter MK; Department of Medicine, The University of Western Ontario, London, Canada.; Tirona RG

Subjects: Fluorobenzenes/Fluorobenzenes/Fluorobenzenes/*therapeutic use ; Heptanoic Acids/Heptanoic Acids/Heptanoic Acids/*therapeutic use ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/Hydroxymethylglutaryl-CoA Reductase Inhibitors/Hydroxymethylglutaryl-CoA Reductase Inhibitors/*therapeutic use

  • Source: Circulation. Cardiovascular genetics [Circ Cardiovasc Genet] 2013 Aug; Vol. 6 (4), pp. 400-8. Date of Electronic Publication: 2013 Jul 22.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101489144 Publication Model: Print-Electronic Cited Medium:

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Report

[Myopathy due to deficiency of desaminase myoadenilate induced by atorvastatine].

Subjects: AMP Deaminase/AMP Deaminase/AMP Deaminase/*deficiency ; Heptanoic Acids/Heptanoic Acids/Heptanoic Acids/*adverse effects ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/Hydroxymethylglutaryl-CoA Reductase Inhibitors/Hydroxymethylglutaryl-CoA Reductase Inhibitors/*adverse effects Adenosine monophosphate deaminase deficiency

  • Source: Medicina clinica [Med Clin (Barc)] 2013 Jun 18; Vol. 140 (12), pp. 565-7. Date of Electronic Publication: 2013 Jan 18.Publisher: Elsevier España Country of Publication: Spain NLM ID: 0376377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Lack of association between SLCO1B1 polymorphism and the lipid-lowering effects of atorvastatin and simvastatin in Chinese individuals.

  • Authors : Fu Q; Department of Pharmacology, School of Medicine, Zhengzhou University, 100 Science Road, Zhengzhou 450001, China.; Li YP

Subjects: Polymorphism, Single Nucleotide*; Asian People/Asian People/Asian People/*genetics ; Heptanoic Acids/Heptanoic Acids/Heptanoic Acids/*therapeutic use

  • Source: European journal of clinical pharmacology [Eur J Clin Pharmacol] 2013 Jun; Vol. 69 (6), pp. 1269-74. Date of Electronic Publication: 2012 Dec 22.Publisher: Springer Country of Publication: Germany NLM ID: 1256165 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1041

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Academic Journal

The influence of oral antidiabetic drugs on cellular drug uptake mediated by hepatic OATP family members.

  • Authors : Klatt S; Institute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.; Fromm MF

Subjects: Heptanoic Acids/Heptanoic Acids/Heptanoic Acids/*pharmacokinetics ; Hypoglycemic Agents/Hypoglycemic Agents/Hypoglycemic Agents/*pharmacology ; Organic Anion Transporters/Organic Anion Transporters/Organic Anion Transporters/*metabolism

  • Source: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2013 Apr; Vol. 112 (4), pp. 244-50. Date of Electronic Publication: 2012 Dec 06.Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843

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  • 1-10 of  26 results for ""Liver-Specific Organic Anion Transporter 1""