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Academic Journal

HNF4A and HNF1A exhibit tissue specific target gene regulation in pancreatic beta cells and hepatocytes.

  • Authors : Ng NHJ; Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore, 138673, Singapore.; Ghosh S

Subjects: Hepatocyte Nuclear Factor 4*/Hepatocyte Nuclear Factor 4*/Hepatocyte Nuclear Factor 4*/metabolism ; Hepatocyte Nuclear Factor 4*/Hepatocyte Nuclear Factor 4*/Hepatocyte Nuclear Factor 4*/genetics ; Hepatocyte Nuclear Factor 1-alpha*/Hepatocyte Nuclear Factor 1-alpha*/Hepatocyte Nuclear Factor 1-alpha*/metabolism Mason-Type Diabetes

  • Source: Nature communications [Nat Commun] 2024 Jun 22; Vol. 15 (1), pp. 4288. Date of Electronic Publication: 2024 Jun 22.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

TCF7 is not essential for glucose homeostasis in mice.

  • Authors : Kaur KD; Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, University of Toronto, Toronto, ON, M5G1X5, Canada.; Wong CK

Subjects: Blood Glucose/Blood Glucose/Blood Glucose/*metabolism ; Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/*metabolism ; Hepatocytes/Hepatocytes/Hepatocytes/*metabolism

  • Source: Molecular metabolism [Mol Metab] 2021 Jun; Vol. 48, pp. 101213. Date of Electronic Publication: 2021 Mar 17.Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101605730 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Acetaminophen-induced reduction in glutathione-S-transferase A1 in hepatocytes: A role for hepatic nuclear factor 1α and its response element.

  • Authors : Li Y; College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, China.; Hao B

Subjects: Acetaminophen/Acetaminophen/Acetaminophen/*adverse effects ; Analgesics, Non-Narcotic/Analgesics, Non-Narcotic/Analgesics, Non-Narcotic/*adverse effects ; Glutathione Transferase/Glutathione Transferase/Glutathione Transferase/*metabolism

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2019 Aug 13; Vol. 516 (1), pp. 251-257. Date of Electronic Publication: 2019 Jun 20.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Conversion of hepatoma cells to hepatocyte-like cells by defined hepatocyte nuclear factors.

  • Authors : Cheng Z; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital/Institute, the Second Military Medical University, Shanghai, China.; He Z

Subjects: Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*metabolism ; Cellular Reprogramming/Cellular Reprogramming/Cellular Reprogramming/*genetics ; Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/*metabolism

  • Source: Cell research [Cell Res] 2019 Feb; Vol. 29 (2), pp. 124-135. Date of Electronic Publication: 2018 Dec 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9425763 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Liraglutide downregulates hepatic LDL receptor and PCSK9 expression in HepG2 cells and db/db mice through a HNF-1a dependent mechanism.

  • Authors : Yang SH; Division of Dyslipidemia, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, BeiLiShi Road 167, Beijing, 100037, China.; Department of Cardiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China.

Subjects: Diabetes Mellitus/Diabetes Mellitus/Diabetes Mellitus/*drug therapy ; Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/*metabolism ; Hepatocytes/Hepatocytes/Hepatocytes/*drug effects

  • Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2018 Apr 04; Vol. 17 (1), pp. 48. Date of Electronic Publication: 2018 Apr 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840

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Academic Journal

MicroRNA-337-3p controls hepatobiliary gene expression and transcriptional dynamics during hepatic cell differentiation.

  • Authors : Demarez C; Université catholique de Louvain, de Duve Institute, Brussels, Belgium.; Gérard C

Subjects: Gene Expression Regulation, Developmental*; Cell Differentiation/Cell Differentiation/Cell Differentiation/*genetics ; Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/*genetics

  • Source: Hepatology (Baltimore, Md.) [Hepatology] 2018 Jan; Vol. 67 (1), pp. 313-327. Date of Electronic Publication: 2017 Nov 16.Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet

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Deletion of HNF1α in hepatocytes results in fatty liver-related hepatocellular carcinoma in mice.

  • Authors : Ni Q; Department of Endocrinology, Changzheng Hospital, Second Military Medical University, Shanghai, China.; Ding K

Subjects: Gene Deletion*; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*genetics ; Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/*deficiency

  • Source: FEBS letters [FEBS Lett] 2017 Jul; Vol. 591 (13), pp. 1947-1957. Date of Electronic Publication: 2017 Jun 19.Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 0155157 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Generation of metabolically functioning hepatocytes from human pluripotent stem cells by FOXA2 and HNF1α transduction.

  • Authors : Takayama K; Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan.; Inamura M

Subjects: Embryonic Stem Cells/Embryonic Stem Cells/Embryonic Stem Cells/*cytology ; Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/*genetics ; Hepatocyte Nuclear Factor 3-beta/Hepatocyte Nuclear Factor 3-beta/Hepatocyte Nuclear Factor 3-beta/*genetics

  • Source: Journal of hepatology [J Hepatol] 2012 Sep; Vol. 57 (3), pp. 628-36. Date of Electronic Publication: 2012 May 29.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A concerted action of HNF4alpha and HNF1alpha links hepatitis B virus replication to hepatocyte differentiation.

  • Authors : Quasdorff M; Molecular Infectiology at the Center for Molecular Medicine Cologne, Institute for Medical Microbiology, Goldenfelsstr. 19-21, 50935 Cologne, Germany.; Hösel M

Subjects: Cell Differentiation/Cell Differentiation/Cell Differentiation/*physiology ; Hepatitis B virus/Hepatitis B virus/Hepatitis B virus/*physiology ; Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/Hepatocyte Nuclear Factor 1-alpha/*metabolism

  • Source: Cellular microbiology [Cell Microbiol] 2008 Jul; Vol. 10 (7), pp. 1478-90. Date of Electronic Publication: 2008 Mar 11.Publisher: Hindawi Country of Publication: India NLM ID: 100883691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1462-5822

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Academic Journal

Suppression of C/EBPalpha expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression.

  • Authors : Yamasaki H; Department of Biology, Faculty of Science, Shizuoka University, 836 Oya, Surugaku, Shizuoka City, Shizuoka 422-8529, Japan.; Sada A

Subjects: Gene Expression Regulation, Developmental*; Bile Ducts/Bile Ducts/Bile Ducts/*cytology ; CCAAT-Enhancer-Binding Protein-alpha/CCAAT-Enhancer-Binding Protein-alpha/CCAAT-Enhancer-Binding Protein-alpha/*metabolism

  • Source: Development (Cambridge, England) [Development] 2006 Nov; Vol. 133 (21), pp. 4233-43. Date of Electronic Publication: 2006 Oct 04.Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Print

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  • 1-10 of  58 results for ""Hepatocyte Nuclear Factor 1-alpha""