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Academic Journal

CRISPR-Cas9 globin editing can induce megabase-scale copy-neutral losses of heterozygosity in hematopoietic cells.

  • Authors : Boutin J; Bordeaux University, Bordeaux, France.; INSERM U1035, Biotherapy of Genetic Diseases, Inflammatory disorders and Cancers, Bordeaux, France.

Subjects: CRISPR-Cas Systems* ; Sequence Deletion*; Gene Editing/Gene Editing/Gene Editing/*methods

  • Source: Nature communications [Nat Commun] 2021 Aug 13; Vol. 12 (1), pp. 4922. Date of Electronic Publication: 2021 Aug 13.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Plasmodium falciparum malaria skews globin gene expression balance in in-vitro haematopoietic stem cell culture system: Its implications in malaria associated anemia.

  • Authors : Pathak V; Department of Haematogenetics, National Institute of Immunohaematology (ICMR), KEM Hospital, Parel 400012, Mumbai, India.; Colah R

Subjects: Anemia/Anemia/Anemia/*etiology ; Gene Expression Regulation/Gene Expression Regulation/Gene Expression Regulation/*genetics ; Globins/Globins/Globins/*genetics

  • Source: Experimental parasitology [Exp Parasitol] 2018 Feb; Vol. 185, pp. 29-38. Date of Electronic Publication: 2018 Jan 05.Publisher: Academic Press Country of Publication: United States NLM ID: 0370713 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Prostaglandin E 2 Increases Lentiviral Vector Transduction Efficiency of Adult Human Hematopoietic Stem and Progenitor Cells.

  • Authors : Heffner GC; bluebird bio, Inc., 60 Binney Street, Cambridge, MA 02142, USA. Electronic address: .; Bonner M

Subjects: Transduction, Genetic*; Dinoprostone/Dinoprostone/Dinoprostone/*metabolism ; Genetic Vectors/Genetic Vectors/Genetic Vectors/*genetics

  • Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2018 Jan 03; Vol. 26 (1), pp. 320-328. Date of Electronic Publication: 2017 Oct 05.Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Hematopoietic stem/progenitor cells express myoglobin and neuroglobin: adaptation to hypoxia or prevention from oxidative stress?

  • Authors : D'Aprile A; Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.; Scrima R

Subjects: Gene Expression*; Globins/Globins/Globins/*genetics ; Hematopoietic Stem Cells/Hematopoietic Stem Cells/Hematopoietic Stem Cells/*metabolism

  • Source: Stem cells (Dayton, Ohio) [Stem Cells] 2014 May; Vol. 32 (5), pp. 1267-77.Publisher: Oxford University Press Country of Publication: England NLM ID: 9304532 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Parallel assessment of globin lentiviral transfer in induced pluripotent stem cells and adult hematopoietic stem cells derived from the same transplanted β-thalassemia patient.

  • Authors : Tubsuwan A; CEA, Institute of Emerging Diseases and Innovative Therapies (iMETI), Fontenay aux Roses, France; INSERM U962 and University Paris Sud 11

Subjects: Hematopoietic Stem Cell Transplantation* ; Transduction, Genetic*; Globins/Globins/Globins/*genetics

  • Source: Stem cells (Dayton, Ohio) [Stem Cells] 2013 Sep; Vol. 31 (9), pp. 1785-94.Publisher: Oxford University Press Country of Publication: England NLM ID: 9304532 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Stem cell engineering for the treatment of severe hemoglobinopathies.

  • Authors : Sadelain M; Center for Cell Engineering, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. ; Boulad F

Subjects: Tissue Engineering*; Hematopoietic Stem Cell Transplantation/Hematopoietic Stem Cell Transplantation/Hematopoietic Stem Cell Transplantation/*methods ; Hematopoietic Stem Cells/Hematopoietic Stem Cells/Hematopoietic Stem Cells/*cytology

  • Source: Current molecular medicine [Curr Mol Med] 2008 Nov; Vol. 8 (7), pp. 690-7.Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 101093076 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin.

  • Authors : Hanna J; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.; Wernig M

Subjects: Cellular Reprogramming* ; Hematopoietic Stem Cell Transplantation*; Anemia, Sickle Cell/Anemia, Sickle Cell/Anemia, Sickle Cell/*therapy

  • Source: Science (New York, N.Y.) [Science] 2007 Dec 21; Vol. 318 (5858), pp. 1920-3. Date of Electronic Publication: 2007 Dec 06.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic

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Academic Journal

Lineage-specific transcription factors in multipotent hematopoietic progenitors: a little bit goes a long way.

  • Authors : Bottardi S; Maisonneuve-Rosemont Hospital Research Center, Maisonneuve-Rosemont Hospital and Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada.; Ghiam AF

Subjects: Cell Lineage*; Hematopoietic Stem Cells/Hematopoietic Stem Cells/Hematopoietic Stem Cells/*metabolism ; Transcription Factors/Transcription Factors/Transcription Factors/*metabolism

  • Source: Cell cycle (Georgetown, Tex.) [Cell Cycle] 2007 May 02; Vol. 6 (9), pp. 1035-9. Date of Electronic Publication: 2007 May 29.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101137841 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The gamma-globin gene promoter progressively demethylates as the hematopoietic stem progenitor cells differentiate along the erythroid lineage in baboon fetal liver and adult bone marrow.

  • Authors : Singh M; Jesse Brown VA Medical Center, Chicago, IL 60612, USA. ; Lavelle D

Subjects: DNA Methylation*; Cell Differentiation/Cell Differentiation/Cell Differentiation/*genetics ; Cell Lineage/Cell Lineage/Cell Lineage/*genetics

  • Source: Experimental hematology [Exp Hematol] 2007 Jan; Vol. 35 (1), pp. 48-55.Publisher: Elsevier Science Inc Country of Publication: Netherlands NLM ID: 0402313 Publication Model: Print Cited Medium: Print ISSN: 0301-472X

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Academic Journal

Everolimus is a potent inducer of erythroid differentiation and gamma-globin gene expression in human erythroid cells.

  • Authors : Zuccato C; GenTech-for-Thal, Department of Biochemistry and Molecular Biology, University of Ferrara, Ferrara, Italy.; Bianchi N

Subjects: Globins/Globins/Globins/*genetics ; Hematopoietic Stem Cells/Hematopoietic Stem Cells/Hematopoietic Stem Cells/*drug effects ; Immunosuppressive Agents/Immunosuppressive Agents/Immunosuppressive Agents/*pharmacology

  • Source: Acta haematologica [Acta Haematol] 2007; Vol. 117 (3), pp. 168-76. Date of Electronic Publication: 2006 Dec 05.Publisher: Karger Country of Publication: Switzerland NLM ID: 0141053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1421-9662

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  • 1-10 of  103 results for ""Globins genetics""