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Academic Journal

K Ca channel targeting impairs DNA repair and invasiveness of patient-derived glioblastoma stem cells in culture and orthotopic mouse xenografts which only in part is predictable by K Ca expression levels.

  • Authors : Ganser K; Department of Radiation Oncology, University Hospital of Tübingen, Tübingen, Germany.; Stransky N

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/pathology ; Glioblastoma*/Glioblastoma*/Glioblastoma*/metabolism ; Glioblastoma*/Glioblastoma*/Glioblastoma*/genetics

  • Source: International journal of cancer [Int J Cancer] 2024 Nov 15; Vol. 155 (10), pp. 1886-1901. Date of Electronic Publication: 2024 Jun 27.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

[ 18 F]AlF-NOTA-PCP2: a novel PET/CT tracer for enhanced PD-L1 heterogeneity imaging and comparative analysis with [ 18 F]AlF-NOTA-WL12 in glioblastoma xenografts.

  • Authors : Wang Y; Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, Shandong, 250117, China.; Zhang Y

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/diagnostic imaging ; Glioblastoma*/Glioblastoma*/Glioblastoma*/metabolism ; Positron Emission Tomography Computed Tomography*

  • Source: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2024 Sep; Vol. 51 (11), pp. 3161-3175. Date of Electronic Publication: 2024 May 07.Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts.

  • Authors : Yabo YA; NORLUX Neuro-Oncology Laboratory, Department of Cancer Research, Luxembourg Institute of Health (LIH), L-1210, Luxembourg, Luxembourg.; Department of Life Sciences and Medicine, Faculty of Science, Technology and Medicine (FSTM), University of Luxembourg, L-4367, Belvaux, Luxembourg.

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/genetics ; Glioblastoma*/Glioblastoma*/Glioblastoma*/metabolism ; Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/genetics

  • Source: Genome medicine [Genome Med] 2024 Apr 02; Vol. 16 (1), pp. 51. Date of Electronic Publication: 2024 Apr 02.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Academic Journal

Magnetic resonance imaging-guided intracranial resection of glioblastoma tumors in patient-derived orthotopic xenografts leads to clinically relevant tumor recurrence.

  • Authors : Oudin A; NORLUX Neuro-Oncology Laboratory, Department of Cancer Research, Luxembourg Institute of Health (LIH), 6A, Rue Nicolas-Ernest Barblé, Luxembourg, L-1210, Luxembourg.; Moreno-Sanchez PM

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/diagnostic imaging ; Glioblastoma*/Glioblastoma*/Glioblastoma*/surgery ; Glioblastoma*/Glioblastoma*/Glioblastoma*/pathology

  • Source: BMC cancer [BMC Cancer] 2024 Jan 02; Vol. 24 (1), pp. 3. Date of Electronic Publication: 2024 Jan 02.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

Establishing Brain Tumor Stem Cell Culture from Patient Brain Tumors and Imaging Analysis of Patient-Derived Xenografts.

  • Authors : Mahmoudian E; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada.; Brain and Mind Research Institute, University of Ottawa, Ottawa, ON, Canada.

Subjects: Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/pathology ; Glioblastoma*/Glioblastoma*/Glioblastoma*/pathology; Humans

  • Source: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2024; Vol. 2736, pp. 177-192.Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029

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Academic Journal

DHODH inhibition impedes glioma stem cell proliferation, induces DNA damage, and prolongs survival in orthotopic glioblastoma xenografts.

  • Authors : Spina R; Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA.; Mills I

Subjects: Glioblastoma*/Glioblastoma*/Glioblastoma*/drug therapy ; Glioblastoma*/Glioblastoma*/Glioblastoma*/genetics ; Glioblastoma*/Glioblastoma*/Glioblastoma*/metabolism

  • Source: Oncogene [Oncogene] 2022 Dec; Vol. 41 (50), pp. 5361-5372. Date of Electronic Publication: 2022 Nov 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Real-time evaluation of glioblastoma growth in patient-specific zebrafish xenografts.

  • Authors : Almstedt E; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.; Rosén E

Subjects: Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/pathology ; Glioblastoma*/Glioblastoma*/Glioblastoma*/pathology; Animals

  • Source: Neuro-oncology [Neuro Oncol] 2022 May 04; Vol. 24 (5), pp. 726-738.Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Preclinical modeling in glioblastoma patient-derived xenograft (GBM PDX) xenografts to guide clinical development of lisavanbulin-a novel tumor checkpoint controller targeting microtubules.

  • Authors : Burgenske DM; Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA.; Talele S

Subjects: Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/pathology ; Glioblastoma*/Glioblastoma*/Glioblastoma*/pathology; Animals

  • Source: Neuro-oncology [Neuro Oncol] 2022 Mar 12; Vol. 24 (3), pp. 384-395.Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice.

  • Authors : Cudalbu C; CIBM Center for Biomedical Imaging, Lausanne, Switzerland.; Animal Imaging and Technology, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

Subjects: Brain Neoplasms/Brain Neoplasms/Brain Neoplasms/*genetics ; Glioblastoma/Glioblastoma/Glioblastoma/*genetics; Adult

  • Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2021 Aug 04; Vol. 9 (1), pp. 133. Date of Electronic Publication: 2021 Aug 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960

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Academic Journal

Doxorubicin Delivered via ApoE-Directed Reduction-Sensitive Polymersomes Potently Inhibit Orthotopic Human Glioblastoma Xenografts in Nude Mice.

  • Authors : Ouyang J; Department of Neurosurgery, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, People's Republic of China.; Jiang Y

Subjects: Cell Transformation, Neoplastic*; Apolipoproteins E/Apolipoproteins E/Apolipoproteins E/*metabolism ; Doxorubicin/Doxorubicin/Doxorubicin/*chemistry

  • Source: International journal of nanomedicine [Int J Nanomedicine] 2021 Jun 15; Vol. 16, pp. 4105-4115. Date of Electronic Publication: 2021 Jun 15 (Print Publication: 2021).Publisher: DOVE Medical Press Country of Publication: New Zealand NLM ID: 101263847 Publication Model: eCollection Cited Medium: Internet ISSN:

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