Search Results

Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer.

• Authors : Saha, Supriya K.; Parachoniak, Christine A.; Llovet, Josep M.

Subjects: ISOCITRATE dehydrogenase; LIVER cancer; MUTANT proteins

• Source: Nature. 9/4/2014, Vol. 513 Issue 7516, p110-114. 5p. 4 Graphs.

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Reports from Forschungszentrum Julich GmbH Add New Data to Research in Business [Preparation and Preclinical Evaluation of 18F-Labeled Olutasidenib Derivatives for Non-Invasive Detection of Mutated Isocitrate Dehydrogenase 1 (mIDH1)].

Subjects: ISOCITRATE dehydrogenase; ORGANIC compounds

• Source: Clinical Oncology Week; 9/10/2024, p1191-1191, 1p

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New Research on Cholangiocarcinoma from Zhejiang University School of Medicine Summarized (Differential isocitrate dehydrogenase 1 and isocitrate dehydrogenase 2 mutation-related landscape in intrahepatic cholangiocarcinoma).

Subjects: ISOCITRATE dehydrogenase; CHOLANGIOCARCINOMA; BIOMOLECULES

• Source: Gastroenterology Week; 6/24/2024, p862-862, 1p

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Study Findings from Northwestern University Feinberg School of Medicine Provide New Insights into Isocitrate Dehydrogenase 2 Inhibitors (Differentiation Syndrome in a Patient With NSCLC Harboring IDH2 Mutation Treated With Enasidenib: Case...).

Subjects: ISOCITRATE dehydrogenase; ACUTE myeloid leukemia; GAIN-of-function mutations

• Source: Drug Week; 10/8/2024, p3769-3769, 1p

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Researchers from IRCCS Humanitas Research Hospital Describe Findings in Astrocytomas (Dissecting the Prognostic Signature of Patients With Astrocytoma Isocitrate Dehydrogenase-mutant Grade 4: a Large Multicenter, Retrospective Study).

Subjects: TELOMERASE reverse transcriptase; ISOCITRATE dehydrogenase; ORGANIC compounds

• Source: Genomics & Genetics Weekly; 9/20/2024, p1396-1396, 1p

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Metabolism: IDH2 drives cancer in vivo.

• Authors : Lokody, Isabel

Subjects: *ISOCITRATE dehydrogenase; *GENETIC mutation; *LABORATORY mice

• Source: Nature Reviews Cancer. Nov2013, Vol. 13 Issue 11, p756-757. 2p.

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Recent Studies from University of Ulsan College of Medicine Add New Data to Glioblastomas (Mapping tumor habitats in isocitrate dehydrogenase -wild type glioblastoma: Integrating MRI, pathologic, and RNA data from the Ivy Glioblastoma Atlas...).

Subjects: ISOCITRATE dehydrogenase; MAGNETIC resonance imaging; REPORTERS & reporting

• Source: Clinical Oncology Week; 10/8/2024, p1393-1393, 1p

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Reports from University of Alabama Birmingham Describe Recent Advances in Acute Myeloid Leukemia [Isocitrate Dehydrogenase (Idh) 1 and 2 Mutations Predict Better Outcome In Patients With Acute Myeloid Leukemia Undergoing Allogeneic Hematopoietic...].

Subjects: ACUTE myeloid leukemia; ISOCITRATE dehydrogenase; HEMATOPOIETIC stem cell transplantationUNIVERSITY of Alabama (Tuscaloosa, Ala.)

• Source: Hematology Week; 9/9/2024, p526-526, 1p

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Research Conducted at Sun Yat-sen University Has Provided New Information about Glioblastomas (Role of Histogram Features On Arterial Spin Labeling Perfusion Magnetic Resonance Imaging In Identifying Isocitrate Dehydrogenase Genotypes and...).

Subjects: MAGNETIC resonance angiography; ISOCITRATE dehydrogenase; SPIN labels

• Source: Clinical Oncology Week; 8/5/2024, p1042-1042, 1p

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Leiden University Medical Center Researchers Provide Details of New Studies and Findings in the Area of Acute Myeloid Leukemia [Hotspot DNA Methyltransferase 3A (DNMT3A) and Isocitrate Dehydrogenase 1 and 2 (IDH1/2) Mutations in...].

Subjects: ACUTE myeloid leukemia; ISOCITRATE dehydrogenase; ACADEMIC medical centers

• Source: Immunotherapy Weekly; 6/11/2024, p1141-1141, 1p

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