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Subject : genetic predisposition to disease
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Academic Journal

Contribution of rare variants to heritability of a disease is much greater than conventionally estimated: modification of allele distribution model.

  • Authors : Nagao Y; Department of Clinical Genetics, Tokai University Hospital, Shimokasuya 143, Isehara, Kanagawa, Japan. .; Department of Laboratory Examination, Takashimadaira Chuo General Hospital, Itabashi, Tokyo, Japan. .

Subjects: Gene Frequency* ; Models, Genetic* ; Genetic Predisposition to Disease*

  • Source: Journal of human genetics [J Hum Genet] 2024 Dec; Vol. 69 (12), pp. 663-668. Date of Electronic Publication: 2024 Aug 20.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 9808008 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Deviation from baseline mutation burden provides powerful and robust rare-variants association test for complex diseases.

  • Authors : Jiang L; Program in Bioinformatics, Zhongshan School of Medicine and The Fifth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.; Research Center of Medical Sciences, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.

Subjects: Genetic Predisposition to Disease* ; Genetic Variation* ; Models, Genetic*

  • Source: Nucleic acids research [Nucleic Acids Res] 2022 Apr 08; Vol. 50 (6), pp. e34.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

A Smoothed Version of the Lassosum Penalty for Fitting Integrated Risk Models Using Summary Statistics or Individual-Level Data.

  • Authors : Hahn G; Harvard T.H. Chan School of Public Health, Harvard University, 677 Huntington Ave, Boston, MA 02115, USA.; Prokopenko D

Subjects: Algorithms* ; Genetic Predisposition to Disease* ; Models, Genetic*

  • Source: Genes [Genes (Basel)] 2022 Jan 06; Vol. 13 (1). Date of Electronic Publication: 2022 Jan 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425

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Academic Journal

IKZF1 Rs4132601 Polymorphism and Susceptibility to Acute Lymphocytic Leukemia in Children: A Meta-analysis.

  • Authors : Wu X; Departments of Pediatric Preventive Health.; Liu M

Subjects: Genetic Predisposition to Disease* ; Models, Genetic* ; Polymorphism, Genetic*

  • Source: Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2022 Jan 01; Vol. 44 (1), pp. e101-e108.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505928 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

GCAEMDA: Predicting miRNA-disease associations via graph convolutional autoencoder.

  • Authors : Li L; School of Cyber Science and Engineering, Qufu Normal University, Qufu, China.; Wang YT

Subjects: Models, Genetic* ; Neural Networks, Computer*; Genetic Predisposition to Disease/Genetic Predisposition to Disease/Genetic Predisposition to Disease/*genetics

  • Source: PLoS computational biology [PLoS Comput Biol] 2021 Dec 10; Vol. 17 (12), pp. e1009655. Date of Electronic Publication: 2021 Dec 10 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Decoding disease: from genomes to networks to phenotypes.

  • Authors : Wong AK; Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY, USA.; Sealfon RSG

Subjects: Genetic Predisposition to Disease* ; Genetic Variation* ; Models, Genetic*

  • Source: Nature reviews. Genetics [Nat Rev Genet] 2021 Dec; Vol. 22 (12), pp. 774-790. Date of Electronic Publication: 2021 Aug 02.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 100962779 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Estimating disease prevalence in large datasets using genetic risk scores.

  • Authors : Evans BD; Department of Mathematics, University of Exeter, North Park Road, Exeter, EX4 4QF, UK.; Living Systems Institute, Centre for Biomedical Modelling and Analysis, University of Exeter, Stocker Road, Exeter, EX4 4QD, UK.

Subjects: Algorithms* ; Models, Genetic*; Diabetes Mellitus, Type 1/Diabetes Mellitus, Type 1/Diabetes Mellitus, Type 1/*genetics

  • Source: Nature communications [Nat Commun] 2021 Nov 08; Vol. 12 (1), pp. 6441. Date of Electronic Publication: 2021 Nov 08.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Evaluating the estimation of genetic correlation and heritability using summary statistics.

  • Authors : Zhang J; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, 44106, USA. .; Schumacher FR

Subjects: Models, Genetic* ; Quantitative Trait, Heritable*; Genetic Predisposition to Disease/Genetic Predisposition to Disease/Genetic Predisposition to Disease/*genetics

  • Source: Molecular genetics and genomics : MGG [Mol Genet Genomics] 2021 Nov; Vol. 296 (6), pp. 1221-1234. Date of Electronic Publication: 2021 Sep 29.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 101093320 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

MHRWR: Prediction of lncRNA-Disease Associations Based on Multiple Heterogeneous Networks.

Subjects: Models, Genetic* ; Neoplasms*/Neoplasms*/Neoplasms*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/metabolism

  • Source: IEEE/ACM transactions on computational biology and bioinformatics [IEEE/ACM Trans Comput Biol Bioinform] 2021 Nov-Dec; Vol. 18 (6), pp. 2577-2585. Date of Electronic Publication: Publisher: IEEE Computer Society Country of Publication: United States NLM ID: 101196755 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Predicting miRNA-disease associations using improved random walk with restart and integrating multiple similarities.

  • Authors : Nguyen VT; Faculty of Information Technology, Hanoi National University of Education, Hanoi, Vietnam.; Faculty of Information Technology, Hanoi University of Industry, 298 Cau Dien Street, Bac Tu Liem District, Hanoi, Vietnam.

Subjects: Algorithms* ; Genetic Predisposition to Disease* ; Models, Genetic*

  • Source: Scientific reports [Sci Rep] 2021 Oct 26; Vol. 11 (1), pp. 21071. Date of Electronic Publication: 2021 Oct 26.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  2,063 results for ""Models, Genetic""