Search Results

P.0428 Alpha-synuclein alters expression levels of immediate early genes in Parkinson's disease associated with mutations in the GBA gene.

• Authors : Basharova, K.¹ (AUTHOR); Bezrukova, A.¹ (AUTHOR); Bogdanova, D.¹ (AUTHOR)

Subjects: *PARKINSON'S disease; *ALPHA-synuclein; *GENETIC mutation

• Source: European Neuropsychopharmacology. 2021 Supplement 1, Vol. 53, pS311-S312. 2p.

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Ambroxol therapy for Parkinson’s disease: Systematic literature review.

• Authors : Maharani, Virgi Mayang¹ ; Wirastuti, Ken²; Silviana, Meyvita²

Subjects: *PARKINSON'S disease; *ALPHA-synuclein; *BASAL ganglia

• Source: Romanian Journal of Neurology. 2023, Vol. 22 Issue 2, p89-92. 4p.

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Lysophosphatidylcholine binds α-synuclein and prevents its pathological aggregation.

• Authors : Zhao, Chunyu^1,2 (AUTHOR); Tu, Jia^1,2 (AUTHOR); Wang, Chuchu^1,2 (AUTHOR)

Subjects: *ALPHA-synuclein; *PARKINSON'S disease; *LIPID metabolism

• Source: National Science Review. Jun2024, Vol. 11 Issue 6, p1-10. 10p.

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The E46K mutation modulates α-synuclein prion replication in transgenic mice.

• Authors : Holec, Sara A. M.¹ (AUTHOR); Lee, Jisoo² (AUTHOR); Oehler, Abby² (AUTHOR)

Subjects: *PRIONS; *ALPHA-synuclein; *MICE

• Source: PLoS Pathogens. 12/1/2022, Vol. 18 Issue 12, p1-22. 22p.

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Combined Assessment of GCase Activity and α-synuclein as a Promising Blood Biomarker for GBA Mutation Carriers.

• Authors : Pasquini, C.¹ (AUTHOR); Avenali, M.^1,2 (AUTHOR); Caminiti, S.P.² (AUTHOR)

Subjects: *ALPHA-synuclein; *BIOMARKERS; *GENETIC mutation

• Source: Parkinsonism & Related Disorders. May2024, Vol. 122, pN.PAG-N.PAG. 1p.

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Alpha-Synuclein Disease Mutations Are Structurally Defective and Locally Affect Membrane Binding.

• Authors : Robotta, Marta¹; Cattani, Julia¹; Martins, Juliana Cristina^1,2

Subjects: *ALPHA-synuclein; *HUMAN proteins; *GENETIC mutation

• Source: Journal of the American Chemical Society. 3/29/2017, Vol. 139 Issue 12, p4254-4257. 4p.

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Serum Uric Acid Level as a Biomarker in Idiopathic and Genetic (p.A53T Alpha-Synuclein Carriers) Parkinson's Disease: Data from the PPMI Study.

• Authors : Koros, Christos; Simitsi, Athina-Maria; Papadimitriou, Dimitra

Subjects: URIC acid; PARKINSON'S disease; ALPHA-synuclein

• Source: Journal of Parkinson's Disease; 2020, Vol. 10 Issue 2, p481-487, 7p

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Nrf2 inducer and cncC overexpression attenuates neurodegeneration due to α-synuclein in Drosophila.

• Authors : Wang, Bing; Liu, Qingqing; Shan, Hongyun

Subjects: PARKINSON'S disease treatment; ALPHA-synuclein; TRANSCRIPTION factors

• Source: Biochemistry & Cell Biology. 2015, Vol. 93 Issue 4, p351-358. 8p.

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Study Results from University of Massachusetts Provide New Insights into Nerve Tissue Proteins (The E46k Mutation Modulates Alpha-synuclein Prion Replication In Transgenic Mice).

Subjects: NERVE tissue proteins; ALPHA-synuclein; TRANSGENIC mice

• Source: Genomics & Genetics Weekly; 3/24/2023, p1800-1800, 1p

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Association between CSF alpha-synuclein seeding activity and genetic status in Parkinson's disease and dementia with Lewy bodies.

• Authors : Brockmann, Kathrin; Quadalti, Corinne; Lerche, Stefanie

Subjects: LEWY body dementia; PARKINSON'S disease; CEREBROSPINAL fluid examination

• Source: Acta Neuropathologica Communications; 10/30/2021, Vol. 9 Issue 1, p1-11, 11p

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