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Academic Journal

Design, synthesis, and characterization of novel fluorogenic substrates of the proprotein convertases furin, PC1/3, PC2, PC5/6, and PC7.

  • Authors : Lam van TV; Institute of Pharmaceutical Chemistry, Philipps University, Marbacher Weg 6, D-35032, Marburg, Germany.; Ivanova T

Subjects: Furin* ; Proprotein Convertases*; Amino Acid Sequence

  • Source: Analytical biochemistry [Anal Biochem] 2022 Oct 15; Vol. 655, pp. 114836. Date of Electronic Publication: 2022 Aug 11.Publisher: Elsevier Country of Publication: United States NLM ID: 0370535 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The Proteolytic Regulation of Virus Cell Entry by Furin and Other Proprotein Convertases.

  • Authors : Izaguirre G; College of Dentistry, University of Illinois at Chicago, Chicago, IL 60612, USA. .

Subjects: Virus Internalization*; Furin/Furin/Furin/*metabolism ; Proprotein Convertases/Proprotein Convertases/Proprotein Convertases/*metabolism

  • Source: Viruses [Viruses] 2019 Sep 09; Vol. 11 (9). Date of Electronic Publication: 2019 Sep 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915

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Academic Journal

In Vivo Analysis of the Contribution of Proprotein Convertases to the Processing of FGF23.

  • Authors : Al Rifai O; Unité de recherche en physiologie moléculaire, Institut de Recherches Cliniques de Montréal, Montréal, QC, Canada.; Programme de biologie moléculaire, Université de Montréal, Montréal, QC, Canada.

Subjects: Fibroblast Growth Factor-23/Fibroblast Growth Factor-23/Fibroblast Growth Factor-23/*metabolism ; Furin/Furin/Furin/*metabolism ; Osteoblasts/Osteoblasts/Osteoblasts/*metabolism

  • Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2021 Jun 04; Vol. 12, pp. 690681. Date of Electronic Publication: 2021 Jun 04 (Print Publication: 2021).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print

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Academic Journal

Targeting proprotein convertases in furin-rich lung cancer cells results in decreased in vitro and in vivo growth.

  • Authors : Bassi DE; Department of Pathology and Histopathology Facility, Fox Chase Cancer Center, Philadelphia, Pennsylvania.; Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.

Subjects: Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*drug therapy ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*administration & dosage ; Furin/Furin/Furin/*metabolism

  • Source: Molecular carcinogenesis [Mol Carcinog] 2017 Mar; Vol. 56 (3), pp. 1182-1188. Date of Electronic Publication: 2016 Sep 22.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8811105 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Granulocyte pro-myeloperoxidase is redundantly processed by proprotein convertase furin and PC7 in HL-60 cells.

Subjects: PROPROTEIN convertases; PROTEIN precursors; MYELOPEROXIDASE

  • Source: Biochemistry & Cell Biology. 2024, Vol. 102 Issue 3, p275-284. 10p.

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Academic Journal

Cleavage of the soluble (pro)renin receptor (sATP6AP2) in the placenta.

  • Authors : Morosin SK; School of Biomedical Sciences and Pharmacy, Priority Research Centre for Reproductive Science, Pregnancy and Reproduction Program, Hunter Medical Research Institute, University of Newcastle, Newcastle, 2300, New South Wales, Australia.; Delforce SJ

Subjects: Furin/Furin/Furin/*metabolism ; Proprotein Convertases/Proprotein Convertases/Proprotein Convertases/*metabolism ; Receptors, Cell Surface/Receptors, Cell Surface/Receptors, Cell Surface/*metabolism

  • Source: Placenta [Placenta] 2020 Nov; Vol. 101, pp. 49-56. Date of Electronic Publication: 2020 Aug 23.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8006349 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Processing of human toll-like receptor 7 by furin-like proprotein convertases is required for its accumulation and activity in endosomes.

  • Authors : Hipp MM; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DU, UK.; Shepherd D

Subjects: Protein Processing, Post-Translational*; Furin/Furin/Furin/*metabolism ; Macrophages/Macrophages/Macrophages/*metabolism

  • Source: Immunity [Immunity] 2013 Oct 17; Vol. 39 (4), pp. 711-21.Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print Cited Medium: Internet ISSN: 1097-4180

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Academic Journal

Ectopically expressed pro-group X secretory phospholipase A2 is proteolytically activated in mouse adrenal cells by furin-like proprotein convertases: implications for the regulation of adrenal steroidogenesis.

  • Authors : Layne JD; From the Department of Pharmacology and Nutritional Sciences, Division of Nutritional Sciences, the Saha Cardiovascular Research Center, and.; Shridas P

Subjects: Adrenal Glands/Adrenal Glands/Adrenal Glands/*metabolism ; Furin/Furin/Furin/*metabolism ; Phospholipases A2, Secretory/Phospholipases A2, Secretory/Phospholipases A2, Secretory/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2015 Mar 20; Vol. 290 (12), pp. 7851-60. Date of Electronic Publication: 2015 Jan 26.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Regulation of the proprotein convertases expression and activity during regenerative angiogenesis: Role of hypoxia-inducible factor (HIF).

  • Authors : Ma J; University of Bordeaux, Allée Geoffroy St Hilaire, 33615 Pessac, France; INSERM, LAMC, UMR 1029, Allée Geoffroy St Hilaire, 33615 Pessac, France.

Subjects: Furin/Furin/Furin/*metabolism ; Hypoxia-Inducible Factor 1/Hypoxia-Inducible Factor 1/Hypoxia-Inducible Factor 1/*metabolism ; Neovascularization, Physiologic/Neovascularization, Physiologic/Neovascularization, Physiologic/*physiology

  • Source: European journal of cell biology [Eur J Cell Biol] 2017 Aug; Vol. 96 (5), pp. 457-468. Date of Electronic Publication: 2017 Jun 12.Publisher: Elsevier Country of Publication: Germany NLM ID: 7906240 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-1298

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Academic Journal

Luteolin restricts dengue virus replication through inhibition of the proprotein convertase furin.

  • Authors : Peng M; School of Chinese Materia Medica, Guangzhou University of Chinese Medicine, Guangzhou 510006, China; Program in Emerging Infectious Disease, Duke-NUS Medical School, Singapore 169857, Singapore.

Subjects: Antiviral Agents/Antiviral Agents/Antiviral Agents/*pharmacology ; Dengue Virus/Dengue Virus/Dengue Virus/*drug effects ; Furin/Furin/Furin/*metabolism

  • Source: Antiviral research [Antiviral Res] 2017 Jul; Vol. 143, pp. 176-185. Date of Electronic Publication: 2017 Apr 05.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8109699 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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