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Modified mRNA-Mediated CCN5 Gene Transfer Ameliorates Cardiac Dysfunction and Fibrosis without Adverse Structural Remodeling.

• Authors : Song MH; College of Life Sciences, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea.; Yoo J

Subjects: CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/genetics ; CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/metabolism ; Fibrosis*

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 06; Vol. 25 (11). Date of Electronic Publication: 2024 Jun 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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WISP-1 Regulates Cardiac Fibrosis by Promoting Cardiac Fibroblasts' Activation and Collagen Processing.

• Authors : Li Z; Translational Health Sciences, Bristol Medical School, University of Bristol, Research Floor Level 7, Bristol Royal Infirmary, Bristol BS2 8HW, UK.; Williams H

Subjects: CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/metabolism ; CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/genetics ; Fibroblasts*/Fibroblasts*/Fibroblasts*/metabolism

• Source: Cells [Cells] 2024 Jun 06; Vol. 13 (11). Date of Electronic Publication: 2024 Jun 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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WNT1-inducible signaling protein-1 mediates TGF-β1-induced renal fibrosis in tubular epithelial cells and unilateral ureteral obstruction mouse models via autophagy.

• Authors : Yang X; Department of Nephrology, Sichuan Academy of Medical Science and Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.; Department of Nephrology, Du Jiang Yan Medical Center, Chengdu, China.

Subjects: Autophagy/Autophagy/Autophagy/*physiology ; CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*metabolism ; Epithelial Cells/Epithelial Cells/Epithelial Cells/*metabolism

• Source: Journal of cellular physiology [J Cell Physiol] 2020 Mar; Vol. 235 (3), pp. 2009-2022. Date of Electronic Publication: 2019 Sep 11.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0050222 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Understanding the Role of CCN Matricellular Proteins in Myocardial Fibrosis.

• Authors : Díez J; Program of Cardiovascular Diseases, Centre for Applied Medical Research, University of Navarra, Pamplona, Spain; Department of Cardiology and Cardiac Surgery, University of Navarra Clinic, Pamplona, Spain. Electronic address: .

Subjects: CCN Intercellular Signaling Proteins* ; Fibrosis*; Cardiomyopathies

• Source: Journal of the American College of Cardiology [J Am Coll Cardiol] 2016 Apr 05; Vol. 67 (13), pp. 1569-1571.Publisher: Elsevier Biomedical Country of Publication: United States NLM ID: 8301365 Publication Model: Print Cited Medium: Internet ISSN:

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CCN5 attenuates profibrotic phenotypes of fibroblasts through the Smad6-CCN2 pathway: Potential role in epidural fibrosis.

• Authors : Xu H; Department of Orthopaedics, The Third Affiliated Hospital (Shaanxi Provincial People's Hospital), Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China.; Liu C

Subjects: CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/CCN Intercellular Signaling Proteins/*metabolism ; Connective Tissue Growth Factor/Connective Tissue Growth Factor/Connective Tissue Growth Factor/*metabolism ; Fibrosis/Fibrosis/Fibrosis/*pathology

• Source: International journal of molecular medicine [Int J Mol Med] 2015 Jul; Vol. 36 (1), pp. 123-9. Date of Electronic Publication: 2015 Apr 21.Publisher: D.A. Spandidos Country of Publication: Greece NLM ID: 9810955 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Research Conducted at Kyoto University Has Provided New Information about CCN Intercellular Signaling Proteins (Deletion of connective tissue growth factor ameliorates peritoneal fibrosis by inhibiting angiogenesis and inflammation)

• Source: Obesity, Fitness & Wellness Week. July 20, 2019, 165

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Studies from Qingdao University Have Provided New Data on CCN Intercellular Signaling Proteins (Critical Role of Cysteine-rich Protein 61 In Mediating the Activation of Renal Fibroblasts)

• Source: Obesity, Fitness & Wellness Week. June 8, 2019, 7579

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The matricellular protein decorin delivered intradermally with coacervate improves wound resolution in the CXCR3‐deficient mouse model of hypertrophic scarring.

• Authors : Sylakowski, Kyle; Hwang, Mintai Peter; Justin, Amritha

Subjects: BIOLOGICAL models; WOUND healing; GROWTH factors

• Source: Wound Repair & Regeneration. Jul2022, Vol. 30 Issue 4, p436-447. 12p.

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Studies Conducted at Aichi Medical University on CCN Intercellular Signaling Proteins Recently Reported (Connective tissue growth factor is correlated with peritoneal lymphangiogenesis)

• Source: Health & Medicine Week. September 20, 2019, 5887

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Investigators at Third Affiliated Hospital of Sun Yat-sen University Have Reported New Data on CCN Intercellular Signaling Proteins (Trimetazidine inhibits cardiac fibrosis by reducing reactive oxygen species and downregulating connective ...)

• Source: Cardiovascular Week. August 12, 2019, 150

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