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Administration of fibrinogen concentrate combined with prothrombin complex maintains hemostasis in children undergoing congenital heart repair (a long-term propensity score-matched study).

• Authors : Velik-Salchner C; Department of Anaesthesiology and Intensive Care Medicine, Medical University of Innsbruck, Innsbruck, Austria.; Tauber H

Subjects: Cardiac Surgical Procedures* ; Fibrinogen*/Fibrinogen*/Fibrinogen*/analysis ; Heart Defects, Congenital*/Heart Defects, Congenital*/Heart Defects, Congenital*/surgery

• Source: Acta anaesthesiologica Scandinavica [Acta Anaesthesiol Scand] 2021 Oct; Vol. 65 (9), pp. 1178-1186. Date of Electronic Publication: 2021 Jul 26.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0370270 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Agricola

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Host fibrinogen drives antimicrobial function in Staphylococcus aureus peritonitis through bacterial-mediated prothrombin activation.

• Authors : Prasad JM; Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH 45229.; Negrón O

Subjects: Fibrinogen/Fibrinogen/Fibrinogen/*metabolism ; Peritonitis/Peritonitis/Peritonitis/*metabolism ; Prothrombin/Prothrombin/Prothrombin/*metabolism

• Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jan 05; Vol. 118 (1). Date of Electronic Publication: 2020 Dec 21.Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Recombinant human prothrombin (MEDI8111) combined with fibrinogen dose-dependently improved survival time and reduced blood loss in a porcine model of dilutional coagulopathy with uncontrolled bleeding.

• Authors : Hansson KM; Bioscience Cardiovascular, Early Cardiovascular, Renal and Metabolism, R&D Biopharmaceuticals, AstraZeneca, Gothenburg, AstraZeneca.; Pehrsson S

Subjects: Blood Coagulation Disorders/Blood Coagulation Disorders/Blood Coagulation Disorders/*drug therapy ; Fibrinogen/Fibrinogen/Fibrinogen/*therapeutic use ; Hemorrhage/Hemorrhage/Hemorrhage/*prevention & control

• Source: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis [Blood Coagul Fibrinolysis] 2019 Jun; Vol. 30 (4), pp. 140-148.Publisher: Lippincott Williams And Wilkins Country of Publication: England NLM ID: 9102551 Publication Model: Print Cited Medium: Internet ISSN:

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Prothrombin and fibrinogen carbonylation: How that can affect the blood clotting.

• Authors : Harutyunyan HA; a Laboratory of biochemical and biophysical investigations, Scientific-Research Centre, Yerevan State Medical University after Mkhitar Heratsi , Yerevan 0025 , Armenia.; b Laboratory of Adenyline Compounds Metabolism, H. Buniatian Institute of Biochemistry, National Academy of Sciences of Republic of Armenia , Yerevan 0025 , Armenia.

Subjects: Blood Coagulation/Blood Coagulation/Blood Coagulation/*physiology ; Fibrinogen/Fibrinogen/Fibrinogen/*metabolism ; Prothrombin/Prothrombin/Prothrombin/*metabolism

• Source: Redox report : communications in free radical research [Redox Rep] 2017 Jul; Vol. 22 (4), pp. 160-165. Date of Electronic Publication: 2016 Jun 27.Publisher: Taylor & Francis Country of Publication: England NLM ID: 9511366 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Antithrombin-resistant prothrombin Yukuhashi mutation also causes thrombomodulin resistance in fibrinogen clotting but not in protein C activation.

• Authors : Takagi Y; Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, 1-1-20, Daiko-Minami, Higashi-ku, Nagoya 461-8673, Japan.; Kato I

Subjects: Mutation*; Antithrombin Proteins/Antithrombin Proteins/Antithrombin Proteins/*metabolism ; Fibrinogen/Fibrinogen/Fibrinogen/*metabolism

• Source: Thrombosis research [Thromb Res] 2014 Oct; Vol. 134 (4), pp. 914-7. Date of Electronic Publication: 2014 Aug 14.Publisher: Pergamon Press Country of Publication: United States NLM ID: 0326377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Whole Blood Thromboelastometry by ROTEM and Thrombin Generation by Genesia According to the Genotype and Clinical Phenotype in Congenital Fibrinogen Disorders.

• Authors : Szanto T; Unit of Coagulation Disorders, Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, University of Helsinki, 00029 HUS Helsinki, Finland.; Research Program in Systems Oncology in Faculty of Medicine, University of Helsinki, 00029 HUS Helsinki, Finland.

Subjects: Afibrinogenemia/Afibrinogenemia/Afibrinogenemia/*blood ; Fibrinogen/Fibrinogen/Fibrinogen/*metabolism ; Thrombelastography/Thrombelastography/Thrombelastography/*methods

• Source: International journal of molecular sciences [Int J Mol Sci] 2021 Feb 25; Vol. 22 (5). Date of Electronic Publication: 2021 Feb 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM)-guided administration of fibrinogen concentrate and prothrombin complex concentrate.

• Authors : Schöchl H; Department of Anaesthesiology and Intensive Care, AUVA Trauma Hospital, Dr Franz-Rehrl-Platz 5, Salzburg, Austria. ; Nienaber U

Subjects: Fibrinogen/Fibrinogen/Fibrinogen/*therapeutic use ; Prothrombin/Prothrombin/Prothrombin/*therapeutic use ; Thrombelastography/Thrombelastography/Thrombelastography/*methods

• Source: Critical care (London, England) [Crit Care] 2010; Vol. 14 (2), pp. R55. Date of Electronic Publication: 2010 Apr 07.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 9801902 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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HSC70 from Haemaphysalis flava (Acari: Ixodidae) exerts anticoagulation activity in vitro.

• Authors : He XM; College of Veterinary Medicine, Hunan Provincial Key Laboratory of Protein Engineering in Animal Vaccines, Hunan Collaborative Innovation Center for Safety Production of Livestock and Poultry, Hunan Agricultural University, Changsha, 410128, China.; Liu L

Subjects: Anticoagulants/Anticoagulants/Anticoagulants/*metabolism ; Fibrinogen/Fibrinogen/Fibrinogen/*metabolism ; HSC70 Heat-Shock Proteins/HSC70 Heat-Shock Proteins/HSC70 Heat-Shock Proteins/*metabolism

• Source: Ticks and tick-borne diseases [Ticks Tick Borne Dis] 2019 Jan; Vol. 10 (1), pp. 170-175. Date of Electronic Publication: 2018 Oct 17.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101522599 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Prohemostatic and antithrombin activities of Ankaferd hemostat are linked to fibrinogen gamma chain and prothrombin by functional proteomic analyses.

• Authors : Ozel-Demiralp D; Proteomics Department, Central Laboratory of Ankara University Biotechnology Institute, Ankara, Turkey. ; Igci N

Subjects: Proteomics*; Antithrombins/Antithrombins/Antithrombins/*pharmacokinetics ; Fibrinogen/Fibrinogen/Fibrinogen/*metabolism

• Source: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis [Clin Appl Thromb Hemost] 2012 Nov; Vol. 18 (6), Publisher: Sage Publications Country of Publication: United States NLM ID: 9508125 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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