Search Results

Display Settings
Results per page: 10
Sort By: Relevance
Filter
  • 1-10 of  811 results for ""Small Molecule Libraries""

Your Filters

Subject : enzyme inhibitors
Reset filters
Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request
Academic Journal

Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening.

  • Authors : Krieger IV; Department of Biochemistry & Biophysics, Texas A&M University, College Station, Texas 77843, United States.; Yalamanchili S

Subjects: Antitubercular Agents*/Antitubercular Agents*/Antitubercular Agents*/chemistry ; Antitubercular Agents*/Antitubercular Agents*/Antitubercular Agents*/pharmacology ; Antitubercular Agents*/Antitubercular Agents*/Antitubercular Agents*/therapeutic use

  • Source: ACS infectious diseases [ACS Infect Dis] 2024 May 10; Vol. 10 (5), pp. 1561-1575. Date of Electronic Publication: 2024 Apr 05.Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list
×
Academic Journal

Perspectives and challenges in developing small molecules targeting purine nucleoside phosphorylase.

  • Authors : Chen Y; Department of Neurology, Laboratory of Neuro-system and Multimorbidity and State Key Laboratory of Biotherapy and Cancer Center and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.; Li Y

Subjects: Purine-Nucleoside Phosphorylase*/Purine-Nucleoside Phosphorylase*/Purine-Nucleoside Phosphorylase*/antagonists & inhibitors ; Purine-Nucleoside Phosphorylase*/Purine-Nucleoside Phosphorylase*/Purine-Nucleoside Phosphorylase*/metabolism ; Enzyme Inhibitors*/Enzyme Inhibitors*/Enzyme Inhibitors*/chemistry

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 May 05; Vol. 271, pp. 116437. Date of Electronic Publication: 2024 Apr 20.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list
×
Academic Journal

Discovery of two non-UDP-mimic inhibitors of O-GlcNAc transferase by screening a DNA-encoded library.

  • Authors : Balsollier C; Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht NL-3508 TB, The Netherlands; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, 1000 Ljubljana, Slovenia.

Subjects: N-Acetylglucosaminyltransferases*/N-Acetylglucosaminyltransferases*/N-Acetylglucosaminyltransferases*/antagonists & inhibitors ; N-Acetylglucosaminyltransferases*/N-Acetylglucosaminyltransferases*/N-Acetylglucosaminyltransferases*/metabolism ; Enzyme Inhibitors*/Enzyme Inhibitors*/Enzyme Inhibitors*/pharmacology

  • Source: Bioorganic chemistry [Bioorg Chem] 2024 Jun; Vol. 147, pp. 107321. Date of Electronic Publication: 2024 Mar 29.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list
×
Academic Journal

Identification of novel plant cysteine oxidase inhibitors from a yeast chemical genetic screen.

Subjects: Arabidopsis Proteins*/Arabidopsis Proteins*/Arabidopsis Proteins*/genetics ; Arabidopsis Proteins*/Arabidopsis Proteins*/Arabidopsis Proteins*/metabolism ; Cysteine Dioxygenase*/Cysteine Dioxygenase*/Cysteine Dioxygenase*/antagonists & inhibitors

  • Source: The Journal of biological chemistry [J Biol Chem] 2023 Dec; Vol. 299 (12), pp. 105366. Date of Electronic Publication: 2023 Oct 19.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

Record details

Read More Add to Saved list
×
Academic Journal

Multi-targeting of K-Ras domains and mutations by peptide and small molecule inhibitors.

  • Authors : Poorebrahim M; Targeted Tumor Vaccines Group, Clinical Cooperation Unit Applied Tumor Immunity, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Abazari MF

Subjects: Enzyme Inhibitors*/Enzyme Inhibitors*/Enzyme Inhibitors*/pharmacology ; Genes, ras* ; Mutation*

  • Source: PLoS computational biology [PLoS Comput Biol] 2022 Apr 26; Vol. 18 (4), pp. e1009962. Date of Electronic Publication: 2022 Apr 26 (Print Publication: 2022).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

Record details

Read Online Read More Add to Saved list
×
Academic Journal

Design, synthesis and biological evaluation studies of novel small molecule ENPP1 inhibitors for cancer immunotherapy.

  • Authors : Gangar M; Aten Porus Lifesciences, Bangalore 560068, India.; Goyal S

Subjects: Immunotherapy*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology

  • Source: Bioorganic chemistry [Bioorg Chem] 2022 Feb; Vol. 119, pp. 105549. Date of Electronic Publication: 2021 Dec 11.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list
×
Academic Journal

Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases.

  • Authors : Healey RD; IGF, University of Montpellier, CNRS, INSERM, Montpellier, 34094, France.; Saied EM

Subjects: Small Molecule Libraries*/Small Molecule Libraries*/Small Molecule Libraries*/chemistry ; Small Molecule Libraries*/Small Molecule Libraries*/Small Molecule Libraries*/pharmacology ; Small Molecule Libraries*/Small Molecule Libraries*/Small Molecule Libraries*/metabolism

  • Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2022 Jan 10; Vol. 61 (2), pp. e202109967. Date of Electronic Publication: 2021 Nov 25.Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773

Record details

Read More Add to Saved list
×
Academic Journal

Repositioning Food and Drug Administration-Approved Drugs for Inhibiting Biliverdin IXβ Reductase B as a Novel Thrombocytopenia Therapeutic Target.

  • Authors : Kim M; Protein Structure Research Team, Korea Basic Science Institute, 162 Yeongudanji-Ro, Ochang-Eup, Cheongju-Si, Chungcheongbuk-Do 28119, South Korea.; Department of NMR Based Structural Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.

Subjects: Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*metabolism ; Oxidoreductases Acting on CH-CH Group Donors/Oxidoreductases Acting on CH-CH Group Donors/Oxidoreductases Acting on CH-CH Group Donors/*antagonists & inhibitors ; Small Molecule Libraries/Small Molecule Libraries/Small Molecule Libraries/*metabolism

  • Source: Journal of medicinal chemistry [J Med Chem] 2022 Feb 10; Vol. 65 (3), pp. 2548-2557. Date of Electronic Publication: 2021 Dec 27.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

Record details

Read More Add to Saved list
×
Academic Journal

Identification and validation of selective deubiquitinase inhibitors.

  • Authors : Varca AC; Department of Cancer Biology and the Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.

Subjects: Deubiquitinating Enzymes/Deubiquitinating Enzymes/Deubiquitinating Enzymes/*antagonists & inhibitors ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology ; Small Molecule Libraries/Small Molecule Libraries/Small Molecule Libraries/*pharmacology

  • Source: Cell chemical biology [Cell Chem Biol] 2021 Dec 16; Vol. 28 (12), pp. 1758-1771.e13. Date of Electronic Publication: 2021 Jun 14.Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list
×
Academic Journal

Synthesis and evaluation of potent novel inhibitors of human sulfide:quinone oxidoreductase.

  • Authors : Baugh SDP; Fox Chase Chemical Diversity Center, Inc., Doylestown, PA 18902, USA.; Jackson MR

Subjects: Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology ; Hydrocarbons, Aromatic/Hydrocarbons, Aromatic/Hydrocarbons, Aromatic/*pharmacology ; Oxidoreductases Acting on Sulfur Group Donors/Oxidoreductases Acting on Sulfur Group Donors/Oxidoreductases Acting on Sulfur Group Donors/*antagonists & inhibitors

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Dec 15; Vol. 54, pp. 128443. Date of Electronic Publication: 2021 Nov 09.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

Record details

Read More Add to Saved list
×
  • 1-10 of  811 results for ""Small Molecule Libraries""