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Recent Studies from Washington State University Add New Data to Antiinfectives (Age-dependent Abundance of Cyp450 Enzymes Involved In Metronidazole Metabolism: Application To Pediatric Pbpk Modeling).

Subjects: METRONIDAZOLE; ENZYMES; STATE universities & colleges

• Source: Pediatrics Week; 2024, p1744-1744, 1p

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Genetic variation in metronidazole metabolism and oxidative stress pathways in clinical Giardia lamblia assemblage A and B isolates.

• Authors : Saghaug, Christina S; Klotz, Christian; Kallio, Juha P

Subjects: GIARDIA lamblia; OXIDATIVE stress; NICOTINAMIDE adenine dinucleotide phosphate

• Source: Infection & Drug Resistance; May2019, Vol. 12, p1221-1235, 15p

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H nuclear magnetic resonance study of metronidazole metabolism by perfused rat liver.

• Authors : Allars, Helen; Coleman, Malcolm; Norton, Raymond

• Source: European Journal of Drug Metabolism & Pharmacokinetics; Jul1985, Vol. 10 Issue 3, p253-260, 8p

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Effect of DSS-Induced Ulcerative Colitis and Butyrate on the Cytochrome P450 2A5: Contribution of the Microbiome.

• Authors : Satka, Stefan; Frybortova, Veronika; Zapletalova, Iveta

Subjects: INFLAMMATORY bowel diseases; BUTYRATES; ULCERATIVE colitis

• Source: International Journal of Molecular Sciences; Oct2022, Vol. 23 Issue 19, p11627, 11p

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Impact of Pomegranate Juice on the Pharmacokinetics of CYP3A4- and CYP2C9-Mediated Drugs Metabolism: A Preclinical and Clinical Review.

• Authors : Mansoor, Kenza; Bardees, Razan; Alkhawaja, Bayan

Subjects: POMEGRANATE juice; DRUG metabolism; PHARMACOKINETICS

• Source: Molecules; Mar2023, Vol. 28 Issue 5, p2117, 11p

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Effects of intestinal flora on pharmacokinetics and pharmacodynamics of drugs.

• Authors : Džidić-Krivić, Amina; Kusturica, Jasna; Sher, Emina Karahmet

Subjects: PHARMACOKINETICS; PHARMACODYNAMICS; GUT microbiome

• Source: Drug Metabolism Reviews; Feb-May2023, Vol. 55 Issue 1/2, p126-139, 14p

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Lack of effect of cimetidine on the pharmacokinetics and metabolism of a single oral dose of metronidazole.

• Authors : Loft, S.; Døssing, M.; Sonne, J.

• Source: European Journal of Clinical Pharmacology; 1988, Vol. 35 Issue 1, p65-68, 4p

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Evaluating metronidazole as a novel, safe CYP2A6 phenotyping probe in healthy adults.

• Authors : Stancil, Stephani L.; Pearce, Robin E.; Tyndale, Rachel F.

Subjects: METRONIDAZOLE; PHENOTYPES; DRUG metabolism

• Source: British Journal of Clinical Pharmacology; May2019, Vol. 85 Issue 5, p960-969, 10p, 3 Charts, 4 Graphs

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Inhibition and induction of metronidazole and antipyrine metabolism.

• Authors : Loft, S.; Sonne, J.; Poulsen, H.

• Source: European Journal of Clinical Pharmacology; 1987, Vol. 32 Issue 1, p35-41, 7p

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