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Academic Journal

Mechanism-based inactivation of cytochromes P450: implications in drug interactions and pharmacotherapy.

  • Authors : Tan BH; Division of Applied Biomedical Sciences and Biotechnology, International Medical University, Kuala Lumpur, Malaysia.; Ahemad N

Subjects: Drug Interactions* ; Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/metabolism ; Cytochrome P-450 Enzyme Inhibitors*/Cytochrome P-450 Enzyme Inhibitors*/Cytochrome P-450 Enzyme Inhibitors*/pharmacology

  • Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2024 Sep; Vol. 54 (9), pp. 575-598. Date of Electronic Publication: 2024 Aug 28.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Projections of Drug-Drug Interactions Caused by Time-Dependent Inhibitors of Cytochrome P450 1A2, 2B6, 2C8, 2C9, 2C19, and 2D6 Using In Vitro Data in Static and Dynamic Models .

  • Authors : Tseng E; Pfizer Global Research and Development, Pfizer Inc, United States .; Lin J

Subjects: Drug Interactions*/Drug Interactions*/Drug Interactions*/physiology ; Microsomes, Liver*/Microsomes, Liver*/Microsomes, Liver*/metabolism ; Cytochrome P-450 Enzyme Inhibitors*/Cytochrome P-450 Enzyme Inhibitors*/Cytochrome P-450 Enzyme Inhibitors*/pharmacology

  • Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2024 Feb 26; Vol. 52 (5). Date of Electronic Publication: 2024 Feb 26.Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: United States NLM ID: 9421550 Publication Model:

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Academic Journal

Cytochrome P450 inhibition to decrease dosage and costs of venetoclax and ibrutinib: A proof-of-concept case study.

  • Authors : De la Garza-Salazar F; Department of Hematology, Hospital Universitario 'Dr. José Eleuterio González', Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.; Colunga-Pedraza PR

Subjects: Cytochrome P-450 Enzyme Inhibitors*/Cytochrome P-450 Enzyme Inhibitors*/Cytochrome P-450 Enzyme Inhibitors*/therapeutic use ; Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/metabolism ; Drug Interactions*

  • Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2023 Feb; Vol. 89 (2), pp. 898-902. Date of Electronic Publication: 2022 Nov 22.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Cytochrome P450 interactions are common and consequential in Massachusetts hospital discharges.

  • Authors : McCoy TH; Center for Experimental Drugs and Diagnostics, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Castro VM

Subjects: Cytochrome P-450 Enzyme Inducers/Cytochrome P-450 Enzyme Inducers/Cytochrome P-450 Enzyme Inducers/*metabolism ; Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/*metabolism ; Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*metabolism

  • Source: The pharmacogenomics journal [Pharmacogenomics J] 2018 Apr; Vol. 18 (2), pp. 347-350. Date of Electronic Publication: 2017 Jul 11.Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101083949 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effect of piperine on the bioavailability and pharmacokinetics of rosmarinic acid in rat plasma using UPLC-MS/MS.

  • Authors : Yang JH; a Department of Pharmacy, Jiangyin Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Chinese Medicine , Jiangyin , China.; Mao KJ

Subjects: Drug Interactions*; Alkaloids/Alkaloids/Alkaloids/*pharmacology ; Benzodioxoles/Benzodioxoles/Benzodioxoles/*pharmacology

  • Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2018 Feb; Vol. 48 (2), pp. 178-185. Date of Electronic Publication: 2017 Jul 03.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effect of piperine on CYP2E1 enzyme activity of chlorzoxazone in healthy volunteers.

  • Authors : Bedada SK; a Drug Metabolism and Pharmacokinetics Division, University College of Pharmaceutical Sciences, Kakatiya University , Warangal , Telangana State , India.; Boga PK

Subjects: Drug Interactions*; Alkaloids/Alkaloids/Alkaloids/*pharmacology ; Benzodioxoles/Benzodioxoles/Benzodioxoles/*pharmacology

  • Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2017 Dec; Vol. 47 (12), pp. 1035-1041. Date of Electronic Publication: 2016 Nov 16.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effect of Fluconazole and Itraconazole on the Pharmacokinetics of Erdafitinib in Healthy Adults: A Randomized, Open-Label, Drug-Drug Interaction Study.

  • Authors : Poggesi I; Global Clinical Pharmacology, Quantitative Sciences, Janssen-Cilag SpA, Via Michelangelo Buonarroti 23, 20093, Cologno Monzese, MI, Italy. .; Li LY

Subjects: Drug Interactions*; Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/*pharmacology ; Fluconazole/Fluconazole/Fluconazole/*pharmacology

  • Source: European journal of drug metabolism and pharmacokinetics [Eur J Drug Metab Pharmacokinet] 2020 Feb; Vol. 45 (1), pp. 101-111.Publisher: Springer France Country of Publication: France NLM ID: 7608491 Publication Model: Print Cited Medium: Internet ISSN: 2107-0180

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Academic Journal

Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids.

  • Authors : Kamble SH; Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, FL, USA; Translational Drug Development Core, Clinical and Translational Science Institute, University of Florida, Gainesville, FL, USA.

Subjects: Drug Interactions*; Alkaloids/Alkaloids/Alkaloids/*pharmacology ; Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/*pharmacology

  • Source: Toxicology letters [Toxicol Lett] 2020 Feb 01; Vol. 319, pp. 148-154. Date of Electronic Publication: 2019 Nov 07.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7709027 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

High-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical Interactions.

  • Authors : Li G; University of Illinois at Chicago/National Institutes of Health Center for Botanical Dietary Supplements Research, Department of Medicinal Chemistry and Pharmacognosy, University of Illinois College of Pharmacy, Chicago, Illinois.; Huang K

Subjects: Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/*analysis ; Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/*metabolism ; Drug Interactions/Drug Interactions/Drug Interactions/*physiology

  • Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2015 Nov; Vol. 43 (11), pp. 1670-8. Date of Electronic Publication: 2015 Aug 18.Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: United States NLM ID: 9421550 Publication Model:

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Academic Journal

Contribution of metabolites to P450 inhibition-based drug-drug interactions: scholarship from the drug metabolism leadership group of the innovation and quality consortium metabolite group.

  • Authors : Yu H; Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut (H.Y.); Takeda Pharmaceuticals International Co., Cambridge, Massachusetts (S.K.B.)

Subjects: Drug Interactions*; Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/Cytochrome P-450 Enzyme Inhibitors/*pharmacokinetics ; Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/Cytochrome P-450 Enzyme System/*metabolism

  • Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2015 Apr; Vol. 43 (4), pp. 620-30. Date of Electronic Publication: 2015 Feb 05.Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: United States NLM ID: 9421550 Publication Model:

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  • 1-10 of  157 results for ""Cytochrome P-450 Enzyme Inhibitors""