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Academic Journal

Design and Biophysical Characterization of Second-Generation cyclic peptide LAG-3 inhibitors for cancer immunotherapy.

  • Authors : Calvo-Barreiro L; Department of Radiology, Molecular Imaging Innovations Institute (MI3), Weill Cornell Medicine, New York, NY 10065, USA.; Zhang L

Subjects: Drug Design* ; Immunotherapy* ; Lymphocyte Activation Gene 3 Protein*

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2024 Nov 15; Vol. 113, pp. 129979. Date of Electronic Publication: 2024 Sep 26.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Design, synthesis, and analysis of macrobicyclic peptides for targeting the Gαi protein.

  • Authors : Pepanian A; Pharmaceutical Biochemistry and Bioanalytics, Pharmaceutical Institute, University of Bonn, Bonn, Germany.; Binbay FA

Subjects: Peptides, Cyclic*/Peptides, Cyclic*/Peptides, Cyclic*/chemistry ; Peptides, Cyclic*/Peptides, Cyclic*/Peptides, Cyclic*/chemical synthesis ; Peptides, Cyclic*/Peptides, Cyclic*/Peptides, Cyclic*/pharmacology

  • Source: Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2024 Jun; Vol. 30 (6), pp. e3565. Date of Electronic Publication: 2024 Jan 17.Publisher: John Wiley & Sons Country of Publication: England NLM ID: 9506309 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Expansive discovery of chemically diverse structured macrocyclic oligoamides.

  • Authors : Salveson PJ; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.

Subjects: Amides*/Amides*/Amides*/chemistry ; Amino Acids*/Amino Acids*/Amino Acids*/chemistry ; Biological Products*/Biological Products*/Biological Products*/chemical synthesis

  • Source: Science (New York, N.Y.) [Science] 2024 Apr 26; Vol. 384 (6694), pp. 420-428. Date of Electronic Publication: 2024 Apr 25.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic

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Academic Journal

Computational Design of Novel Cyclic Peptides Endowed with Autophagy-Inhibiting Activity on Cancer Cell Lines.

  • Authors : Albani M; Department of Pharmaceutical Sciences, Università degli Studi di Milano, Via L. Mangiagalli 25, 20133 Milano, Italy.; Fassi EMA

Subjects: Autophagy*/Autophagy*/Autophagy*/drug effects ; Peptides, Cyclic*/Peptides, Cyclic*/Peptides, Cyclic*/pharmacology ; Peptides, Cyclic*/Peptides, Cyclic*/Peptides, Cyclic*/chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 24; Vol. 25 (9). Date of Electronic Publication: 2024 Apr 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Computational Design of Cyclic Peptide Inhibitors of a Bacterial Membrane Lipoprotein Peptidase.

  • Authors : Craven TW; Department of Biochemistry, University of Washington, Seattle, Washington 98195, United States.; Institute for Protein Design, University of Washington, Seattle, Washington 98195, United States.

Subjects: Peptides, Cyclic*/Peptides, Cyclic*/Peptides, Cyclic*/pharmacology ; Peptides, Cyclic*/Peptides, Cyclic*/Peptides, Cyclic*/chemistry ; Peptides, Cyclic*/Peptides, Cyclic*/Peptides, Cyclic*/chemical synthesis

  • Source: ACS chemical biology [ACS Chem Biol] 2024 May 17; Vol. 19 (5), pp. 1125-1130. Date of Electronic Publication: 2024 May 07.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Design, synthesis and activity evaluation of prodrug form JBP485 and Vitamin E for alleviation of NASH.

  • Authors : Wu B; College of Pharmacy, College of Basic Medical Science, Dalian Medical University, Dalian 116044, PR China.; Zheng X

Subjects: Drug Design*; Non-alcoholic Fatty Liver Disease/Non-alcoholic Fatty Liver Disease/Non-alcoholic Fatty Liver Disease/*drug therapy ; Peptides, Cyclic/Peptides, Cyclic/Peptides, Cyclic/*pharmacology

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2022 Jan 15; Vol. 56, pp. 128464. Date of Electronic Publication: 2021 Nov 19.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Design and application of hybrid cyclic-linear peptide-doxorubicin conjugates as a strategy to overcome doxorubicin resistance and toxicity.

  • Authors : Mozaffari S; Center for Targeted Drug Delivery, Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, Irvine, CA, 92618, USA.; Salehi D

Subjects: Drug Design*; Antibiotics, Antineoplastic/Antibiotics, Antineoplastic/Antibiotics, Antineoplastic/*adverse effects ; Doxorubicin/Doxorubicin/Doxorubicin/*adverse effects

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2021 Dec 15; Vol. 226, pp. 113836. Date of Electronic Publication: 2021 Sep 10.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

A designed cyclic peptide based on Trastuzumab used to construct peptide-drug conjugates for its HER2-targeting ability.

  • Authors : Zhou J; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.; Zou Y

Subjects: Drug Design*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Peptides, Cyclic/Peptides, Cyclic/Peptides, Cyclic/*pharmacology

  • Source: Bioorganic chemistry [Bioorg Chem] 2021 Dec; Vol. 117, pp. 105453. Date of Electronic Publication: 2021 Oct 26.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Simplified Theta-defensin [Ser 3,7,12,16 ] RTD-2 Analog Is Involved in Proteasomal Degradation Pathway in Breast Cancer.

  • Authors : Pianka J; Department of Environmental Technology, Faculty of Chemistry, University of Gdansk, Gdansk, Poland.; Gruba N

Subjects: Drug Design*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*drug therapy

  • Source: Anticancer research [Anticancer Res] 2021 Nov; Vol. 41 (11), pp. 5415-5423.Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 8102988 Publication Model: Print Cited Medium: Internet

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Academic Journal

Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites.

  • Authors : Hosseinzadeh P; University of Washington, Department of Biochemistry, Institute for Protein Design, Seattle, WA, USA.; Knight Campus Center, University of Oregon, Eugene, OR, USA.

Subjects: Drug Design* ; Structure-Activity Relationship*; Histone Deacetylase Inhibitors/Histone Deacetylase Inhibitors/Histone Deacetylase Inhibitors/*pharmacology

  • Source: Nature communications [Nat Commun] 2021 Jun 07; Vol. 12 (1), pp. 3384. Date of Electronic Publication: 2021 Jun 07.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  270 results for ""Peptides, Cyclic""