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Academic Journal

Metal-free internal nucleophile-triggered domino route for synthesis of fused quinoxaline [1,4]-diazepine hybrids and the evaluation of their DNA binding properties.

  • Authors : Majhi B; Organic and Medicinal Chemistry Division, CSIR-Indian Institute of Chemical Biology, 4, Raja S. C. Mullick Road, Kolkata 700032, India.; Bora A

Subjects: Quinoxalines*/Quinoxalines*/Quinoxalines*/chemistry ; Quinoxalines*/Quinoxalines*/Quinoxalines*/pharmacology ; Quinoxalines*/Quinoxalines*/Quinoxalines*/chemical synthesis

  • Source: Bioorganic chemistry [Bioorg Chem] 2024 Oct; Vol. 151, pp. 107694. Date of Electronic Publication: 2024 Aug 05.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Substituent effect of benzyl moiety in nitroquinoxaline small molecules upon DNA binding: Cumulative destacking of DNA nucleobases leading to histone eviction.

  • Authors : Pal R; Organic and Medicinal Chemistry Division, CSIR- Indian Institute of Chemical Biology, 4, Raja S.C. Mullick Road, Jadavpur, Kolkata, 700032, West Bengal, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.

Subjects: DNA/DNA/DNA/*chemistry ; Histones/Histones/Histones/*metabolism ; Quinoxalines/Quinoxalines/Quinoxalines/*chemistry

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2022 Feb 05; Vol. 229, pp. 113995. Date of Electronic Publication: 2021 Nov 13.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Integration of [12]aneN3 and Acenaphtho[1,2-b]quinoxaline as non-viral gene vectors with two-photon property for enhanced DNA/siRNA delivery and bioimaging.

  • Authors : Liu JY; Key Laboratory of Radiopharmaceutics, Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.; Liu XY

Subjects: Gene Transfer Techniques* ; Optical Imaging* ; Photons*

  • Source: Bioorganic chemistry [Bioorg Chem] 2021 Aug; Vol. 113, pp. 104983. Date of Electronic Publication: 2021 May 11.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Design, synthesis, molecular docking and anti-proliferative evaluations of [1,2,4]triazolo[4,3-a]quinoxaline derivatives as DNA intercalators and Topoisomerase II inhibitors.

  • Authors : El-Adl K; Pharmaceutical Medicinal Chemistry and Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Nasr City 11884, Cairo, Egypt; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Heliopolis University for Sustainable Development, Cairo, Egypt. Electronic address: .

Subjects: Molecular Docking Simulation*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; DNA/DNA/DNA/*chemistry

  • Source: Bioorganic chemistry [Bioorg Chem] 2020 Dec; Vol. 105, pp. 104399. Date of Electronic Publication: 2020 Oct 21.Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Synthesis, characterization, DNA binding and cytotoxicity studies of two novel Cu(II)-2-(2'-pyridyl) quinoxaline complexes.

  • Authors : Lioli E; Chemistry Department, Inorganic Chemistry Laboratory, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece.; Psycharis V

Subjects: Coordination Complexes*/Coordination Complexes*/Coordination Complexes*/chemical synthesis ; Coordination Complexes*/Coordination Complexes*/Coordination Complexes*/chemistry ; Coordination Complexes*/Coordination Complexes*/Coordination Complexes*/pharmacology

  • Source: Journal of inorganic biochemistry [J Inorg Biochem] 2020 Jul; Vol. 208, pp. 111077. Date of Electronic Publication: 2020 Mar 23.Publisher: Elsevier Country of Publication: United States NLM ID: 7905788 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

On-DNA Derivatization of Quinoxalin-2-ones by Visible-Light-Triggered Alkylation with Carboxylic Acids.

  • Authors : Zhang Y; State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, Sichuan, P.R. China.; Luo H

Subjects: Carboxylic Acids/Carboxylic Acids/Carboxylic Acids/*chemistry ; DNA/DNA/DNA/*chemistry ; Quinoxalines/Quinoxalines/Quinoxalines/*chemistry

  • Source: Bioconjugate chemistry [Bioconjug Chem] 2021 Aug 18; Vol. 32 (8), pp. 1576-1580. Date of Electronic Publication: 2021 Aug 04.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Design, synthesis, molecular modeling and anti-proliferative evaluation of novel quinoxaline derivatives as potential DNA intercalators and topoisomerase II inhibitors.

  • Authors : Ibrahim MK; Medicinal Chemistry Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, 11884, Egypt.; Taghour MS

Subjects: Drug Design*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; DNA/DNA/DNA/*drug effects

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2018 Jul 15; Vol. 155, pp. 117-134. Date of Electronic Publication: 2018 Jun 04.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Design and Discovery of Novel Quinoxaline Derivatives as Dual DNA Intercalators and Topoisomerase II Inhibitors.

  • Authors : Eissa IH; Pharmaceutical Chemistry department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, 11884, Egypt.; El-Naggar AM

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; DNA/DNA/DNA/*drug effects ; DNA Topoisomerases, Type II/DNA Topoisomerases, Type II/DNA Topoisomerases, Type II/*metabolism

  • Source: Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2018; Vol. 18 (2), pp. 195-209.Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 101265649 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Identification of synthetic inhibitors for the DNA binding of intrinsically disordered circadian clock transcription factors.

  • Authors : Hosoya Y; Academic Assembly, Institute of Agriculture, Shinshu University, 8304 Minami-Minowa, Kami-Ina, Nagano 399-4598, Japan. .; Nojo W

Subjects: Circadian Clocks*; ARNTL Transcription Factors/ARNTL Transcription Factors/ARNTL Transcription Factors/*antagonists & inhibitors ; CLOCK Proteins/CLOCK Proteins/CLOCK Proteins/*antagonists & inhibitors

  • Source: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Sep 24; Vol. 56 (76), pp. 11203-11206.Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 9610838 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Ruthenium(II) complexes of saccharin with dipyridoquinoxaline and dipyridophenazine: Structures, biological interactions and photoinduced DNA damage activity.

  • Authors : Kumar P; Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur 208016, Uttar Pradesh, India.; Dasari S

Subjects: DNA/DNA/DNA/*drug effects ; Organometallic Compounds/Organometallic Compounds/Organometallic Compounds/*pharmacology ; Phenazines/Phenazines/Phenazines/*pharmacology

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2017 Aug 18; Vol. 136, pp. 52-62. Date of Electronic Publication: 2017 May 03.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 of  229 results for ""Quinoxalines""