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Academic Journal

Sugar ring alignment and dynamics underline cytarabine and gemcitabine inhibition on Pol η catalyzed DNA synthesis.

  • Authors : Chang C; Department of Biosciences, Rice University, Houston, Texas, USA.; Zhou G

Subjects: Deoxycytidine*/Deoxycytidine*/Deoxycytidine*/analogs & derivatives ; Deoxycytidine*/Deoxycytidine*/Deoxycytidine*/chemistry ; Deoxycytidine*/Deoxycytidine*/Deoxycytidine*/pharmacology

  • Source: The Journal of biological chemistry [J Biol Chem] 2024 Jun; Vol. 300 (6), pp. 107361. Date of Electronic Publication: 2024 May 10.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Downregulation of deoxycytidine kinase in cytarabine-resistant mantle cell lymphoma cells confers cross-resistance to nucleoside analogs gemcitabine, fludarabine and cladribine, but not to other classes of anti-lymphoma agents.

Subjects: Cladribine/Cladribine/Cladribine/*pharmacology ; Cytarabine/Cytarabine/Cytarabine/*pharmacology ; Deoxycytidine/Deoxycytidine/Deoxycytidine/*analogs & derivatives

  • Source: Molecular cancer [Mol Cancer] 2014 Jun 27; Vol. 13, pp. 159. Date of Electronic Publication: 2014 Jun 27.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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Academic Journal

FF-10502, an Antimetabolite with Novel Activity on Dormant Cells, Is Superior to Gemcitabine for Targeting Pancreatic Cancer Cells.

  • Authors : Mima S; FUJIFILM Corporation, Tokyo, Japan (S.M., C.K., T.H., K.S., T.Y., R.U., M.I., N.K., H.N., H.K., T.M., H.F., Y.S., H.I.) and Strategia Therapeutics, Inc., Houston, Texas (L.J.P.).; Kakinuma C

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Cytarabine/Cytarabine/Cytarabine/*analogs & derivatives ; Deoxycytidine/Deoxycytidine/Deoxycytidine/*analogs & derivatives

  • Source: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2018 Jul; Vol. 366 (1), pp. 125-135. Date of Electronic Publication: 2018 Apr 13.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model:

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Academic Journal

Decreased resistance to gemcitabine (2',2'-difluorodeoxycitidine) of cytosine arabinoside-resistant myeloblastic murine and rat leukemia cell lines: role of altered activity and substrate specificity of deoxycytidine kinase.

  • Authors : Bergman AM; Department of Oncology, University Hospital VU, Amsterdam, The Netherlands.; Pinedo HM

Subjects: Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*pharmacology ; Cytarabine/Cytarabine/Cytarabine/*metabolism ; Deoxycytidine/Deoxycytidine/Deoxycytidine/*analogs & derivatives

  • Source: Biochemical pharmacology [Biochem Pharmacol] 1999 Feb 15; Vol. 57 (4), pp. 397-406.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print Cited Medium: Print ISSN: 0006-2952 (Print)

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Academic Journal

Phosphorylation of deoxycytidine analog monophosphates by UMP-CMP kinase: molecular characterization of the human enzyme.

  • Authors : Van Rompay AR; Division of Clinical Virology, Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden.; Johansson M

Subjects: Cytarabine/Cytarabine/Cytarabine/*metabolism ; Deoxycytidine/Deoxycytidine/Deoxycytidine/*analogs & derivatives ; Nucleoside-Phosphate Kinase/Nucleoside-Phosphate Kinase/Nucleoside-Phosphate Kinase/*metabolism

  • Source: Molecular pharmacology [Mol Pharmacol] 1999 Sep; Vol. 56 (3), pp. 562-9.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model: Print

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Inhibition of protein kinase C activator-mediated induction of p21CIP1 and p27KIP1 by deoxycytidine analogs in human leukemia cells: relationship to apoptosis and differentiation.

  • Authors : Vrana JA; Department of Medicine, Medical College of Virginia, Richmond 23298-0230, USA.; Kramer LB

Subjects: Cell Cycle Proteins* ; Tumor Suppressor Proteins*; Cyclins/Cyclins/Cyclins/*biosynthesis

  • Source: Biochemical pharmacology [Biochem Pharmacol] 1999 Jul 01; Vol. 58 (1), pp. 121-31.Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print Cited Medium: Print ISSN: 0006-2952 (Print)

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Academic Journal

Deoxycytidine protects normal bone marrow progenitors against Ara-C and gemcitabine cytotoxicity without compromising their activity against cisplatin-resistant human ovarian cancer cells.

  • Authors : Bhalla K; Department of Medicine, Medical University of South Carolina, Charleston 29425.; Holladay C

Subjects: Bone Marrow Cells*; Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*adverse effects ; Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/Antimetabolites, Antineoplastic/*therapeutic use

  • Source: Gynecologic oncology [Gynecol Oncol] 1992 Apr; Vol. 45 (1), pp. 32-9.Publisher: Academic Press Country of Publication: United States NLM ID: 0365304 Publication Model: Print Cited Medium: Print ISSN: 0090-8258

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Cytotoxic activity of 2',2'-difluorodeoxycytidine, 5-aza-2'-deoxycytidine and cytosine arabinoside in cells transduced with deoxycytidine kinase gene.

  • Authors : Beauséjour CM; Département de pharmacologie, Université de Montréal, Centre de recherche pédiatrique, Hôpital Ste-Justine, Montréal, Qué., Canada.; Gagnon J

Subjects: Azacitidine/Azacitidine/Azacitidine/*analogs & derivatives ; Azacitidine/Azacitidine/Azacitidine/*pharmacology ; Cytarabine/Cytarabine/Cytarabine/*pharmacology

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2002 May 24; Vol. 293 (5), pp. 1478-84.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print Cited Medium: Print ISSN: 0006-291X (Print)

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Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines.

Subjects: Cytarabine/Cytarabine/Cytarabine/*toxicity ; Deoxycytidine/Deoxycytidine/Deoxycytidine/*analogs & derivatives ; Genetic Markers/Genetic Markers/Genetic Markers/*genetics

  • Source: BMC genomics [BMC Genomics] 2014 Feb 01; Vol. 15, pp. 93. Date of Electronic Publication: 2014 Feb 01.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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Academic Journal

Selection of the best blood compartment to measure cytidine deaminase activity to stratify for optimal gemcitabine or cytarabine treatment.

Subjects: Cytarabine/Cytarabine/Cytarabine/*pharmacology ; Cytidine Deaminase/Cytidine Deaminase/Cytidine Deaminase/*blood ; Cytidine Deaminase/Cytidine Deaminase/Cytidine Deaminase/*metabolism

  • Source: Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2014; Vol. 33 (4-6), pp. 403-12.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 100892832 Publication Model: Print Cited Medium: Internet ISSN:

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  • 1-10 of  668 results for ""Deoxycytidine""