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Idiopathic nephrotic syndrome in Syrian children: clinicopathological spectrum, treatment, and outcomes.

• Authors : Wannous, Hala^1,2

Subjects: *KIDNEY disease diagnosis; *BIOPSY; *IMMUNOSUPPRESSIVE agentsSYRIA

• Source: Pediatric Nephrology. Aug2024, Vol. 39 Issue 8, p2413-2422. 10p.

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Recent Findings in Rhabdomyolysis Described by Researchers from University of Toledo (Rhabdomyolysis and Acute Kidney Injury Potentiated By a Drug-drug Interaction Between Cyclosporine, Leflunomide, and Rosuvastatin In a Kidney Transplant...).

Subjects: KIDNEY transplantation; ACUTE kidney failure; ROSUVASTATIN

• Source: Drug Week; 6/21/2024, p358-358, 1p

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Resveratrol attenuates cyclosporin A-induced upregulation of the thromboxane A2 receptor and hypertension via the AMPK/SIRT1 and MAPK/NF-κB pathways in the rat mesenteric artery.

• Authors : Li, Qian¹ (AUTHOR); Cao, Hanjing¹ (AUTHOR); Xu, Xinya^1,2 (AUTHOR)

Subjects: *RESVERATROL; *MESENTERIC artery; *CYCLOSPORINE

• Source: European Journal of Pharmacology. Jun2024, Vol. 972, pN.PAG-N.PAG. 1p.

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Cyclosporin A inhibits PDGF-BB induced hyaluronan synthesis in orbital fibroblasts.

• Authors : Galgoczi, Erika¹ (AUTHOR) ; Molnar, Zsanett¹ (AUTHOR) ; Katko, Monika¹ (AUTHOR)

Subjects: *CYCLOSPORINE; *HYALURONIC acid; *FIBROBLASTS

• Source: Chemico-Biological Interactions. Jun2024, Vol. 396, pN.PAG-N.PAG. 1p.

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LC-MS/MS and EMIT measure the whole blood concentration of cyclosporine A: The two methods yield concordant results within the dynamic range of the latter, but the former shows broader application scenarios.

• Authors : Zhang, Yuan-Yuan¹ (AUTHOR); Guo, Hong-Li¹ (AUTHOR); Wang, Jie¹ (AUTHOR)

Subjects: *LIQUID chromatography-mass spectrometry; *DRUG monitoring; *POISONS

• Source: Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences. Jun2024, Vol. 1240, pN.PAG-N.PAG. 1p.

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Therapeutic Effects of 30 nm Cyclosporin A-Loaded Nanoparticles Using PLGA-PEG-PLGA Triblock Copolymer for Transdermal Delivery in Mouse Models of Psoriasis.

• Authors : Kagawa, Akira; Sato, Akira; Makino, Kimiko

Subjects: TREATMENT effectiveness; CYCLOSPORINE; NANOPARTICLES

• Source: Applied Sciences (2076-3417); May2024, Vol. 14 Issue 9, p3791, 13p

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Cyclosporine-induced kidney damage was halted by sitagliptin and hesperidin via increasing Nrf2 and suppressing TNF-α, NF-κB, and Bax.

• Authors : Abd-Eldayem AM; Department of Medical Pharmacology, Faculty of Medicine, Assiut University, Assiut, Egypt. .; Department of Pharmacology, Faculty of Medicine, Merit University, Sohâg, Egypt. .

Subjects: Hesperidin*/Hesperidin*/Hesperidin*/pharmacology ; Hesperidin*/Hesperidin*/Hesperidin*/therapeutic use ; Kidney Diseases*/Kidney Diseases*/Kidney Diseases*/chemically induced

• Source: Scientific reports [Sci Rep] 2024 Mar 28; Vol. 14 (1), pp. 7434. Date of Electronic Publication: 2024 Mar 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Inhibitors of Cyclophilin A: Current and Anticipated Pharmaceutical Agents for Inflammatory Diseases and Cancers.

• Authors : Zhao, Xuemei¹ (AUTHOR) ; Zhao, Xin¹ (AUTHOR) ; Di, Weihua¹ (AUTHOR)

Subjects: *CYCLOPHILINS; *CYCLOSPORINE; *PEPTIDES

• Source: Molecules. Mar2024, Vol. 29 Issue 6, p1235. 24p.

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Ciclosporin/cyclophosphamide: Various toxicites.

Subjects: *CYCLOSPORINE; *CYCLOPHOSPHAMIDE; *CONGENITAL disorders

• Source: Reactions Weekly. 1/20/2024, Vol. 1991 Issue 1, p68-68. 1p.

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Modeled microgravity unravels the roles of mechanical forces in renal progenitor cell physiology.

• Authors : Melica ME; Department of Clinical and Experimental Biomedical Sciences 'Mario Serio', University of Florence, Viale Morgagni 50, 50134, Florence, Italy.; Cialdai F

Subjects: Weightlessness* ; Podocytes* ; Kidney Diseases*/Kidney Diseases*/Kidney Diseases*/metabolism

• Source: Stem cell research & therapy [Stem Cell Res Ther] 2024 Jan 17; Vol. 15 (1), pp. 20. Date of Electronic Publication: 2024 Jan 17.Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512

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Validation of an automated sample preparation module directly connected to LC-MS/MS (CLAM-LC-MS/MS system) and comparison with conventional immunoassays for quantitation of tacrolimus and cyclosporin A in a clinical setting.

• Authors : Shimada, Tsutomu; Kawakami, Daisuke; Fujita, Arimi

Subjects: CYCLOSPORINE; TACROLIMUS; IMMUNOASSAY

• Source: Journal of Pharmaceutical Health Care & Sciences; 1/8/2024, Vol. 10 Issue 1, p1-7, 7p

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Multitarget therapy with a corticosteroid, cyclosporine and mycophenolate mofetil for idiopathic membranous nephropathy: a prospective randomized controlled trial.

• Authors : Duan, Yajuan¹ (AUTHOR); Bai, Yu¹ (AUTHOR); Guo, Weikang¹ (AUTHOR)

Subjects: *MYCOPHENOLIC acid; *RANDOMIZED controlled trials; *CYCLOSPORINE

• Source: Nephrology Dialysis Transplantation. Jan2024, Vol. 39 Issue 1, p95-102. 8p.

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Red blood cell distribution width as a prognostic factor in patients with aplastic anemia treated with cyclosporin A plus androgen or cyclosporine A alone: a retrospective study.

• Authors : Zhang, Xiaotian¹ (AUTHOR); Zhang, Yanan¹ (AUTHOR); Liu, Fengan¹ (AUTHOR)

Subjects: *CYCLOSPORINE; *ERYTHROCYTES; *APLASTIC anemia

• Source: Hematology. Dec2023, Vol. 28 Issue 1, p1-8. 8p.

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Agricola

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Cyclosporine A induces Epstein–Barr virus reactivation in tree shrew (Tupaia belangeri chinensis) model.

• Authors : Shi, Nan^1,2 (AUTHOR); Chen, Honglin^1,2 (AUTHOR); Lai, Yongjing^1,2 (AUTHOR)

Subjects: *EPSTEIN-Barr virus; *VIRUS reactivation; *MONONUCLEAR leukocytes

• Source: Microbes & Infection. Nov2023, Vol. 25 Issue 8, pN.PAG-N.PAG. 1p.

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Recent Findings in Membranous Nephropathy Described by a Researcher from Capital Medical University (Multitarget therapy with a corticosteroid, cyclosporine and mycophenolate mofetil for idiopathic membranous nephropathy: a prospective...).

Subjects: CYCLOSPORINE; MYCOPHENOLIC acid; CORTICOSTEROIDS

• Source: Clinical Trials Week; 8/14/2023, p1303-1303, 1p

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A simple and accurate LC‑MS/MS method for monitoring cyclosporin A that is suitable for high throughput analysis.

• Authors : Yuan, Ying-Shi^1,2 (AUTHOR); Liao, Jia-Min^1,2 (AUTHOR); Kang, Chun-Min^1,2 (AUTHOR)

Subjects: *LIQUID chromatography-mass spectrometry; *CYCLOSPORINE; *MATRIX effect

• Source: Experimental & Therapeutic Medicine. Jul2023, Vol. 26 Issue 1, pN.PAG-N.PAG. 1p.

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Role of cyclosporin A in the treatment of kidney disease and nephrotoxicity.

• Authors : Yu J; Institute of Clinical Pharmacology, Anhui Medical University, Hefei, China; Key Laboratory of Anti-Inflammatory and Immune Mdicine, Ministry of Education, Hefei, China

Subjects: Kidney Transplantation* ; Kidney Diseases*/Kidney Diseases*/Kidney Diseases*/chemically induced ; Kidney Diseases*/Kidney Diseases*/Kidney Diseases*/drug therapy

• Source: Toxicology [Toxicology] 2023 Jun 15; Vol. 492, pp. 153544. Date of Electronic Publication: 2023 May 09.Publisher: Elsevier Country of Publication: Ireland NLM ID: 0361055 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3185

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Activation of Kir4.1/Kir5.1 contributes to the cyclosporin A‐induced stimulation of the renal NaCl cotransporter and hyperkalemic hypertension.

• Authors : Gao, Zhong‐Xiuzi^1,2,3,4 (AUTHOR); Zhou, Rui^1,2,3,4 (AUTHOR); Li, Ming‐Yan^1,2,3,4 (AUTHOR)

Subjects: *CYCLOSPORINE; *HYPERTENSION; *BLOOD pressure

• Source: Acta Physiologica. Jun2023, Vol. 238 Issue 2, p1-13. 13p. 1 Color Photograph, 7 Graphs.

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Cyclosporin A acts as an insecticide candidate: providing sustainable biocontrol potential for managing Mythimna separata.

• Authors : Sun, Chengxian¹ (AUTHOR); Li, Xin¹ (AUTHOR); Xiao, Zeyu¹ (AUTHOR)

Subjects: *INSECTICIDES; *BIOPESTICIDES; *CYCLOSPORINE

• Source: Journal of Pest Science. Jun2023, Vol. 96 Issue 3, p1103-1115. 13p.

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An investigation of the primary immunosuppressive therapy's influence on kidney transplant survival at one month after transplantation.

• Authors : Tolstyak, Yaroslav¹; Chopyak, Valentyna¹; Havryliuk, Myroslav²

Subjects: *IMMUNOSUPPRESSIVE agents; *KIDNEY transplantation; *CYCLOSPORINE

• Source: Transplant Immunology. Jun2023, Vol. 78, p1-6. 6p.

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An update on therapeutic options for palmoplantar pustulosis: a narrative review and expert recommendations.

• Authors : Xu, Jia-Ming; Wang, Hai-Meng; Jin, Hong-Zhong

Subjects: CYCLOSPORINE; EVIDENCE gaps; EXCIMER lasers

• Source: Expert Review of Clinical Immunology; May2023, Vol. 19 Issue 5, p499-516, 18p

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Immunosuppressive therapy for progressive idiopathic membranous nephropathy: a cost-effectiveness analysis in China.

• Authors : Xu, Wanyi¹ (AUTHOR); Zhang, Zhiqi² (AUTHOR); Li, Dandan¹ (AUTHOR)

Subjects: *IMMUNOSUPPRESSIVE agents; *COST effectiveness; *KIDNEY diseasesCHINA

• Source: BMC Health Services Research. 4/12/2023, Vol. 23 Issue 1, p1-10. 10p. 1 Diagram, 3 Charts, 3 Graphs.

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Cyclosporin A improves the hyperosmotic response in an experimental dry eye model by inhibiting the HMGB1/TLR4/NF-κB signaling pathway.

• Authors : Shen, Jiachao^1,2 (AUTHOR); Liang, Yan^1,2 (AUTHOR); Bi, Zhaojing² (AUTHOR)

Subjects: *HIGH mobility group proteins; *CYCLOSPORINE; *DRY eye syndromes

• Source: Experimental Eye Research. Apr2023, Vol. 229, pN.PAG-N.PAG. 1p.

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PLDLA/TPU Matrix Enriched with Cyclosporine A as a Therapeutic Platform for Immune-Mediated Keratitis (IMMK) in Horses.

• Authors : Padjasek, Martyna^1,2 (AUTHOR); Cisło-Sankowska, Anna^1,2 (AUTHOR); Lis-Bartos, Anna³ (AUTHOR)

Subjects: *KERATITIS; *CYCLOSPORINE; *HORSES

• Source: International Journal of Molecular Sciences. Mar2023, Vol. 24 Issue 6, p5735. 11p.

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