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Academic Journal

Targeting the PDE3B-cAMP-autophagy axis prevents liver injury in long-term supercooling liver preservation.

  • Authors : Jiao X; Organ Transplantation Center, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510080, China.; Li Y

Subjects: Autophagy*/Autophagy*/Autophagy*/drug effects ; Cyclic Nucleotide Phosphodiesterases, Type 3*/Cyclic Nucleotide Phosphodiesterases, Type 3*/Cyclic Nucleotide Phosphodiesterases, Type 3*/metabolism ; Cyclic AMP*/Cyclic AMP*/Cyclic AMP*/metabolism

  • Source: Science translational medicine [Sci Transl Med] 2024 Nov 27; Vol. 16 (775), pp. eadk0636. Date of Electronic Publication: 2024 Nov 27.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic

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Academic Journal

Live Cell Monitoring of Phosphodiesterase Inhibition by Sulfonylurea Drugs.

  • Authors : Berisha F; Department of General and Interventional Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.; Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Subjects: Sulfonylurea Compounds*/Sulfonylurea Compounds*/Sulfonylurea Compounds*/pharmacology ; Guanine Nucleotide Exchange Factors*/Guanine Nucleotide Exchange Factors*/Guanine Nucleotide Exchange Factors*/metabolism ; Cyclic AMP*/Cyclic AMP*/Cyclic AMP*/metabolism

  • Source: Biomolecules [Biomolecules] 2024 Aug 10; Vol. 14 (8). Date of Electronic Publication: 2024 Aug 10.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Academic Journal

Nitration of protein kinase G-Iα modulates cyclic nucleotide crosstalk via phosphodiesterase 3A: Implications for acute lung injury.

  • Authors : Zemskov EA; Department of Medicine, The University of Arizona Health Sciences, Tucson, Arizona, USA.; Wu X

Subjects: Acute Lung Injury*/Acute Lung Injury*/Acute Lung Injury*/metabolism ; Acute Lung Injury*/Acute Lung Injury*/Acute Lung Injury*/genetics ; Acute Lung Injury*/Acute Lung Injury*/Acute Lung Injury*/pathology

  • Source: The Journal of biological chemistry [J Biol Chem] 2021 Aug; Vol. 297 (2), pp. 100946. Date of Electronic Publication: 2021 Jul 10.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Multiple PDE3A modulators act as molecular glues promoting PDE3A-SLFN12 interaction and induce SLFN12 dephosphorylation and cell death.

  • Authors : Yan B; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, People's Republic of China; National Institute of Biological Sciences, 7 Science Park Road, Zhongguancun Life Science Park, Beijing 102206, People's Republic of China.

Subjects: Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology ; Cyclic AMP*/Cyclic AMP*/Cyclic AMP*/metabolism; Cell Death

  • Source: Cell chemical biology [Cell Chem Biol] 2022 Jun 16; Vol. 29 (6), pp. 958-969.e5. Date of Electronic Publication: 2022 Jan 31.Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Synergic PDE3 and PDE4 control intracellular cAMP and cardiac excitation-contraction coupling in a porcine model.

  • Authors : Mika D; INSERM UMR-S 1180, Faculté de Pharmacie, Univ. Paris-SUD, Université paris-Saclay, F-92296 Châtenay-Malabry, France.; Bobin P

Subjects: Cyclic AMP/Cyclic AMP/Cyclic AMP/*metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*genetics ; Cyclic Nucleotide Phosphodiesterases, Type 4/Cyclic Nucleotide Phosphodiesterases, Type 4/Cyclic Nucleotide Phosphodiesterases, Type 4/*genetics

  • Source: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2019 Aug; Vol. 133, pp. 57-66. Date of Electronic Publication: 2019 May 31.Publisher: Academic Press Country of Publication: England NLM ID: 0262322 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Identification and functional study of genetic polymorphisms in cyclic nucleotide phosphodiesterase 3A (PDE3A).

  • Authors : Kim YR; Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine, Inje University, Busan, South Korea.; Yi M

Subjects: Cilostazol/Cilostazol/Cilostazol/*administration & dosage ; Cyclic AMP/Cyclic AMP/Cyclic AMP/*genetics ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*genetics

  • Source: Annals of human genetics [Ann Hum Genet] 2021 Mar; Vol. 85 (2), pp. 80-91. Date of Electronic Publication: 2020 Nov 28.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0416661 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Thrombospondin-1 promotes hemostasis through modulation of cAMP signaling in blood platelets.

  • Authors : Aburima A; Centre for Atherothrombosis and Metabolic Disease, Hull York Medical School, University of Hull, Hull, United Kingdom.; Berger M

Subjects: Blood Platelets/Blood Platelets/Blood Platelets/*physiology ; Cyclic AMP/Cyclic AMP/Cyclic AMP/*physiology ; Hemorrhagic Disorders/Hemorrhagic Disorders/Hemorrhagic Disorders/*genetics

  • Source: Blood [Blood] 2021 Feb 04; Vol. 137 (5), pp. 678-689.Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020

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Academic Journal

Impact of phosphodiesterases PDE3 and PDE4 on 5-hydroxytryptamine receptor4-mediated increase of cAMP in human atrial fibrillation.

  • Authors : Dolce B; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Hamburg, Germany.

Subjects: Atrial Fibrillation/Atrial Fibrillation/Atrial Fibrillation/*metabolism ; Cyclic AMP/Cyclic AMP/Cyclic AMP/*metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/Cyclic Nucleotide Phosphodiesterases, Type 3/*metabolism

  • Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2021 Feb; Vol. 394 (2), pp. 291-298. Date of Electronic Publication: 2020 Sep 19.Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The dual phosphodiesterase 3/4 inhibitor RPL554 stimulates rare class III and IV CFTR mutants.

  • Authors : Turner MJ; Department of Physiology, McGill University, Montreal, Quebec, Canada.; Cystic Fibrosis Translational Research Centre, McGill University, Montreal, Quebec, Canada.

Subjects: Cyclic AMP/Cyclic AMP/Cyclic AMP/*metabolism ; Cystic Fibrosis Transmembrane Conductance Regulator/Cystic Fibrosis Transmembrane Conductance Regulator/Cystic Fibrosis Transmembrane Conductance Regulator/*genetics ; Isoquinolines/Isoquinolines/Isoquinolines/*pharmacology

  • Source: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2020 May 01; Vol. 318 (5), pp. L908-L920. Date of Electronic Publication: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Selective changes in cytosolic β-adrenergic cAMP signals and L-type Calcium Channel regulation by Phosphodiesterases during cardiac hypertrophy.

  • Authors : Abi-Gerges A; Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.; Castro L

Subjects: Calcium Channels, L-Type/Calcium Channels, L-Type/Calcium Channels, L-Type/*metabolism ; Cardiomegaly/Cardiomegaly/Cardiomegaly/*enzymology ; Cyclic AMP/Cyclic AMP/Cyclic AMP/*metabolism

  • Source: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2021 Jan; Vol. 150, pp. 109-121. Date of Electronic Publication: 2020 Oct 25.Publisher: Academic Press Country of Publication: England NLM ID: 0262322 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  146 results for ""Cyclic Nucleotide Phosphodiesterases, Type 3""