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Academic Journal

Design, synthesis, molecular modeling, in vitro evaluation of novel piperidine-containing hydrazone derivatives as cholinesterase inhibitors.

  • Authors : Tok F; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Marmara University, Istanbul, Türkiye.; Baltaş N

Subjects: Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/pharmacology ; Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/chemical synthesis ; Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/Cholinesterase Inhibitors*/chemistry

  • Source: Drug development research [Drug Dev Res] 2024 Aug; Vol. 85 (5), pp. e22240.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8204468 Publication Model: Print Cited Medium: Internet ISSN: 1098-2299

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Academic Journal

Synthesis, biological evaluation and molecular modeling of benzofuran piperidine derivatives as Aβ antiaggregant.

  • Authors : Chowdhury SR; Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmacy, Shanghai Jiao Tong University (SJTU), Shanghai, China.; Gu J

Subjects: Amyloid beta-Peptides/Amyloid beta-Peptides/Amyloid beta-Peptides/*antagonists & inhibitors ; Benzofurans/Benzofurans/Benzofurans/*pharmacology ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*pharmacology

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2021 Oct 15; Vol. 222, pp. 113541. Date of Electronic Publication: 2021 May 25.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Phenoxyethyl Piperidine/Morpholine Derivatives as PAS and CAS Inhibitors of Cholinesterases: Insights for Future Drug Design.

  • Authors : Pourshojaei Y; Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutics Research Center, Kerman University of Medical Sciences, Kerman, Iran.; Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.

Subjects: Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*metabolism ; Butyrylcholinesterase/Butyrylcholinesterase/Butyrylcholinesterase/*metabolism ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*chemistry

  • Source: Scientific reports [Sci Rep] 2019 Dec 27; Vol. 9 (1), pp. 19855. Date of Electronic Publication: 2019 Dec 27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Exploring fluorine-substituted piperidines as potential therapeutics for diabetes mellitus and Alzheimer's diseases.

  • Authors : Mughal EU; Department of Chemistry, University of Gujrat, Gujrat, 50700, Pakistan. Electronic address: .; Hawsawi MB

Subjects: Piperidines*/Piperidines*/Piperidines*/chemistry ; Piperidines*/Piperidines*/Piperidines*/pharmacology ; Piperidines*/Piperidines*/Piperidines*/chemical synthesis

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Jul 05; Vol. 273, pp. 116523. Date of Electronic Publication: 2024 May 21.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Mass spectrometry for characterization of homologous piperidine alkaloids and their activity as acetylcholinesterase inhibitors.

  • Authors : Freitas TR; Instituto de Química, Universidade Federal de Uberlândia, Núcleo de Pesquisa em Produtos Naturais (NuPPeN), 38400-902, Uberlândia-MG, Brazil.; Danuello A

Subjects: Alkaloids*/Alkaloids*/Alkaloids*/analysis ; Alkaloids*/Alkaloids*/Alkaloids*/chemistry ; Alkaloids*/Alkaloids*/Alkaloids*/metabolism

  • Source: Rapid communications in mass spectrometry : RCM [Rapid Commun Mass Spectrom] 2018 Aug 15; Vol. 32 (15), pp. 1303-1310.Publisher: John Wiley And Sons Ltd Country of Publication: England NLM ID: 8802365 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

2D & 3D-QSAR Study on Novel Piperidine and Piperazine Derivatives as Acetylcholinesterase Enzyme Inhibitors.

  • Authors : Nazari M; Department of Pharmaceutical Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Tabatabai SA

Subjects: Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*chemistry ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*pharmacology ; Piperazine/Piperazine/Piperazine/*chemistry

  • Source: Current computer-aided drug design [Curr Comput Aided Drug Des] 2018; Vol. 14 (4), pp. 391-397.Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101265750 Publication Model: Print Cited Medium: Internet

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Academic Journal

In vitro evaluation and in silico screening of synthetic acetylcholinesterase inhibitors bearing functionalized piperidine pharmacophores.

  • Authors : Brahmachari G; Laboratory of Natural Products and Organic Synthesis, Department of Chemistry, Visva-Bharati (a Central University), Santiniketan 731235, West Bengal, India. Electronic address: .; Choo C

Subjects: Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*pharmacology ; Piperidines/Piperidines/Piperidines/*chemistry; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/chemistry

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2015 Aug 01; Vol. 23 (15), pp. 4567-4575. Date of Electronic Publication: 2015 Jun 09.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Synthesis, biological evaluation and molecular docking study of novel piperidine and piperazine derivatives as multi-targeted agents to treat Alzheimer's disease.

  • Authors : Meena P; Bio-Organic Chemistry Laboratory, Dr. B. R. Ambedkar Centre for Biomedical Research, University of Delhi, Delhi 110007, India.; Nemaysh V

Subjects: Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*drug therapy ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*therapeutic use ; Piperazines/Piperazines/Piperazines/*therapeutic use

  • Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2015 Mar 01; Vol. 23 (5), pp. 1135-48. Date of Electronic Publication: 2015 Jan 13.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

An expedient synthesis and screening for antiacetylcholinesterase activity of piperidine embedded novel pentacyclic cage compounds.

Subjects: Drug Evaluation, Preclinical*; Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*metabolism ; Aza Compounds/Aza Compounds/Aza Compounds/*pharmacology

  • Source: Medicinal chemistry (Shariqah (United Arab Emirates)) [Med Chem] 2014 Mar; Vol. 10 (2), pp. 228-36.Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 101240303 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

A facile chemo-, regio- and stereoselective synthesis and cholinesterase inhibitory activity of spirooxindole-pyrrolizine-piperidine hybrids.

  • Authors : Kia Y; School of Chemical Sciences, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia.; Osman H

Subjects: Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*pharmacology ; Cholinesterases/Cholinesterases/Cholinesterases/*metabolism ; Indoles/Indoles/Indoles/*pharmacology

  • Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2013 May 15; Vol. 23 (10), pp. 2979-83. Date of Electronic Publication: 2013 Mar 23.Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  1,452 results for ""PIPERIDINE""