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Academic Journal

Liver-targeted Angptl4 silencing by antisense oligonucleotide treatment attenuates hyperlipidaemia and atherosclerosis development in APOE*3-Leiden.CETP mice.

  • Authors : Modder M; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.

Subjects: Angiopoietin-Like Protein 4*/Angiopoietin-Like Protein 4*/Angiopoietin-Like Protein 4*/genetics ; Angiopoietin-Like Protein 4*/Angiopoietin-Like Protein 4*/Angiopoietin-Like Protein 4*/metabolism ; Atherosclerosis*/Atherosclerosis*/Atherosclerosis*/genetics

  • Source: Cardiovascular research [Cardiovasc Res] 2024 Dec 31; Vol. 120 (17), pp. 2179-2190.Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245

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Editorial & Opinion

Response to Schmidt et al.: Lower activity of cholesteryl ester transfer protein (CETP) and the risk of dementia: a Mendelian randomization analysis.

  • Authors : Anderson EL; Division of Psychiatry, University College London, 149 Tottenham Court Road, W1T 7NF, London, UK. .

Subjects: Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/genetics ; Mendelian Randomization Analysis* ; Dementia*/Dementia*/Dementia*/genetics

  • Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Dec 19; Vol. 16 (1), pp. 264. Date of Electronic Publication: 2024 Dec 19.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Body mass index-dependent association between cholesteryl ester transfer protein variants and atherometabolic risk factors in gestational diabetes mellitus.

  • Authors : Wang Y; Laboratory of Genetic Disease and Perinatal Medicine and Key Laboratory of Birth Defects and Related Diseases of Women and Children of the Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.; Guan L

Subjects: Diabetes, Gestational*/Diabetes, Gestational*/Diabetes, Gestational*/genetics ; Diabetes, Gestational*/Diabetes, Gestational*/Diabetes, Gestational*/blood ; Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/genetics

  • Source: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the Publisher: Informa Healthcare Country of Publication: England NLM ID: 101136916 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Cholesteryl ester transfer protein inhibition: a pathway to reducing risk of morbidity and promoting longevity.

Subjects: Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/antagonists & inhibitors ; Longevity*; Humans

  • Source: Current opinion in lipidology [Curr Opin Lipidol] 2024 Dec 01; Vol. 35 (6), pp. 303-309. Date of Electronic Publication: 2024 Oct 17.Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 9010000 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Obicetrapib exhibits favorable physiochemical and pharmacokinetic properties compared to previous cholesteryl ester transfer protein inhibitors: An integrated summary of results from non-human primate studies and clinical trials.

  • Authors : Nicholls SJ; Victorian Heart Institute, Monash University, Melbourne, Victoria, Australia.; Nelson AJ

Subjects: Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/antagonists & inhibitors ; Oxazolidinones*/Oxazolidinones*/Oxazolidinones*/pharmacokinetics ; Oxazolidinones*/Oxazolidinones*/Oxazolidinones*/administration & dosage

  • Source: Pharmacology research & perspectives [Pharmacol Res Perspect] 2024 Dec; Vol. 12 (6), pp. e70010.Publisher: John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States

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Academic Journal

Correlation analysis of LXR and its target genes COX2 and CETP with the severity of OSAHS in obese young rats.

  • Authors : Lai M; The First Clinical Medicine College of Lanzhou University, Lanzhou, China.; Ye X

Subjects: Liver X Receptors*/Liver X Receptors*/Liver X Receptors*/genetics ; Liver X Receptors*/Liver X Receptors*/Liver X Receptors*/metabolism ; Cyclooxygenase 2*/Cyclooxygenase 2*/Cyclooxygenase 2*/genetics

  • Source: Sleep & breathing = Schlaf & Atmung [Sleep Breath] 2024 Nov 29; Vol. 29 (1), pp. 30. Date of Electronic Publication: 2024 Nov 29.Publisher: Springer Country of Publication: Germany NLM ID: 9804161 Publication Model: Electronic Cited Medium: Internet ISSN: 1522-1709

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Academic Journal

Associations Between Gene Variants of Lipid-Lowering Drug Targets and Adverse Outcomes After Ischemic Stroke.

  • Authors : Sun L; Department of Epidemiology School of Public Health and Jiangsu Key Laboratory of Preventive and Translational Medicine for Major Chronic Non-communicable Diseases Suzhou Medical College of Soochow University Suzhou China.; Zhang Q

Subjects: Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/genetics ; Hydroxymethylglutaryl CoA Reductases*/Hydroxymethylglutaryl CoA Reductases*/Hydroxymethylglutaryl CoA Reductases*/genetics ; Ischemic Stroke*/Ischemic Stroke*/Ischemic Stroke*/genetics

  • Source: Journal of the American Heart Association [J Am Heart Assoc] 2024 Nov 19; Vol. 13 (22), pp. e036544. Date of Electronic Publication: 2024 Nov 15.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Interaction of CETP rs708272 Polymorphism on Trans Fatty Acid Intake and Glucose Metabolism Markers.

Subjects: Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/genetics ; Blood Glucose*/Blood Glucose*/Blood Glucose*/metabolism ; Obesity*/Obesity*/Obesity*/genetics

  • Source: Nutrients [Nutrients] 2024 Oct 29; Vol. 16 (21). Date of Electronic Publication: 2024 Oct 29.Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Lower activity of cholesteryl ester transfer protein (CETP) and the risk of dementia: a Mendelian randomization analysis.

  • Authors : Schmidt AF; Institute of Cardiovascular Science, Faculty of Population Health, University College London, 69-75 Chenies Mews, London, WC1E 6HX, UK. .; UCL British Heart Foundation Research Accelerator, 69-75 Chenies Mews, London, WC1E 6HX, UK. .

Subjects: Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/genetics ; Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/blood ; Mendelian Randomization Analysis*

  • Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Oct 16; Vol. 16 (1), pp. 228. Date of Electronic Publication: 2024 Oct 16.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Obicetrapib: There is still Life in the CETP Inhibitor!

  • Authors : Ogura M; Department of Clinical Laboratory Technology, Faculty of Medical Science, Juntendo University, Chiba, Japan.

Subjects: Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/Cholesterol Ester Transfer Proteins*/antagonists & inhibitors; Humans ; Anticholesteremic Agents/Anticholesteremic Agents/Anticholesteremic Agents/therapeutic use

  • Source: Journal of atherosclerosis and thrombosis [J Atheroscler Thromb] 2024 Oct 01; Vol. 31 (10), pp. 1367-1369. Date of Electronic Publication: 2024 Jun 15.Publisher: Japan Atherosclerosis Society Country of Publication: Japan NLM ID: 9506298 Publication Model: Print-Electronic Cited Medium: Internet

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