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Academic Journal

PHE1-based IgG-like antibody platform provides a novel strategy for enhanced T-cell immunotherapy.

Authors : Lingbin Wang; Haojie Jiang; Xuying Yin

Subjects: ANTIBODY diversity; BISPECIFIC antibodies; T cells

Source: Frontiers in Immunology; 2024, p1-10, 10p

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Academic Journal

Bi-specific T-cell engagers (BiTEs) in prostate cancer and strategies to enhance development: hope for a BiTE-r future.

Authors : Lampe, Harriet; Tam, Laura; Hansen, Aaron R.

Subjects: PROSTATE cancer; T cells; TUMOR microenvironment

Source: Frontiers in Pharmacology; 2024, p1-13, 13p

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Academic Journal

Characterization of anti-drug antibody responses to the T-cell engaging bispecific antibody cibisatamab to understand the impact on exposure.

Authors : Lotz, Gregor P.; Lutz, Achim; Martin-Facklam, Meret

Subjects: BISPECIFIC antibodies; ANTIBODY formation; T cells

Source: Frontiers in Immunology; 2024, p1-12, 12p

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Academic Journal

Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model.

Authors : Zhen Chang; Dan Gao; Liying Liao

Subjects: BISPECIFIC antibodies; GLYCOPROTEINS; LABORATORY mice

Source: Proceedings of the National Academy of Sciences of the United States of America; 6/11/2024, Vol. 121 Issue 24, p1-12, 23p

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Academic Journal

Impact of Treatment Modality and Route of Administration on Cytokine Release Syndrome in Relapsed or Refractory Multiple Myeloma: A Meta‐Analysis.

Authors : Soltantabar, Pooneh; Sharma, Sheena; Wang, Diane

Subjects: CYTOKINE release syndrome; MULTIPLE myeloma; T cells

Source: Clinical Pharmacology & Therapeutics; Jun2024, Vol. 115 Issue 6, p1258-1268, 11p

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Academic Journal

The bispecific B7H3xCD3 antibody CC-3 induces T cell immunity against bone and soft tissue sarcomas.

Authors : Holzmayer, Samuel J.; Liebel, Kai; Hagelstein, Ilona

Subjects: BISPECIFIC antibodies; SARCOMA; T cells

Source: Frontiers in Immunology; 2024, p1-10, 10p

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Academic Journal

Multiple Myeloma: The Role of Autologous Stem Cell Transplantation in the Era of Immunotherapy.

Authors : Rocchi, Serena; Zannetti, Beatrice Anna; Marconi, Giovanni

Subjects: STEM cell transplantation; MULTIPLE myeloma; BISPECIFIC antibodies

Source: Cells (2073-4409); May2024, Vol. 13 Issue 10, p853, 18p

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Academic Journal

T-cell-engaging bispecific antibodies in cancer.

Authors : van de Donk, Niels W C J (AUTHOR); Zweegman, Sonja (AUTHOR)

Subjects: BISPECIFIC antibodies; IPILIMUMAB; CYTOKINE release syndrome

Source: Lancet. Jul2023, Vol. 402 Issue 10396, p142-158. 17p.

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Academic Journal

A novel dual mechanism-of-action bispecific PD-1-IL-2v armed by a "βγ-only" interleukin-2 variant.

Authors : Yongji Jiang; Chuyuan Chen; Yuan Liu

Subjects: INTERLEUKIN-2; KILLER cells; BISPECIFIC antibodies

Source: Frontiers in Immunology; 2024, p1-12, 12p

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Academic Journal

Advancements in cancer immunotherapies targeting CD20: from pioneering monoclonal antibodies to chimeric antigen receptor-modified T cells.

Authors : Dabkowska, Agnieszka; Domka, Krzysztof; Firczuk, Malgorzata

Subjects: T cells; CD20 antigen; CYTOTOXIC T cells

Source: Frontiers in Immunology; 2024, p1-17, 17p

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