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Academic Journal

METTL3-STAT5B interaction facilitates the co-transcriptional m 6 A modification of mRNA to promote breast tumorigenesis.

  • Authors : Bhattarai PY; Research Institute of Pharmaceutical Sciences, College of Pharmacy, Chosun University, Gwangju, 61452, Republic of Korea.; Kim G

Subjects: STAT5 Transcription Factor*/STAT5 Transcription Factor*/STAT5 Transcription Factor*/metabolism ; STAT5 Transcription Factor*/STAT5 Transcription Factor*/STAT5 Transcription Factor*/genetics ; Methyltransferases*/Methyltransferases*/Methyltransferases*/genetics

  • Source: Cancer letters [Cancer Lett] 2024 Oct 28; Vol. 603, pp. 217215. Date of Electronic Publication: 2024 Aug 31.Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Ruxolitinib-loaded poly-ɛ-caprolactone (PCL) nanoparticles inhibit JAK2/STAT5 signaling in BT474 breast cancer cells by downregulating Bcl-2 and Mcl-1.

  • Authors : Celik EG; Department of Molecular Biology and Genetics, Faculty of Science, Bilecik Seyh Edebali University, Bilecik, Turkey. .; Department of Molecular Biology and Genetics, Institute of Graduate Education, Bilecik Şeyh Edebali University, Bilecik, Turkey. .

Subjects: Nitriles*/Nitriles*/Nitriles*/pharmacology ; Pyrazoles*/Pyrazoles*/Pyrazoles*/pharmacology ; Pyrimidines*/Pyrimidines*/Pyrimidines*/pharmacology

  • Source: Molecular biology reports [Mol Biol Rep] 2024 Jul 22; Vol. 51 (1), pp. 832. Date of Electronic Publication: 2024 Jul 22.Publisher: Reidel Country of Publication: Netherlands NLM ID: 0403234 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-4978

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Academic Journal

STAT5 confers lactogenic properties in breast tumorigenesis and restricts metastatic potential.

  • Authors : Lin M; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, USA.; Department of Breast Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun, Jilin, China.

Subjects: Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/pathology ; STAT5 Transcription Factor*/STAT5 Transcription Factor*/STAT5 Transcription Factor*/metabolism; Animals

  • Source: Oncogene [Oncogene] 2022 Nov; Vol. 41 (48), pp. 5214-5222. Date of Electronic Publication: 2022 Oct 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

PTHrP induces STAT5 activation, secretory differentiation and accelerates mammary tumor development.

  • Authors : Grinman DY; Section of Endocrinology and Metabolism, Department of Internal Medicine, Yale School of Medicine, 300 Cedar Street, TAC S120, Box 208020, New Haven, CT, 06520-8020, USA. .; Boras-Granic K

Subjects: Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/pathology ; Mammary Neoplasms, Animal*/Mammary Neoplasms, Animal*/Mammary Neoplasms, Animal*/genetics ; Mammary Neoplasms, Animal*/Mammary Neoplasms, Animal*/Mammary Neoplasms, Animal*/metabolism

  • Source: Breast cancer research : BCR [Breast Cancer Res] 2022 Apr 19; Vol. 24 (1), pp. 30. Date of Electronic Publication: 2022 Apr 19.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment.

  • Authors : Jesser EA; Microbiology, Immunology and Cancer Biology Graduate Program, University of Minnesota, Minneapolis, MN, USA.; Brady NJ

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; STAT5 Transcription Factor/STAT5 Transcription Factor/STAT5 Transcription Factor/*metabolism ; Tumor Microenvironment/Tumor Microenvironment/Tumor Microenvironment/*immunology

  • Source: Breast cancer research : BCR [Breast Cancer Res] 2021 Nov 07; Vol. 23 (1), pp. 104. Date of Electronic Publication: 2021 Nov 07.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Serine residues 726 and 780 have nonredundant roles regulating STAT5a activity in luminal breast cancer.

  • Authors : Woock AE; Department of Pathology, Virginia Commonwealth University, 1101 E. Marshall St, Sanger 4-006A, Richmond, VA, 23298-06629, USA.; Grible JM

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Carcinogenesis/Carcinogenesis/Carcinogenesis/*metabolism ; Neoplasm Proteins/Neoplasm Proteins/Neoplasm Proteins/*metabolism

  • Source: Scientific reports [Sci Rep] 2021 Jun 29; Vol. 11 (1), pp. 13506. Date of Electronic Publication: 2021 Jun 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Prolactin Drives a Dynamic STAT5A/HDAC6/HMGN2 Cis-Regulatory Landscape Exploitable in ER+ Breast Cancer.

  • Authors : Craig JM; Department of Pathology, Virginia Commonwealth University, Richmond, VA, USA.; Wright Center for Clinical and Translational Research, Virginia Commonwealth University, Richmond, VA, USA.

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*genetics ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; HMGN2 Protein/HMGN2 Protein/HMGN2 Protein/*metabolism

  • Source: Endocrinology [Endocrinology] 2021 May 01; Vol. 162 (5).Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375040 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

A Bioinformatic Pipeline Places STAT5A as a miR-650 Target in Poorly Differentiated Aggressive Breast Cancer.

  • Authors : López-Huerta E; M. Sc. Program in Biochemical Science, National Autonomous University of Mexico, 04510 Mexico City, Mexico.; Research Unit in Virology and Cancer, Children's Hospital of Mexico Federico Gómez, 06720 Mexico City, Mexico.

Subjects: Cell Differentiation* ; Computational Biology*; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2020 Oct 19; Vol. 21 (20). Date of Electronic Publication: 2020 Oct 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Histone H1 and Chromosomal Protein HMGN2 Regulate Prolactin-induced STAT5 Transcription Factor Recruitment and Function in Breast Cancer Cells.

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; HMGN2 Protein/HMGN2 Protein/HMGN2 Protein/*physiology ; Histones/Histones/Histones/*physiology

  • Source: The Journal of biological chemistry [J Biol Chem] 2017 Feb 10; Vol. 292 (6), pp. 2237-2254. Date of Electronic Publication: 2016 Dec 29.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Loss of Nuclear Localized Parathyroid Hormone-Related Protein in Primary Breast Cancer Predicts Poor Clinical Outcome and Correlates with Suppressed Stat5 Signaling.

  • Authors : Tran TH; Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin.; Utama FE

Subjects: Signal Transduction*; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*mortality

  • Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2018 Dec 15; Vol. 24 (24), pp. 6355-6366. Date of Electronic Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium:

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  • 1-10 of  161 results for ""STAT5 Transcription Factor""