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Academic Journal

Breast cancers that disseminate to bone marrow acquire aggressive phenotypes through CX43-related tumor-stroma tunnels.

  • Authors : Sinha S; Department of Cellular and Molecular Medicine, School of Medicine, UCSD, La Jolla, California, USA.; Callow BW

Subjects: Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/pathology ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/metabolism ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/genetics

  • Source: The Journal of clinical investigation [J Clin Invest] 2024 Oct 31; Vol. 134 (24). Date of Electronic Publication: 2024 Oct 31.Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium:

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Academic Journal

Ubiquitin-Related Modifier 1 (URM-1) Modulates Cx43 in Breast Cancer Cell Lines.

  • Authors : El-Hajjar L; Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut P.O. Box 11-0236, Lebanon.; Saliba J

Subjects: Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/metabolism ; Connexin 43*/Connexin 43*/Connexin 43*/genetics ; Connexin 43*/Connexin 43*/Connexin 43*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 03; Vol. 24 (3). Date of Electronic Publication: 2023 Feb 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Cx43 deficiency confers EMT-mediated tamoxifen resistance to breast cancer via c-Src/PI3K/Akt pathway.

  • Authors : Wu DP; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Pharmacy School of Xuzhou Medical University, Xuzhou City, Jiangsu Province, 221004, P.R. China.; Department of Pharmacology, Pharmacy School of Xuzhou Medical University, 221004, Xuzhou City, Jiangsu Province, P.R. China.

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*drug therapy ; Connexin 43/Connexin 43/Connexin 43/*metabolism ; Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/*genetics

  • Source: International journal of biological sciences [Int J Biol Sci] 2021 Jun 11; Vol. 17 (10), pp. 2380-2398. Date of Electronic Publication: 2021 Jun 11 (Print Publication: Publisher: Ivyspring International Country of Publication: Australia NLM ID: 101235568 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Specific N-cadherin-dependent pathways drive human breast cancer dormancy in bone marrow.

  • Authors : Sinha G; Rutgers School of Graduate Studies at New Jersey Medical School, Newark, NJ, USA.; Department of Medicine, Hematology/Oncology, Rutgers New Jersey Medicine School, Newark, NJ, USA.

Subjects: Antigens, CD/Antigens, CD/Antigens, CD/*metabolism ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Cadherins/Cadherins/Cadherins/*metabolism

  • Source: Life science alliance [Life Sci Alliance] 2021 Jun 02; Vol. 4 (7). Date of Electronic Publication: 2021 Jun 02 (Print Publication: 2021).Publisher: Life Science Alliance, LLC Country of Publication: United States NLM ID: 101728869 Publication Model: Electronic-Print Cited Medium: Internet

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Academic Journal

Dysregulation of lncRNA-CCRR contributes to brain metastasis of breast cancer by intercellular coupling via regulating connexin 43 expression.

  • Authors : Li D; Department of Neurosurgery, Fudan University Shanghai Cancer Center, Shanghai, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.

Subjects: Gene Expression Regulation, Neoplastic*; Biomarkers, Tumor/Biomarkers, Tumor/Biomarkers, Tumor/*metabolism ; Brain Neoplasms/Brain Neoplasms/Brain Neoplasms/*secondary

  • Source: Journal of cellular and molecular medicine [J Cell Mol Med] 2021 May; Vol. 25 (10), pp. 4826-4834. Date of Electronic Publication: 2021 Apr 01.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Connexin 32 induces pro-tumorigenic features in MCF10A normal breast cells and MDA-MB-231 metastatic breast cancer cells.

  • Authors : Adak A; Department of Molecular Biology and Genetics, Izmir Institute of Technology, Urla, Izmir, Turkey.; Unal YC

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*genetics ; Cell Proliferation/Cell Proliferation/Cell Proliferation/*genetics ; Connexins/Connexins/Connexins/*genetics

  • Source: Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2020 Dec; Vol. 1867 (12), pp. 118851. Date of Electronic Publication: 2020 Sep 09.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731731 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Collective invasion induced by an autocrine purinergic loop through connexin-43 hemichannels.

  • Authors : Khalil AA; Department of Dermatology and Graduate School of Life Science, University of Wuerzburg, Wuerzburg, Germany.; Department of Cell Biology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*genetics ; Connexin 43/Connexin 43/Connexin 43/*genetics ; Neoplasm Invasiveness/Neoplasm Invasiveness/Neoplasm Invasiveness/*genetics

  • Source: The Journal of cell biology [J Cell Biol] 2020 Oct 05; Vol. 219 (10).Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 0375356 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Pro-Apoptotic Effect of Grape Seed Extract on MCF-7 Involves Transient Increase of Gap Junction Intercellular Communication and Cx43 Up-Regulation: A Mechanism of Chemoprevention.

  • Authors : Leone A; National Research Council (CNR), Institute of Science of Food Production (ISPA), Unit of Lecce, Via Prov.le Lecce-Monteroni, 73100 Lecce, Italy. .; Longo C

Subjects: Anticarcinogenic Agents/Anticarcinogenic Agents/Anticarcinogenic Agents/*pharmacology ; Antioxidants/Antioxidants/Antioxidants/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2019 Jul 02; Vol. 20 (13). Date of Electronic Publication: 2019 Jul 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The ubiquitin-specific protease USP8 deubiquitinates and stabilizes Cx43.

  • Authors : Sun J; Department of Breast Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025.; Hu Q

Subjects: Protein Processing, Post-Translational*; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*pathology ; Connexin 43/Connexin 43/Connexin 43/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2018 May 25; Vol. 293 (21), pp. 8275-8284. Date of Electronic Publication: 2018 Apr 06.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

The Complex Subtype-Dependent Role of Connexin 43 (GJA1) in Breast Cancer.

  • Authors : Busby M; INRS-Institut Armand-Frappier, Laval, QC H7V 1B7, Canada. .; Hallett MT

Subjects: Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism ; Connexin 43/Connexin 43/Connexin 43/*metabolism; Animals

  • Source: International journal of molecular sciences [Int J Mol Sci] 2018 Feb 28; Vol. 19 (3). Date of Electronic Publication: 2018 Feb 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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