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Academic Journal

Two Germline Pathogenic Variants in Cancer Susceptibility Genes and Their Null Implication in Breast Cancer Pathogenesis: The Importance of Tumoral Homologous Recombination Deficiency Testing.

Subjects: *HOMOLOGOUS recombination; *CARCINOGENESIS; *CANCER genes

  • Source: JCO Precision Oncology. 12/1/2024, Vol. 8, p1-4. 4p.

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266P Association of RAD51 and efficacy outcomes in patients with HER2-negative breast cancer (BC) and homologous recombination deficiency (HRD): Post-hoc analysis of the GeparOla trial.

Subjects: *HOMOLOGOUS recombination; *TREATMENT effectiveness; *BREAST cancer

  • Source: Annals of Oncology. 2024 Supplement 2, Vol. 35, pS326-S327. 2p.

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Academic Journal

RPS15 Coordinates with CtIP to Facilitate Homologous Recombination and Confer Therapeutic Resistance in Breast Cancer.

Subjects: HOMOLOGOUS recombination; RNA-binding proteins; DOUBLE-strand DNA breaks

  • Source: Radiation Research; Nov2024, Vol. 202 Issue 5, p775-784, 10p

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Genomic Features of Homologous Recombination Deficiency in Breast Cancer: Impact on Testing and Immunotherapy.

Subjects: HOMOLOGOUS recombination; BREAST; PROGRAMMED death-ligand 1

  • Source: Genes; Feb2024, Vol. 15 Issue 2, p162, 22p

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Somatic mutations in four novel genes contribute to homologous recombination deficiency in breast cancer: a real‐world clinical tumor sequencing study.

Subjects: SOMATIC mutation; HOMOLOGOUS recombination; BREAST cancer

  • Source: Journal of Pathology: Clinical Research; Mar2024, Vol. 10 Issue 2, p1-13, 13p

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Relationship between homologous recombination deficiency and clinical features of breast cancer based on genomic scar score.

Subjects: BREAST cancer; SCARS; CHINESE people

  • Source: Breast; Jun2023, Vol. 69, p392-400, 9p

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LBA64 Outcomes of BRCA and in-house homologous recombination deficiency (HRD) testing in women with ovarian and breast cancer: A multicentre registry study.

Subjects: *HOMOLOGOUS recombination; *BREAST cancer; *BRCA genes

  • Source: Annals of Oncology. 2024 Supplement 2, Vol. 35, pS1253-S1253. 1p.

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LBA14 Intensified alkylating chemotherapy with autologous stem cell rescue (IACT) or conventional chemotherapy followed by olaparib (CCT-O) in stage III, HER2-negative, homologous recombination deficient (HRD) breast cancer (BC): Survival results of the randomized-controlled SUBITO trial

Subjects: *HOMOLOGOUS recombination; *BREAST cancer; *STEM cells

  • Source: Annals of Oncology. 2024 Supplement 2, Vol. 35, pS1208-S1208. 1p.

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Academic Journal

E2F8-CENPL pathway contributes to homologous recombination repair and chemoresistance in breast cancer.

Subjects: *HOMOLOGOUS recombination; *DOUBLE-strand DNA breaks; *DNA repair

  • Source: Cellular Signalling. Jun2024, Vol. 118, pN.PAG-N.PAG. 1p.

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Integrated pan-cancer analysis and experimental verification of the roles of meiotic nuclear divisions 1 in breast cancer.

Subjects: *HOMOLOGOUS recombination; *MOLECULAR biology; *BRCA genes

  • Source: Biochemical & Biophysical Research Communications. Dec2024, Vol. 739, pN.PAG-N.PAG. 1p.

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  • 1-10 of  3,563 results for ""HOMOLOGOUS recombination""