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Academic Journal

Mixed cationic liposomes for brain delivery of drugs by the intranasal route: The acetylcholinesterase reactivator 2-PAM as encapsulated drug model.

  • Authors : Pashirova TN; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov St., 8, Kazan, 420088, Russia. Electronic address: .; Zueva IV

Subjects: Drug Delivery Systems*; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/*pharmacology ; Brain/Brain/Brain/*drug effects

  • Source: Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2018 Nov 01; Vol. 171, pp. 358-367. Date of Electronic Publication: 2018 Jul 24.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9315133 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Effect of administration method, animal weight and age on the intranasal delivery of drugs to the brain.

  • Authors : Krishnan JKS; Department of Anatomy, Physiology and Genetics, and Neurosciences Program, Uniformed Services University School of Medicine, USUHS, Bethesda, MD, United States.; Arun P

Subjects: Aging/Aging/Aging/*physiology ; Antidotes/Antidotes/Antidotes/*administration & dosage ; Body Weight/Body Weight/Body Weight/*physiology

  • Source: Journal of neuroscience methods [J Neurosci Methods] 2017 Jul 15; Vol. 286, pp. 16-21. Date of Electronic Publication: 2017 May 10.Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7905558 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Effects of K074 and pralidoxime on antioxidant and acetylcholinesterase response in malathion-poisoned mice.

  • Authors : dos Santos AA; Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, 88040900, Florianópolis, Santa Catarina, Brazil. ; dos Santos DB

Subjects: Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*metabolism ; Antidotes/Antidotes/Antidotes/*pharmacology ; Antioxidants/Antioxidants/Antioxidants/*metabolism

  • Source: Neurotoxicology [Neurotoxicology] 2011 Dec; Vol. 32 (6), pp. 888-95. Date of Electronic Publication: 2011 Jun 22.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 7905589 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Paraoxon has only a minimal effect on pralidoxime brain concentration in rats.

  • Authors : Petroianu GA; Department of Pharmacology and Therapeutics, FMHS, United Arab Emirates University, Al Ain, United Arab Emirates. ; Lorke DE

Subjects: Blood-Brain Barrier/Blood-Brain Barrier/Blood-Brain Barrier/*metabolism ; Brain/Brain/Brain/*metabolism ; Paraoxon/Paraoxon/Paraoxon/*pharmacology

  • Source: Journal of applied toxicology : JAT [J Appl Toxicol] 2007 Jul-Aug; Vol. 27 (4), pp. 350-7.Publisher: John Wiley And Sons Country of Publication: England NLM ID: 8109495 Publication Model: Print Cited Medium: Print ISSN: 0260-437X

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Academic Journal

Blood-brain barrier penetration of novel pyridinealdoxime methiodide (PAM)-type oximes examined by brain microdialysis with LC-MS/MS.

  • Authors : Okuno S; Section of Forensic Medicine, Department of International Health Development, Division of Public Health, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, Japan.; Sakurada K

Subjects: Brain/Brain/Brain/*metabolism ; Chromatography, Liquid/Chromatography, Liquid/Chromatography, Liquid/*methods ; Pralidoxime Compounds/Pralidoxime Compounds/Pralidoxime Compounds/*pharmacokinetics

  • Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2008 Feb 15; Vol. 227 (1), pp. 8-15. Date of Electronic Publication: 2007 Sep 29.Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Pralidoxime--the gold standard of acetylcholinesterase reactivators--reactivation in vitro efficacy.

  • Authors : Kuca K; Centre of Advanced Studies, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic. ; Hrabinova M

Subjects: Acetylcholinesterase/Acetylcholinesterase/Acetylcholinesterase/*metabolism ; Antidotes/Antidotes/Antidotes/*pharmacology ; Brain/Brain/Brain/*metabolism

  • Source: Bratislavske lekarske listy [Bratisl Lek Listy] 2010; Vol. 111 (9), pp. 502-4.Publisher: AEP Press Country of Publication: Slovakia NLM ID: 0065324 Publication Model: Print Cited Medium: Print ISSN: 0006-9248 (Print)

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Academic Journal

Potency of five structurally different acetylcholinesterase reactivators to reactivate human brain cholinesterases inhibited by cyclosarin.

  • Authors : Kuca K; Department of Toxicology, Faculty of Military Health Sciences, University of Defense, Hradec Kralove.,Czech Republic. ; Cabal J

Subjects: Brain/Brain/Brain/*drug effects ; Cholinesterase Reactivators/Cholinesterase Reactivators/Cholinesterase Reactivators/*pharmacology ; Oximes/Oximes/Oximes/*pharmacology

  • Source: Clinical toxicology (Philadelphia, Pa.) [Clin Toxicol (Phila)] 2007 Jun-Aug; Vol. 45 (5), pp. 512-5.Publisher: Informa Healthcare Country of Publication: England NLM ID: 101241654 Publication Model: Print Cited Medium: Print ISSN: 1556-3650

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Academic Journal

Comparison of in vitro potency of oximes (pralidoxime, obidoxime, HI-6) to reactivate sarin-inhibited acetylcholinesterase in various parts of pig brain.

  • Authors : Kuca K; Department of Toxicology, Faculty of Military Health Sciences, PO Box 35/T, 500 01, Hradec Králové, Czech Republic.; Cabal J

Subjects: Brain/Brain/Brain/*enzymology ; Cholinesterase Inhibitors/Cholinesterase Inhibitors/Cholinesterase Inhibitors/*pharmacology ; Cholinesterase Reactivators/Cholinesterase Reactivators/Cholinesterase Reactivators/*pharmacology

  • Source: Journal of applied toxicology : JAT [J Appl Toxicol] 2005 Jul-Aug; Vol. 25 (4), pp. 271-6.Publisher: John Wiley And Sons Country of Publication: England NLM ID: 8109495 Publication Model: Print Cited Medium: Print ISSN: 0260-437X

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Academic Journal

THE PROTECTIVE EFFECT OF PYRIDINE-2-ALDOXIME METHIODIDE (P2AM), BIS-(4-HYDROXYIMINO-METHYL-PYRIDINIUM-1-METHYL)-ETHER DICHLORIDE (TOXOGONIN) AND ATROPINE IN EXPERIMENTAL DDVP POISONING.

Subjects: Antidotes* ; Atropine* ; Blood*

  • Source: Helvetica physiologica et pharmacologica acta [Helv Physiol Pharmacol Acta] 1964; Vol. 22, pp. 174-83.Publisher: Schweizerischer Verein Fur Physiologie, Physiologische Chemie Und Pharmakologie Country of Publication: Switzerland NLM ID: 17330350R Publication Model:

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Academic Journal

SPONTANEOUS AND PRALIDOXIME-INDUCED RE-ACTIVATION OF BRAIN CHOLINESTERASE IN THE CHICKEN AFTER FATAL NITROSTIGMINE (PARATHION) POISONING.

Subjects: Chickens* ; Cholinesterases* ; Enzyme Inhibitors*

  • Source: Acta pharmacologica et toxicologica [Acta Pharmacol Toxicol (Copenh)] 1963; Vol. 20, pp. 174-80.Publisher: Munksgaard International Publishers Country of Publication: Denmark NLM ID: 0370572 Publication Model: Print Cited Medium: Print ISSN:

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  • 1-10 of  54 results for ""Pralidoxime Compounds""