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Toxic and nontoxic components of botulinum neurotoxin complex are evolved from a common ancestral zinc protein

• Authors : Inui, Ken^1,2; Sagane, Yoshimasa¹; Miyata, Keita^1,2

Subjects: *BOTULINUM toxin; *ZINC proteins; *ENDOPEPTIDASES

• Source: Biochemical & Biophysical Research Communications. Mar2012, Vol. 419 Issue 3, p500-504. 5p.

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Crystal structure of Clostridium botulinum neurotoxin protease in a product-bound state: Evidence for noncanonical zinc protease activity.

• Authors : Segelke, Brent; Knapp, Mark; Kadkhodayan, Saloumeh

Subjects: CLOSTRIDIUM botulinum; BOTULINUM toxin; NEURAL transmission

• Source: Proceedings of the National Academy of Sciences of the United States of America; 5/4/2004, Vol. 101 Issue 18, p6888-6893, 6p

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Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A.

• Authors : Yamagata, Atsushi; Ito, Kaori; Suzuki, Takehiro

Subjects: BOTULINUM toxin; ANTICONVULSANTS; POSITRON emission tomography

• Source: Nature Communications; 4/18/2024, Vol. 15 Issue 1, p1-13, 13p

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How Botulinum Neurotoxin Light Chain A1 Maintains Stable Association with the Intracellular Neuronal Plasma Membrane.

• Authors : Gardner, Alexander P.; Barbieri, Joseph T.; Pellett, Sabine

Subjects: BOTULINUM toxin; CELL membranes; BOTULINUM A toxins

• Source: Toxins; Dec2022, Vol. 14 Issue 12, p814, 16p

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Construction and validation of safe Clostridium botulinum Group II surrogate strain producing inactive botulinum neurotoxin type E toxoid.

• Authors : Nowakowska, Maria B.; Selby, Katja; Przykopanski, Adina

Subjects: NEUROTOXIC agents; BOTULINUM toxin; CLOSTRIDIUM botulinum

• Source: Scientific Reports; 2/2/2022, Vol. 12 Issue 1, p1-11, 11p

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Yesterday and Today: The Impact of Research Conducted at Camp Detrick on Botulinum Toxin.

• Authors : Lebeda, Frank J (AUTHOR); Adler, Michael (AUTHOR); Dembek, Zygmunt F (AUTHOR)

Subjects: HISTORY of biological warfare; BOTULINUM toxin; HEALTH facility design & constructionMARYLAND

• Source: Military Medicine. May/Jun2018, Vol. 183 Issue 5/6, p85-95. 11p. 1 Black and White Photograph, 1 Diagram, 1 Graph.

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High resolution crystal structures of the receptor-binding domain of Clostridium botulinum neurotoxin serotypes A and FA.

• Authors : Davies, Jonathan R.; Hackett, Gavin S.; Sai Man Liu

Subjects: BOTULINUM toxin; CRYSTAL structure; NEUROTOXIC agents

• Source: PeerJ; Mar2018, p1-13, 13p

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Toksyna botulinowa w medycynie i kosmetologii - dwustuletnia historia i nowe perspektywy.

• Authors : Zbrojkiewicz, Małgorzata; Lebiedowska, Agata; Błońska-Fajfrowska, Barbara

• Source: Advances in Hygiene & Experimental Medicine / Postepy Higieny i Medycyny Doswiadczalnej; 2018, Vol. 72, p278-289, 12p

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Novel therapeutics based on recombinant botulinum neurotoxins to normalize the release of transmitters and pain mediators.

• Authors : Dolly, J. Oliver; Wang, Jiafu; Zurawski, Tomas H.

Subjects: ANALGESICS; BOTULINUM toxin; EXOCYTOSIS

• Source: FEBS Journal; Dec2011, Vol. 278 Issue 23, p4454-4466, 13p

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Innocuous full-length botulinum neurotoxin targets and promotes the expression of lentiviral vectors in central and autonomic neurons.

• Authors : O'Leary, V B; Ovsepian, S V; Raghunath, A

Subjects: BOTULINUM toxin; GENE targeting; PROMOTERS (Genetics)

• Source: Gene Therapy; Jul2011, Vol. 18 Issue 7, p656-665, 10p, 1 Diagram, 5 Graphs

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