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Academic Journal

Toll-Like Receptor 9 Aggravates Pulmonary Fibrosis by Promoting NLRP3-Mediated Pyroptosis of Alveolar Epithelial Cells.

  • Authors : Ren C; Department of Urology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child development and Disorders, China International Science and Technology Cooperation base of Child Development and Critical Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, People's Republic of China.; Department of Cardiothoracic Surgery, Children's Hospital of Chongqing Medical University , National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation base of Child development and Critical Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, People's Republic of China.

Subjects: Pyroptosis*/Pyroptosis*/Pyroptosis*/physiology ; NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism ; Toll-Like Receptor 9*/Toll-Like Receptor 9*/Toll-Like Receptor 9*/metabolism

  • Source: Inflammation [Inflammation] 2024 Oct; Vol. 47 (5), pp. 1744-1761. Date of Electronic Publication: 2024 Mar 18.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7600105 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Modulating in vitro lung fibroblast activation via senolysis of senescent human alveolar epithelial cells.

  • Authors : Spina JS; AbbVie Bioresearch Center, Worcester, MA 01605, USA.; Department of Biology, Northeastern University, Boston, MA 02115, USA.

Subjects: Fibroblasts*/Fibroblasts*/Fibroblasts*/drug effects ; Fibroblasts*/Fibroblasts*/Fibroblasts*/metabolism ; Bleomycin*/Bleomycin*/Bleomycin*/toxicity

  • Source: Aging [Aging (Albany NY)] 2024 Jun 29; Vol. 16 (13), pp. 10694-10723. Date of Electronic Publication: 2024 Jun 29.Publisher: Impact Journals, LLC Country of Publication: United States NLM ID: 101508617 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Curcumin analogue EF24 prevents alveolar epithelial cell senescence to ameliorate idiopathic pulmonary fibrosis via activation of PTEN.

  • Authors : Zhang Y; Laboratory of Molecular Genetics of Aging and Tumor, Medical School, Kunming University of Science and Technology, Kunming 650500, PR China.; Liu J

Subjects: Idiopathic Pulmonary Fibrosis*/Idiopathic Pulmonary Fibrosis*/Idiopathic Pulmonary Fibrosis*/drug therapy ; Cellular Senescence*/Cellular Senescence*/Cellular Senescence*/drug effects ; PTEN Phosphohydrolase*/PTEN Phosphohydrolase*/PTEN Phosphohydrolase*/metabolism

  • Source: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Oct; Vol. 133, pp. 155882. Date of Electronic Publication: 2024 Jul 27.Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Aging of alveolar type 2 cells induced by Lonp1 deficiency exacerbates pulmonary fibrosis.

  • Authors : Zhu W; Department of Pulmonary and Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.; Tan C

Subjects: Alveolar Epithelial Cells*/Alveolar Epithelial Cells*/Alveolar Epithelial Cells*/metabolism ; Alveolar Epithelial Cells*/Alveolar Epithelial Cells*/Alveolar Epithelial Cells*/pathology ; Bleomycin*/Bleomycin*/Bleomycin*/toxicity

  • Source: Biomolecules & biomedicine [Biomol Biomed] 2024 Sep 06; Vol. 24 (5), pp. 1258-1272. Date of Electronic Publication: 2024 Sep 06.Publisher: Association of Basic Medical Sciences of FBIH Country of Publication: Bosnia and Herzegovina NLM ID: 9918522188506676 Publication Model: Electronic

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Academic Journal

Lipid Deficiency Contributes to Impaired Alveolar Progenitor Cell Function in Aging and Idiopathic Pulmonary Fibrosis.

  • Authors : Liang J; Department of Medicine and Women's Guild Lung Institute, and.; Huang G

Subjects: Idiopathic Pulmonary Fibrosis*/Idiopathic Pulmonary Fibrosis*/Idiopathic Pulmonary Fibrosis*/metabolism ; Idiopathic Pulmonary Fibrosis*/Idiopathic Pulmonary Fibrosis*/Idiopathic Pulmonary Fibrosis*/pathology ; Stem Cells*/Stem Cells*/Stem Cells*/metabolism

  • Source: American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2024 Aug; Vol. 71 (2), pp. 242-253.Publisher: American Thoracic Society Country of Publication: United States NLM ID: 8917225 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Abnormal mitochondrial iron metabolism damages alveolar type II epithelial cells involved in bleomycin-induced pulmonary fibrosis.

  • Authors : Shao M; Department of Physiology, Xiangya School of Medicine, Central South University, Changsha, Hunan 410078, China.; Cheng H

Subjects: Bleomycin* ; Mitochondria*/Mitochondria*/Mitochondria*/metabolism ; Mitochondria*/Mitochondria*/Mitochondria*/drug effects

  • Source: Theranostics [Theranostics] 2024 Apr 15; Vol. 14 (7), pp. 2687-2705. Date of Electronic Publication: 2024 Apr 15 (Print Publication: 2024).Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101552395 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Vasoactive intestinal peptide attenuates bleomycin-induced murine pulmonary fibrosis by inhibiting epithelial-mesenchymal transition: Restoring autophagy in alveolar epithelial cells.

  • Authors : Duan JX; Department of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China; Research Unit of Respiratory Disease, Central South University, Changsha, Hunan 410011, China.

Subjects: Alveolar Epithelial Cells/Alveolar Epithelial Cells/Alveolar Epithelial Cells/*drug effects ; Bleomycin/Bleomycin/Bleomycin/*toxicity ; Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/*drug effects

  • Source: International immunopharmacology [Int Immunopharmacol] 2021 Dec; Vol. 101 (Pt B), pp. 108211. Date of Electronic Publication: 2021 Oct 08.Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Suppressive effect of quercetin against bleomycin-induced epithelial-mesenchymal transition in alveolar epithelial cells.

  • Authors : Takano M; Department of Pharmaceutics and Therapeutics, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan. Electronic address: .; Deguchi J

Subjects: Alveolar Epithelial Cells/Alveolar Epithelial Cells/Alveolar Epithelial Cells/*drug effects ; Bleomycin/Bleomycin/Bleomycin/*toxicity ; Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/*drug effects

  • Source: Drug metabolism and pharmacokinetics [Drug Metab Pharmacokinet] 2020 Dec; Vol. 35 (6), pp. 522-526. Date of Electronic Publication: 2020 Aug 12.Publisher: Elsevier Country of Publication: England NLM ID: 101164773 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-0920

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Academic Journal

Liproxstatin-1 alleviates bleomycin-induced alveolar epithelial cells injury and mice pulmonary fibrosis via attenuating inflammation, reshaping redox equilibrium, and suppressing ROS/p53/α-SMA pathway.

  • Authors : Tao N; Department of Respiratory Medicine and Critical Care, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, China; Graduate School of Peking Union Medical College, Beijing, 100730, China

Subjects: Quinoxalines*/Quinoxalines*/Quinoxalines*/pharmacology ; Quinoxalines*/Quinoxalines*/Quinoxalines*/therapeutic use ; Spiro Compounds*/Spiro Compounds*/Spiro Compounds*/pharmacology

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Apr 30; Vol. 551, pp. 133-139. Date of Electronic Publication: 2021 Mar 15.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Deficiency of CARMA3 attenuates the development of bleomycin induced pulmonary fibrosis.

  • Authors : Wu Y; Department of Thoracic and Cardiovascular Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.; Qi Y

Subjects: Alveolar Epithelial Cells/Alveolar Epithelial Cells/Alveolar Epithelial Cells/*metabolism ; Bleomycin/Bleomycin/Bleomycin/*administration & dosage ; CARD Signaling Adaptor Proteins/CARD Signaling Adaptor Proteins/CARD Signaling Adaptor Proteins/*genetics

  • Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Dec 03; Vol. 581, pp. 81-88. Date of Electronic Publication: 2021 Oct 11.Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  795 results for ""Alveolar Epithelial Cells""