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Academic Journal

Genetic Factors and Delayed TSB Monitoring and Treatment as Risk Factors Associated with Severe Hyperbilirubinemia in Term Neonates Admitted for Phototherapy.

  • Authors : Boo NY; Department of Population Medicine, Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Bandar Sungai Long, Selangor, Malaysia.; Sin S

Subjects: Bilirubin/Bilirubin/Bilirubin/*blood ; Glucosephosphate Dehydrogenase/Glucosephosphate Dehydrogenase/Glucosephosphate Dehydrogenase/*genetics ; Glucuronosyltransferase/Glucuronosyltransferase/Glucuronosyltransferase/*genetics

  • Source: Journal of tropical pediatrics [J Trop Pediatr] 2020 Dec 01; Vol. 66 (6), pp. 569-582.Publisher: Oxford University Press Country of Publication: England NLM ID: 8010948 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Case Study 6: Deconvoluting Hyperbilirubinemia-Differentiating Between Hepatotoxicity and Reversible Inhibition of UGT1A1, MRP2, or OATP1B1 in Drug Development.

Subjects: Bilirubin/Bilirubin/Bilirubin/*analysis ; Glucuronosyltransferase/Glucuronosyltransferase/Glucuronosyltransferase/*metabolism ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*metabolism

  • Source: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2342, pp. 695-707.Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029

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Academic Journal

Influence of Uridine Diphosphate Glucuronosyltransferase Family 1 Member A1 and Solute Carrier Organic Anion Transporter Family 1 Member B1 Polymorphisms and Efavirenz on Bilirubin Disposition in Healthy Volunteers.

  • Authors : Collins KS; Department of Medicine, Division of Clinical Pharmacology (K.S.C., I.F.M., B.T.G., J.L., T.C.S., Z.D.), and Department of Medical and Molecular Genetics (E.B.M., V.M.P.), Indiana University School of Medicine, Indianapolis, Indiana.; Metzger IF

Subjects: Alkynes/Alkynes/Alkynes/*pharmacology ; Benzoxazines/Benzoxazines/Benzoxazines/*pharmacology ; Bilirubin/Bilirubin/Bilirubin/*metabolism

  • Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2020 Mar; Vol. 48 (3), pp. 169-175. Date of Electronic Publication: 2019 Dec 30.Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: United States NLM ID: 9421550 Publication Model:

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Academic Journal

The human organic anion transport protein SLC21A6 is not sufficient for bilirubin transport.

  • Authors : Wang P; Marion Bessin Liver Research Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA.; Kim RB

Subjects: Bilirubin/Bilirubin/Bilirubin/*pharmacokinetics ; Hepatocytes/Hepatocytes/Hepatocytes/*metabolism ; Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/Liver-Specific Organic Anion Transporter 1/*metabolism

  • Source: The Journal of biological chemistry [J Biol Chem] 2003 Jun 06; Vol. 278 (23), pp. 20695-9. Date of Electronic Publication: 2003 Mar 31.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Academic Journal

Another risk factor for neonatal hyperbilirubinemia.

  • Authors : Gourley GR; Division of Pediatric Gastroenterology,Department of Pediatrics, Oregon Health and Science University, CDRCP, Portland, OR, USA.

Subjects: Bilirubin/Bilirubin/Bilirubin/*analysis ; Jaundice, Neonatal/Jaundice, Neonatal/Jaundice, Neonatal/*epidemiology ; Jaundice, Neonatal/Jaundice, Neonatal/Jaundice, Neonatal/*genetics

  • Source: Journal of pediatric gastroenterology and nutrition [J Pediatr Gastroenterol Nutr] 2005 Mar; Vol. 40 (3), pp. 388-9.Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8211545 Publication Model: Print Cited Medium: Print ISSN:

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Academic Journal

Interplay of OATP1A/1B/2B1 uptake transporters and ABCB1 and ABCG2 efflux transporters in the handling of bilirubin and drugs.

  • Authors : Li W; The Netherlands Cancer Institute, Division of Pharmacology, Plesmanlaan 121, Amsterdam 1066 CX, the Netherlands; The Second Affiliated Hospital of Nantong University, Shengli Rd 666, Nantong 226001, China. Electronic address: .

Subjects: ATP Binding Cassette Transporter, Subfamily G, Member 2*/ATP Binding Cassette Transporter, Subfamily G, Member 2*/ATP Binding Cassette Transporter, Subfamily G, Member 2*/metabolism ; ATP Binding Cassette Transporter, Subfamily G, Member 2*/ATP Binding Cassette Transporter, Subfamily G, Member 2*/ATP Binding Cassette Transporter, Subfamily G, Member 2*/genetics ; Bilirubin*/Bilirubin*/Bilirubin*/blood

  • Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Jun; Vol. 175, pp. 116644. Date of Electronic Publication: 2024 Apr 30.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Effect of genetic variants of bilirubin metabolism on the degree of hyperbilirubinemia in African-American newborns.

  • Authors : Schutzman DL; Department of Pediatrics and Adolescent Medicine, Einstein Medical Center, Philadelphia, PA, USA.; Baudhuin LM

Subjects: Black or African American/Black or African American/Black or African American/*genetics ; Bilirubin/Bilirubin/Bilirubin/*blood ; Bilirubin/Bilirubin/Bilirubin/*metabolism

  • Source: Journal of perinatology : official journal of the California Perinatal Association [J Perinatol] 2017 Apr; Vol. 37 (4), pp. 432-435. Date of Electronic Publication: 2016 Dec 15.Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 8501884 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Octreotide inhibits the bilirubin carriers organic anion transporting polypeptides 1B1 and 1B3 and the multidrug resistance-associated protein 2.

  • Authors : Visentin M; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, Switzerland (M.V., B.S., G.A.K.-U.); and Discovery and Investigative Safety, Novartis Institutes for BioMedical Research, Basel, Switzerland (M.M., G.A.K.-U.).

Subjects: ATP Binding Cassette Transporter, Subfamily B/ATP Binding Cassette Transporter, Subfamily B/ATP Binding Cassette Transporter, Subfamily B/*antagonists & inhibitors ; Bilirubin/Bilirubin/Bilirubin/*metabolism ; Octreotide/Octreotide/Octreotide/*adverse effects

  • Source: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2015 Nov; Vol. 355 (2), pp. 145-51. Date of Electronic Publication: 2015 Sep 01.Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model:

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Academic Journal

Multiple Genetic Modifiers of Bilirubin Metabolism Involvement in Significant Neonatal Hyperbilirubinemia in Patients of Chinese Descent.

  • Authors : Yang H; Laboratory Medical Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province, P. R. China; Central Laboratory, Chaozhou Central Hospital Affiliated to Southern Medical University, Chaozhou, Guangdong Province, P. R. China.

Subjects: Genetic Predisposition to Disease*; Asian People/Asian People/Asian People/*genetics ; Bilirubin/Bilirubin/Bilirubin/*metabolism

  • Source: PloS one [PLoS One] 2015 Jul 06; Vol. 10 (7), pp. e0132034. Date of Electronic Publication: 2015 Jul 06 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Genome-wide association study to characterize serum bilirubin elevations in patients with HCV treated with GS-9256, an HCV NS3 serine protease inhibitor.

  • Authors : Nelson D; Department of Medicine, University of Florida, Gainesville, FL, USA.; Yoshida EM

Subjects: Genome-Wide Association Study* ; Pharmacogenetics*; Antiviral Agents/Antiviral Agents/Antiviral Agents/*therapeutic use

  • Source: Antiviral therapy [Antivir Ther] 2014; Vol. 19 (7), pp. 679-86. Date of Electronic Publication: 2014 Feb 06.Publisher: SAGE Publications Country of Publication: England NLM ID: 9815705 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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