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Academic Journal

Trivalent chromium induces autophagy by activating sphingomyelin phosphodiesterase 2 and increasing cellular ceramide levels in renal HK2 cells.

  • Authors : Yang CL; Graduate Institute of Biomedical Sciences, National Chung Hsing University, Taichung, Taiwan.; Chiou SH

Subjects: Autophagy/Autophagy/Autophagy/*drug effects ; Ceramides/Ceramides/Ceramides/*metabolism ; Chromium/Chromium/Chromium/*pharmacology

  • Source: Molecular carcinogenesis [Mol Carcinog] 2017 Nov; Vol. 56 (11), pp. 2424-2433. Date of Electronic Publication: 2017 Sep 15.Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8811105 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Inhibition of acid sphingomyelinase disrupts LYNUS signaling and triggers autophagy.

  • Authors : Justice MJ; Departments of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202; Department of Medicine, National Jewish Health, Denver, CO 80206.

Subjects: Autophagy/Autophagy/Autophagy/*drug effects ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology ; Lysosomes/Lysosomes/Lysosomes/*drug effects

  • Source: Journal of lipid research [J Lipid Res] 2018 Apr; Vol. 59 (4), pp. 596-606. Date of Electronic Publication: 2018 Jan 29.Publisher: Elsevier Country of Publication: United States NLM ID: 0376606 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Contribution of p62/SQSTM1 to PDGF-BB-induced myofibroblast-like phenotypic transition in vascular smooth muscle cells lacking Smpd1 gene.

  • Authors : Zhang P; Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, USA.

Subjects: Atherosclerosis/Atherosclerosis/Atherosclerosis/*genetics ; Autophagy/Autophagy/Autophagy/*genetics ; Sequestosome-1 Protein/Sequestosome-1 Protein/Sequestosome-1 Protein/*genetics

  • Source: Cell death & disease [Cell Death Dis] 2018 Nov 19; Vol. 9 (12), pp. 1145. Date of Electronic Publication: 2018 Nov 19.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Activation of neutral sphingomyelinase 2 by starvation induces cell-protective autophagy via an increase in Golgi-localized ceramide.

  • Authors : Back MJ; Department of Environmental and Health Chemistry, College of Pharmacy, Chung-Ang University, 84 Heukseok-ro, Dongjak-gu, Seoul, 06974, Republic of Korea.; Ha HC

Subjects: Autophagy*; Ceramides/Ceramides/Ceramides/*metabolism ; Golgi Apparatus/Golgi Apparatus/Golgi Apparatus/*metabolism

  • Source: Cell death & disease [Cell Death Dis] 2018 Jun 04; Vol. 9 (6), pp. 670. Date of Electronic Publication: 2018 Jun 04.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis.

  • Authors : Fucho R; Department of Cell Death and Proliferation, IIBB-CSIC, Barcelona, Spain; Liver Unit, IDIBAPS Hospital Clinic de Barcelona and CIBEREHD, Barcelona, Spain.

Subjects: Autophagy/Autophagy/Autophagy/*physiology ; Non-alcoholic Fatty Liver Disease/Non-alcoholic Fatty Liver Disease/Non-alcoholic Fatty Liver Disease/*enzymology ; Non-alcoholic Fatty Liver Disease/Non-alcoholic Fatty Liver Disease/Non-alcoholic Fatty Liver Disease/*prevention & control

  • Source: Journal of hepatology [J Hepatol] 2014 Nov; Vol. 61 (5), pp. 1126-34. Date of Electronic Publication: 2014 Jun 16.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease.

  • Authors : Lee JK; Stem Cell Neuroplasticity Research Group, Department of Physiology, Cell and Matrix Research Institute, School of Medicine, Department of Biomedical Science, BK21 Plus KNU Biomedical Convergence Program, Department of Laboratory Animal Medicine, College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, KoreaStem Cell Neuroplasticity Research Group, Department of Physiology, Cell and Matrix Research Institute, School of Medicine, Department of Biomedical Science, BK21 Plus KNU Biomedical Convergence Program, Department of Laboratory Animal Medicine, College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, KoreaStem Cell Neuroplasticity Research Group, Department of Physiology, Cell and Matrix Research Institute, School of Medicine, Department of Biomedical Science, BK21 Plus KNU Biomedical Convergence Program, Department of Laboratory Animal Medicine, College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea.; Jin HK

Subjects: Autophagy*; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*enzymology ; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*pathology

  • Source: The Journal of experimental medicine [J Exp Med] 2014 Jul 28; Vol. 211 (8), pp. 1551-70. Date of Electronic Publication: 2014 Jul 21.Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Control of autophagy maturation by acid sphingomyelinase in mouse coronary arterial smooth muscle cells: protective role in atherosclerosis.

  • Authors : Li X; Department of Pharmacology and Toxicology, School of Medicine, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA, 23298, USA.; Xu M

Subjects: Autophagy*; Atherosclerosis/Atherosclerosis/Atherosclerosis/*enzymology ; Coronary Vessels/Coronary Vessels/Coronary Vessels/*enzymology

  • Source: Journal of molecular medicine (Berlin, Germany) [J Mol Med (Berl)] 2014 May; Vol. 92 (5), pp. 473-85. Date of Electronic Publication: 2014 Jan 25.Publisher: Springer International Country of Publication: Germany NLM ID: 9504370 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Essential role for acid sphingomyelinase-inhibited autophagy in melanoma response to cisplatin.

  • Authors : Cervia D; Department for Innovation in Biological, Agro-food and Forest Systems (DIBAF), Università degli Studi della Tuscia, Viterbo, Italy.; Department of Biomedical and Clinical Sciences 'Luigi Sacco' (DIBIC), Università degli Studi di Milano, Milano, Italy.

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Autophagy/Autophagy/Autophagy/*drug effects ; Cisplatin/Cisplatin/Cisplatin/*pharmacology

  • Source: Oncotarget [Oncotarget] 2016 May 03; Vol. 7 (18), pp. 24995-5009.Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN:

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Editorial & Opinion

ASM in Alzheimer's disease.

  • Authors : Lee JK; Stem Cell Neuroplasticity Research Group, Cell and Matrix Research Institute, Kyungpook National University, Daegu, Korea.; Jin HK

Subjects: Autophagy*; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*enzymology ; Alzheimer Disease/Alzheimer Disease/Alzheimer Disease/*pathology

  • Source: Oncotarget [Oncotarget] 2015 Nov 24; Vol. 6 (37), pp. 39389-90.Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The emerging role of acid sphingomyelinase in autophagy.

  • Authors : Perrotta C; Unit of Clinical Pharmacology, Department of Biomedical and Clinical Sciences 'Luigi Sacco' (DIBIC), National Research Council-Institute of Neuroscience, University Hospital 'Luigi Sacco', Università di Milano, 20157, Milan, Italy.; Cervia D

Subjects: Autophagy*; Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/Sphingomyelin Phosphodiesterase/*physiology; Animals

  • Source: Apoptosis : an international journal on programmed cell death [Apoptosis] 2015 May; Vol. 20 (5), pp. 635-44.Publisher: Springer Country of Publication: Netherlands NLM ID: 9712129 Publication Model: Print Cited Medium: Internet ISSN: 1573-675X

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  • 1-10 of  81 results for ""Sphingomyelin Phosphodiesterase""