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Academic Journal

LARP1 binds ribosomes and TOP mRNAs in repressed complexes.

  • Authors : Saba JA; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.

Subjects: Ribonucleoproteins*/Ribonucleoproteins*/Ribonucleoproteins*/metabolism ; Ribonucleoproteins*/Ribonucleoproteins*/Ribonucleoproteins*/genetics ; Ribonucleoproteins*/Ribonucleoproteins*/Ribonucleoproteins*/chemistry

  • Source: The EMBO journal [EMBO J] 2024 Dec; Vol. 43 (24), pp. 6555-6572. Date of Electronic Publication: 2024 Nov 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

LARP1, an RNA-binding protein, participates in ovarian cancer cell survival by regulating mitochondrial oxidative phosphorylation in response to the influence of the PI3K/mTOR pathway.

  • Authors : Ma J; Key Laboratory of Pathobiology, Department of Pathophysiology, Ministry of Education, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.; Dong D

Subjects: TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/TOR Serine-Threonine Kinases*/metabolism ; SS-B Antigen* ; Ovarian Neoplasms*/Ovarian Neoplasms*/Ovarian Neoplasms*/metabolism

  • Source: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2024 Dec; Vol. 1870 (8), pp. 167453. Date of Electronic Publication: 2024 Aug 05.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

eIF4A1 enhances LARP1-mediated translational repression during mTORC1 inhibition.

  • Authors : Shichino Y; RNA Systems Biochemistry Laboratory, RIKEN Cluster for Pioneering Research, Wako, Japan. .; Yamaguchi T

Subjects: Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism ; Ribonucleoproteins*/Ribonucleoproteins*/Ribonucleoproteins*/metabolism ; Ribonucleoproteins*/Ribonucleoproteins*/Ribonucleoproteins*/genetics

  • Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2024 Oct; Vol. 31 (10), pp. 1557-1566. Date of Electronic Publication: 2024 May 21.Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Comparative analysis of the LARP1 C-terminal DM15 region through Coelomate evolution.

  • Authors : Nguyen E; Biological Sciences, University of Pittsburgh, Pittsburgh, PA, United States of America.; Sosa JA

Subjects: Ribonucleoproteins*/Ribonucleoproteins*/Ribonucleoproteins*/metabolism ; Ribonucleoproteins*/Ribonucleoproteins*/Ribonucleoproteins*/genetics ; Ribonucleoproteins*/Ribonucleoproteins*/Ribonucleoproteins*/chemistry

  • Source: PloS one [PLoS One] 2024 Aug 27; Vol. 19 (8), pp. e0308574. Date of Electronic Publication: 2024 Aug 27 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

LARP3, LARP7, and MePCE are involved in the early stage of human telomerase RNA biogenesis.

  • Authors : Kao TL; Department of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Huang YC

Subjects: Autoantigens*/Autoantigens*/Autoantigens*/metabolism ; Autoantigens*/Autoantigens*/Autoantigens*/genetics ; Ribonucleoproteins*/Ribonucleoproteins*/Ribonucleoproteins*/metabolism

  • Source: Nature communications [Nat Commun] 2024 Jul 15; Vol. 15 (1), pp. 5955. Date of Electronic Publication: 2024 Jul 15.Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

LARP6 Regulates Keloid Fibroblast Proliferation, Invasion, and Ability to Synthesize Collagen.

  • Authors : Chen L; Department of Burns and Plastic Surgery, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China.; Su Y

Subjects: Autoantigens*/Autoantigens*/Autoantigens*/genetics ; Autoantigens*/Autoantigens*/Autoantigens*/metabolism ; Cicatrix, Hypertrophic*/Cicatrix, Hypertrophic*/Cicatrix, Hypertrophic*/pathology

  • Source: The Journal of investigative dermatology [J Invest Dermatol] 2022 Sep; Vol. 142 (9), pp. 2395-2405.e7. Date of Electronic Publication: 2022 Feb 15.Publisher: Elsevier Country of Publication: United States NLM ID: 0426720 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The RNA-binding protein La/SSB associates with radiation-induced DNA double-strand breaks in lung cancer cell lines.

  • Authors : Staudacher AH; Translational Oncology Laboratory, Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, South Australia, 5000, Australia.; School of Medicine, University of Adelaide, Adelaide, South Australia, 5000, Australia.

Subjects: Autoantigens*/Autoantigens*/Autoantigens*/genetics ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/radiotherapy

  • Source: Cancer reports (Hoboken, N.J.) [Cancer Rep (Hoboken)] 2022 Aug; Vol. 5 (8), pp. e1543. Date of Electronic Publication: 2021 Oct 12.Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101747728 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Global analysis of RNA-binding proteins identifies a positive feedback loop between LARP1 and MYC that promotes tumorigenesis.

  • Authors : Desi N; Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117596, Singapore.

Subjects: Feedback, Physiological*; Autoantigens/Autoantigens/Autoantigens/*metabolism ; Carcinogenesis/Carcinogenesis/Carcinogenesis/*metabolism

  • Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2022 Feb 23; Vol. 79 (3), pp. 147. Date of Electronic Publication: 2022 Feb 23.Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071

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Academic Journal

S-adenosylmethionine inhibits la ribonucleoprotein domain family member 1 in murine liver and human liver cancer cells.

  • Authors : Ramani K; Karsh Division of Gastroenterology and HepatologyDepartment of MedicineCedars-Sinai Medical CenterLos AngelesCaliforniaUSA.; Robinson AE

Subjects: Autoantigens/Autoantigens/Autoantigens/*metabolism ; Oligonucleotides/Oligonucleotides/Oligonucleotides/*genetics ; RNA-Binding Proteins/RNA-Binding Proteins/RNA-Binding Proteins/*antagonists & inhibitors

  • Source: Hepatology (Baltimore, Md.) [Hepatology] 2022 Feb; Vol. 75 (2), pp. 280-296. Date of Electronic Publication: 2021 Dec 18.Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Characterization of Sequence-Specific Binding of LARP6 to the 5' Stem-Loop of Type I Collagen mRNAs and Implications for Rational Design of Antifibrotic Drugs.

  • Authors : Stefanovic L; Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, FL 32306, USA.; Gordon BH

Subjects: Autoantigens/Autoantigens/Autoantigens/*chemistry ; Collagen Type I/Collagen Type I/Collagen Type I/*chemistry ; Fibrosis/Fibrosis/Fibrosis/*metabolism

  • Source: Journal of molecular biology [J Mol Biol] 2022 Jan 30; Vol. 434 (2), pp. 167394. Date of Electronic Publication: 2021 Dec 08.Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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