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Academic Journal

Valnoctamide, which reduces rat brain arachidonic acid turnover, is a potential non-teratogenic valproate substitute to treat bipolar disorder.

  • Authors : Modi HR; Brain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, 9000 Rockville Pike, Bldg. 9, 1S128, Bethesda, MD 20892, USA.; Ma K

Subjects: Amides/Amides/Amides/*pharmacology ; Antimanic Agents/Antimanic Agents/Antimanic Agents/*pharmacology ; Arachidonic Acid/Arachidonic Acid/Arachidonic Acid/*antagonists & inhibitors

  • Source: Psychiatry research [Psychiatry Res] 2017 Aug; Vol. 254, pp. 279-283. Date of Electronic Publication: 2017 Apr 26.Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Ireland NLM ID: 7911385 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Dietary Linoleic Acid Lowering Reduces Lipopolysaccharide-Induced Increase in Brain Arachidonic Acid Metabolism.

  • Authors : Taha AY; Department of Food Science and Technology, College of Agriculture and Environmental Sciences, University of California, One Shields Avenue, Davis, CA, 95616, USA. .; Blanchard HC

Subjects: Arachidonic Acid/Arachidonic Acid/Arachidonic Acid/*metabolism ; Brain/Brain/Brain/*metabolism ; Dietary Fats/Dietary Fats/Dietary Fats/*pharmacology

  • Source: Molecular neurobiology [Mol Neurobiol] 2017 Aug; Vol. 54 (6), pp. 4303-4315. Date of Electronic Publication: 2016 Jun 23.Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Brain Arachidonic Acid Incorporation and Turnover are not Altered in the Flinders Sensitive Line Rat Model of Human Depression.

  • Authors : Blanchard H; Brain Physiology and Metabolism Section, Laboratory of Neuroscience, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.; Chang L

Subjects: Arachidonic Acid/Arachidonic Acid/Arachidonic Acid/*metabolism ; Brain Chemistry/Brain Chemistry/Brain Chemistry/*genetics ; Depression/Depression/Depression/*genetics

  • Source: Neurochemical research [Neurochem Res] 2015 Nov; Vol. 40 (11), pp. 2293-303. Date of Electronic Publication: 2015 Sep 24.Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7613461 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Valnoctamide, a non-teratogenic amide derivative of valproic acid, inhibits arachidonic acid activation in vitro by recombinant acyl-CoA synthetase-4.

  • Authors : Modi HR; Brain Physiology and Metabolism Section, Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.; Basselin M

Subjects: Amides/Amides/Amides/*pharmacology ; Arachidonic Acid/Arachidonic Acid/Arachidonic Acid/*metabolism ; Coenzyme A Ligases/Coenzyme A Ligases/Coenzyme A Ligases/*drug effects

  • Source: Bipolar disorders [Bipolar Disord] 2014 Dec; Vol. 16 (8), pp. 875-80. Date of Electronic Publication: 2014 Jul 08.Publisher: Wiley-Blackwell Munksgaard Country of Publication: Denmark NLM ID: 100883596 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Coordination of gene expression of arachidonic and docosahexaenoic acid cascade enzymes during human brain development and aging.

  • Authors : Ryan VH; Brain Physiology and Metabolism Section, Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America.; Primiani CT

Subjects: Aging/Aging/Aging/*metabolism ; Arachidonic Acid/Arachidonic Acid/Arachidonic Acid/*pharmacology ; Brain/Brain/Brain/*metabolism

  • Source: PloS one [PLoS One] 2014 Jun 25; Vol. 9 (6), pp. e100858. Date of Electronic Publication: 2014 Jun 25 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Lithium and the other mood stabilizers effective in bipolar disorder target the rat brain arachidonic acid cascade.

  • Authors : Rapoport SI; Brain Physiology and Metabolism Section, Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, United States.

Subjects: Arachidonic Acid/Arachidonic Acid/Arachidonic Acid/*metabolism ; Brain/Brain/Brain/*drug effects ; Brain/Brain/Brain/*metabolism

  • Source: ACS chemical neuroscience [ACS Chem Neurosci] 2014 Jun 18; Vol. 5 (6), pp. 459-67. Date of Electronic Publication: 2014 May 15.Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Transient postnatal fluoxetine leads to decreased brain arachidonic acid metabolism and cytochrome P450 4A in adult mice.

  • Authors : Ramadan E; Brain Physiology and Metabolism Section, Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.; Blanchard H

Subjects: Arachidonic Acid/Arachidonic Acid/Arachidonic Acid/*metabolism ; Cytochrome P-450 CYP4A/Cytochrome P-450 CYP4A/Cytochrome P-450 CYP4A/*metabolism ; Fluoxetine/Fluoxetine/Fluoxetine/*adverse effects

  • Source: Prostaglandins, leukotrienes, and essential fatty acids [Prostaglandins Leukot Essent Fatty Acids] 2014 May; Vol. 90 (5), pp. 191-7. Date of Electronic Publication: 2014 Jan 30.Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 8802730 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

RETRACTED: Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in the postmortem frontal cortex from schizophrenia patients.

  • Authors : Rao JS; Brain Physiology and Metabolism Section, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA. Electronic address: .; Kim HW

Subjects: Arachidonic Acid/Arachidonic Acid/Arachidonic Acid/*metabolism ; Cytokines/Cytokines/Cytokines/*metabolism ; Frontal Lobe/Frontal Lobe/Frontal Lobe/*metabolism

  • Source: Schizophrenia research [Schizophr Res] 2013 Jun; Vol. 147 (1), pp. 24-31. Date of Electronic Publication: 2013 Apr 06.Publisher: Elsevier Science Publisher B. V Country of Publication: Netherlands NLM ID: 8804207 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Propylisopropylacetic acid (PIA), a constitutional isomer of valproic acid, uncompetitively inhibits arachidonic acid acylation by rat acyl-CoA synthetase 4: a potential drug for bipolar disorder.

  • Authors : Modi HR; Brain Physiology and Metabolism Section, National Institute on Aging, Laboratory of Neurosciences, National Institutes of Health, Bethesda, MD, USA. ; Basselin M

Subjects: Acylation/Acylation/Acylation/*drug effects ; Arachidonic Acid/Arachidonic Acid/Arachidonic Acid/*metabolism ; Bipolar Disorder/Bipolar Disorder/Bipolar Disorder/*metabolism

  • Source: Biochimica et biophysica acta [Biochim Biophys Acta] 2013 Apr; Vol. 1831 (4), pp. 880-6. Date of Electronic Publication: 2013 Jan 23.Publisher: Elsevier Pub. Co Country of Publication: Netherlands NLM ID: 0217513 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Aging is associated with altered inflammatory, arachidonic acid cascade, and synaptic markers, influenced by epigenetic modifications, in the human frontal cortex.

  • Authors : Keleshian VL; Brain Physiology and Metabolism Section, Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892-0947, USA.; Modi HR

Subjects: Epigenesis, Genetic*; Aging/Aging/Aging/*metabolism ; Arachidonic Acid/Arachidonic Acid/Arachidonic Acid/*metabolism

  • Source: Journal of neurochemistry [J Neurochem] 2013 Apr; Vol. 125 (1), pp. 63-73. Date of Electronic Publication: 2013 Feb 17.Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic

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