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Academic Journal

Comparison of sGC activator and sGC stimulator in 5/6 nephrectomized rats on high-salt-diet.

Subjects: RENAL fibrosis; HIGH-salt diet; DIASTOLIC blood pressure

  • Source: Frontiers in Pharmacology; 2024, p1-9, 9p

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Academic Journal

Nitro-oleic acid ameliorates erectile dysfunction in a streptozotocin-induced rat model of diabetes by inhibiting oxidative stress and apoptosis and activating the NO/cGMP pathway.

  • Authors : Zhao CB; Department of Urology, Shandong Provincial Hospital, Shandong University, Jinan 250012, China.; Department of Andrology, Liaocheng People's Hospital, Shandong University, Liaocheng 252000, China.

Subjects: Oxidative Stress*/Oxidative Stress*/Oxidative Stress*/drug effects ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Erectile Dysfunction*/Erectile Dysfunction*/Erectile Dysfunction*/drug therapy

  • Source: Asian journal of andrology [Asian J Androl] 2024 Jan 01; Vol. 26 (1), pp. 57-66. Date of Electronic Publication: 2023 Aug 08.Publisher: Shanghai Materia Medica Country of Publication: China NLM ID: 100942132 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Review of Excessive Cytosolic DNA and Its Role in AIM2 and cGAS-STING Mediated Psoriasis Development.

Subjects: CYCLIC guanylic acid; CYCLIC adenylic acid; ADENOSINE monophosphate

  • Source: Clinical, Cosmetic & Investigational Dermatology; Oct2024, Vol. 17, p2345-2357, 13p

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Academic Journal

DNA damage-triggered activation of cGAS-STING pathway induces apoptosis in human keratinocyte HaCaT cells.

Subjects: *SKIN aging; *CYCLIC guanylic acid; *INTERFERON regulatory factors

  • Source: Molecular Immunology. Mar2021, Vol. 131, p180-190. 11p.

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Academic Journal

Repurposing of sildenafil as antitumour; induction of cyclic guanosine monophosphate/protein kinase G pathway, caspase-dependent apoptosis and pivotal reduction of Nuclear factor kappa light chain enhancer of activated B cells in lung cancer.

  • Authors : AboYoussef AM; Pharmacology and Toxicology Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.; Khalaf MM

Subjects: Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/drug therapy ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/metabolism; Apoptosis/Apoptosis/Apoptosis/*drug effects

  • Source: The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2021 Jul 07; Vol. 73 (8), pp. 1080-1091.Publisher: Oxford University Press Country of Publication: England NLM ID: 0376363 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Cyclic GMP and protein kinase-G in myocardial ischaemia-reperfusion: opportunities and obstacles for survival signaling.

Subjects: *CYCLIC guanylic acid; *PROTEIN kinases; *REPERFUSION injury

  • Source: British Journal of Pharmacology. Nov2007, Vol. 152 Issue 6, p855-869. 15p. 2 Diagrams.

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Academic Journal

Functional significance of hsp90 complexes with NOS and sGC in endothelial cells.

Subjects: *HEAT shock proteins; *CYCLIC guanylic acid; *PATHOLOGICAL physiology

  • Source: Clinical Hemorheology & Microcirculation. 2007, Vol. 37 Issue 1-2, p19-35. 17p. 1 Color Photograph, 1 Black and White Photograph, 1 Graph.

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Academic Journal

Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration.

Subjects: *CYCLIC guanylic acid; *DRUG delivery systems; *GENETICS of retinal degeneration

  • Source: Proceedings of the National Academy of Sciences of the United States of America. 3/27/2018, Vol. 115 Issue 13, pE2997-E3006. 10p.

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Academic Journal

JAK2 deficiency improves erectile function in diabetic mice through attenuation of oxidative stress, apoptosis, and fibrosis.

Subjects: TRANSFORMING growth factors-beta; OXIDATIVE stress; CYCLIC guanylic acid

  • Source: Andrology. Sep2021, Vol. 9 Issue 5, p1662-1671. 10p.

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Academic Journal

Hydroalcoholic Extract of Levisticum officinale Increases cGMP Signaling Pathway by Down-Regulating PDE5 Expression and Induction of Apoptosis in MCF-7 and MDA-MB-468 Breast Cancer Cell Lines

  • Authors : Lotfian Sargazi M; Cellular and Molecular Research Center Zahedan University of Medical Sciences, Zahedan, Iran.; Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.

Subjects: Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Cyclic GMP/Cyclic GMP/Cyclic GMP/*metabolism

  • Source: Iranian biomedical journal [Iran Biomed J] 2019 Jul; Vol. 23 (4), pp. 280-6. Date of Electronic Publication: 2018 Nov 03.Publisher: Pasteur Institute of Iran Country of Publication: Iran NLM ID: 9814853 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  168 results for ""CYCLIC guanylic acid""