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Academic Journal

Hydrazinated geraniol derivatives as potential broad-spectrum antiprotozoal agents.

  • Authors : Jooste J; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.; Legoabe LJ

Subjects: Trypanosoma cruzi*/Trypanosoma cruzi*/Trypanosoma cruzi*/drug effects ; Leishmania infantum*/Leishmania infantum*/Leishmania infantum*/drug effects ; Antiprotozoal Agents*/Antiprotozoal Agents*/Antiprotozoal Agents*/pharmacology

  • Source: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2024 Oct; Vol. 357 (10), pp. e2400430. Date of Electronic Publication: 2024 Jul 09.Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Phytochemical profiling and characterization of flavonoid derivatives from propolis sample and investigation of cytotoxic and antiprotozoal activities.

  • Authors : Alanazi S; Clinical Laboratory Sciences Department, College of Applied Medical Sciences, King Saud University, 11451, Riyad, Saudi Arabia. .; Alenzi ND

Subjects: Propolis*/Propolis*/Propolis*/chemistry ; Propolis*/Propolis*/Propolis*/pharmacology ; Antiprotozoal Agents*/Antiprotozoal Agents*/Antiprotozoal Agents*/pharmacology

  • Source: Scientific reports [Sci Rep] 2024 Sep 12; Vol. 14 (1), pp. 21295. Date of Electronic Publication: 2024 Sep 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Aminopyridines in the development of drug candidates against protozoan neglected tropical diseases.

  • Authors : Mustière R; Université de Picardie-Jules-Verne, AGIR - Agents infectieux, RéSistance et chimiothérapie, UR 4294, UFR de pharmacie, 1, Rue des Louvels, F-80037 Amiens cedex 1, France.; Dassonville-Klimpt A

Subjects: Neglected Diseases*/Neglected Diseases*/Neglected Diseases*/drug therapy ; Antiprotozoal Agents*/Antiprotozoal Agents*/Antiprotozoal Agents*/pharmacology ; Antiprotozoal Agents*/Antiprotozoal Agents*/Antiprotozoal Agents*/chemistry

  • Source: Future medicinal chemistry [Future Med Chem] 2024 Jul 02; Vol. 16 (13), pp. 1357-1373. Date of Electronic Publication: 2024 Jun 10.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101511162 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Designing Antitrypanosomal and Antileishmanial BODIPY Derivatives: A Computational and In Vitro Assessment.

  • Authors : Gonçalves RCR; Centre of Chemistry, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.; Advanced (Magnetic) Theranostic Nanostructures Lab, International Iberian Nanotechnology Laboratory, Av. Mestre José Veiga s/n, 4715-330 Braga, Portugal.

Subjects: Boron Compounds*/Boron Compounds*/Boron Compounds*/chemistry ; Boron Compounds*/Boron Compounds*/Boron Compounds*/pharmacology ; Boron Compounds*/Boron Compounds*/Boron Compounds*/chemical synthesis

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Apr 30; Vol. 29 (9). Date of Electronic Publication: 2024 Apr 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Design and synthesis of imidazo[1,2-a]pyridine-chalcone conjugates as antikinetoplastid agents.

  • Authors : Agarwal DS; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.; Beteck RM

Subjects: Antiprotozoal Agents*/Antiprotozoal Agents*/Antiprotozoal Agents*/chemistry ; Chalcones*/Chalcones*/Chalcones*/pharmacology ; Chalcones*/Chalcones*/Chalcones*/therapeutic use

  • Source: Chemical biology & drug design [Chem Biol Drug Des] 2024 Jan; Vol. 103 (1), pp. e14400. Date of Electronic Publication: 2023 Nov 22.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Lead Optimization of the 5-Phenylpyrazolopyrimidinone NPD-2975 toward Compounds with Improved Antitrypanosomal Efficacy.

  • Authors : Zheng Y; Amsterdam Institute of Molecular and Life Sciences, Division of Medicinal Chemistry, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, Amsterdam 1081 HZ, The Netherlands.; van den Kerkhof M

Subjects: Trypanocidal Agents*/Trypanocidal Agents*/Trypanocidal Agents*/pharmacology ; Trypanocidal Agents*/Trypanocidal Agents*/Trypanocidal Agents*/therapeutic use ; Trypanosomiasis, African*/Trypanosomiasis, African*/Trypanosomiasis, African*/drug therapy

  • Source: Journal of medicinal chemistry [J Med Chem] 2024 Feb 22; Vol. 67 (4), pp. 2849-2863. Date of Electronic Publication: 2024 Feb 08.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents.

  • Authors : Linciano P; Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy.; Pozzi C

Subjects: Trypanosoma brucei brucei* ; Antiprotozoal Agents*/Antiprotozoal Agents*/Antiprotozoal Agents*/chemistry ; Chagas Disease*/Chagas Disease*/Chagas Disease*/drug therapy

  • Source: European journal of medicinal chemistry [Eur J Med Chem] 2024 Jan 15; Vol. 264, pp. 115946. Date of Electronic Publication: 2023 Nov 11.Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Synthesis and Evaluation of Marine-Inspired Compounds Result in Hybrids with Antitrypanosomal and Antileishmanial Activities.

  • Authors : Carvalho DT; Laboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.; Laboratory of Research in Pharmaceutical Chemistry, Department of Food and Drugs, Faculty of Pharmaceutical Sciences, Federal University of Alfenas, Rua Gabriel Monteiro da Silva 700, Alfenas 37130-001, Brazil.

Subjects: Antiprotozoal Agents*/Antiprotozoal Agents*/Antiprotozoal Agents*/chemistry ; Anti-Infective Agents* ; Trypanosoma brucei brucei*

  • Source: Marine drugs [Mar Drugs] 2023 Oct 24; Vol. 21 (11). Date of Electronic Publication: 2023 Oct 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101213729 Publication Model: Electronic Cited Medium: Internet ISSN: 1660-3397

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Academic Journal

Synthesis and Biophysical and Biological Studies of N -Phenylbenzamide Derivatives Targeting Kinetoplastid Parasites.

  • Authors : Nué-Martinez JJ; Instituto de Química Médica, IQM-CSIC, Juan de la Cierva 3, E-28006 Madrid, Spain.; PhD Programme in Medicinal Chemistry, Doctoral School, Universidad Complutense de Madrid (UCM), 28040 Madrid, Spain.

Subjects: Antiprotozoal Agents*/Antiprotozoal Agents*/Antiprotozoal Agents*/chemistry ; Leishmania donovani*/Leishmania donovani*/Leishmania donovani*/metabolism ; Parasites*/Parasites*/Parasites*/drug effects

  • Source: Journal of medicinal chemistry [J Med Chem] 2023 Oct 12; Vol. 66 (19), pp. 13452-13480. Date of Electronic Publication: 2023 Sep 20.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

2-Aroyl quinazolinone: Synthesis and in vitro anti-parasitic activity.

  • Authors : Setshedi KJ; Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.; Beteck RM

Subjects: Parasites* ; Antiprotozoal Agents*/Antiprotozoal Agents*/Antiprotozoal Agents*/pharmacology ; Trypanosoma brucei brucei*

  • Source: Chemical biology & drug design [Chem Biol Drug Des] 2023 Oct; Vol. 102 (4), pp. 763-772. Date of Electronic Publication: 2023 Jun 23.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 of  430 results for ""Trypanosoma brucei brucei""