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Biliverdin improved angiogenesis and suppressed apoptosis via PI3K/Akt-mediated Nrf2 antioxidant system to promote ischemic flap survival.

• Authors : Yao Z; Department of Burn, Wound Repair and Regenerative Medicine Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China; Zhejiang Provincial Key Laboratory of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, 325027, China.

Subjects: NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/metabolism ; NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/NF-E2-Related Factor 2*/genetics ; Human Umbilical Vein Endothelial Cells*/Human Umbilical Vein Endothelial Cells*/Human Umbilical Vein Endothelial Cells*/drug effects

• Source: Free radical biology & medicine [Free Radic Biol Med] 2024 Nov 20; Vol. 225, pp. 35-52. Date of Electronic Publication: 2024 Sep 25.Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Physiologically Relevant Levels of Biliverdin Do Not Significantly Oppose Oxidative Damage in Plasma In Vitro.

• Authors : Butler MW; Cullen ZE; Garti CM

Subjects: Biliverdine*/Biliverdine*/Biliverdine*/metabolism ; Antioxidants*/Antioxidants*/Antioxidants*/metabolism; Animals

• Source: Physiological and biochemical zoology : PBZ [Physiol Biochem Zool] 2023 Jul-Aug; Vol. 96 (4), pp. 294-303. Date of Electronic Publication: 2023 Jun 12.Publisher: University of Chicago Press Country of Publication: United States NLM ID: 100883369 Publication Model: Print-Electronic Cited Medium:

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Biliverdin Protects the Isolated Rat Lungs from Ischemia-reperfusion Injury via Antioxidative, Anti-inflammatory and Anti-apoptotic Effects.

• Authors : Tian WF; Department of Pathophysiology, Wuxi Medical School, Jiangnan University, Wuxi, Jiangsu 214122, China.; Weng P

Subjects: Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*therapeutic use ; Antioxidants/Antioxidants/Antioxidants/*therapeutic use ; Biliverdine/Biliverdine/Biliverdine/*therapeutic use

• Source: Chinese medical journal [Chin Med J (Engl)] 2017 Apr 05; Vol. 130 (7), pp. 859-865.Publisher: Chinese Medical Association ; produced by Wolters Kluwer Country of Publication: China NLM ID: 7513795 Publication Model: Print Cited Medium:

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Biliverdin protects against cisplatin-induced apoptosis of renal tubular epithelial cells.

• Authors : Lv Q; Department of Hospital Infection Control, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.; Yao Y

Subjects: Apoptosis*; Antioxidants/Antioxidants/Antioxidants/*pharmacology ; Biliverdine/Biliverdine/Biliverdine/*pharmacology

• Source: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban [J Publisher: Huazhong University of Science and Technology Country of Publication: China NLM ID: 101169627 Publication Model: Print-Electronic Cited Medium:

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Singlet oxygen oxidation products of biliverdin IXα dimethyl ester.

• Authors : Dorazio SJ; Department of Chemistry, University of Connecticut, Storrs, CT 06269-3060, USA.; Halepas S

Subjects: Antioxidants/Antioxidants/Antioxidants/*metabolism ; Biliverdine/Biliverdine/Biliverdine/*analogs & derivatives ; Singlet Oxygen/Singlet Oxygen/Singlet Oxygen/*metabolism

• Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2015 Dec 15; Vol. 23 (24), pp. 7671-5. Date of Electronic Publication: 2015 Nov 14.Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Conversion of biliverdin to bilirubin by biliverdin reductase contributes to endothelial cell protection by heme oxygenase-1-evidence for direct and indirect antioxidant actions of bilirubin.

• Authors : Jansen T; Klinikum der Johannes Gutenberg-Universität Mainz, II. Medizinische Klinik, Kardiologie, 55101 Mainz, Germany.; Hortmann M

Subjects: Cytoprotection*/Cytoprotection*/Cytoprotection*/drug effects; Antioxidants/Antioxidants/Antioxidants/*metabolism ; Bilirubin/Bilirubin/Bilirubin/*metabolism

• Source: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2010 Aug; Vol. 49 (2), pp. 186-95. Date of Electronic Publication: 2010 Apr 27.Publisher: Academic Press Country of Publication: England NLM ID: 0262322 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Limited role for the bilirubin-biliverdin redox amplification cycle in the cellular antioxidant protection by biliverdin reductase.

• Authors : Maghzal GJ; Centre for Vascular Research, School of Medical Sciences (Pathology) and Bosch Institute, Sydney Medical School, University of Sydney, Medical Foundation Building K25, 92-94 Parramatta Road, Camperdown, New South Wales 2006, Australia.; Leck MC

Subjects: Antioxidants/Antioxidants/Antioxidants/*metabolism ; Bilirubin/Bilirubin/Bilirubin/*metabolism ; Biliverdine/Biliverdine/Biliverdine/*metabolism

• Source: The Journal of biological chemistry [J Biol Chem] 2009 Oct 23; Vol. 284 (43), pp. 29251-9. Date of Electronic Publication: 2009 Aug 18.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Cycling the wagons for biliverdin reductase.

• Authors : Sedlak TW; Snyder SH

Subjects: Antioxidants/Antioxidants/Antioxidants/*metabolism ; Biliverdine/Biliverdine/Biliverdine/*metabolism ; Cardiovascular Diseases/Cardiovascular Diseases/Cardiovascular Diseases/*metabolism

• Source: The Journal of biological chemistry [J Biol Chem] 2009 Nov 13; Vol. 284 (46), pp. le11; author reply le12.Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication

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Protection against lung graft injury from brain-dead donors with carbon monoxide, biliverdin, or both.

• Authors : Zhou H; Department of Anesthesiology, The Second Affiliated Hospital, Harbin Medical University, and Hei Long Jiang Province Key Lab of Research on Anesthesiology and Critical Care Medicine, Harbin, China.; Qian H

Subjects: Brain Death*; Antioxidants/Antioxidants/Antioxidants/*administration & dosage ; Biliverdine/Biliverdine/Biliverdine/*administration & dosage

• Source: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation [J Heart Lung Transplant] 2011 Apr; Vol. 30 (4), pp. 460-6.Publisher: Elsevier Country of Publication: United States NLM ID: 9102703 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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